In situ crosslinked biodegradable hydrogels loaded with IL-2 are effective tools for local IL-2 therapy

European Journal of Pharmaceutical Sciences - Tập 21 - Trang 561-567 - 2004
Gert W Bos1, John J.L Jacobs2, Jan Willem Koten2, Sophie Van Tomme1, Theo Veldhuis1, Cornelus F van Nostrum1, Willem Den Otter2,3, Wim E Hennink1
1Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, P.O. Box 80082, 3508 TB Utrecht, The Netherlands
2Faculty of Veterinary Science, Department of Cell Biology and Histology, Utrecht University, P.O. Box 80176, 3508 TD Utrecht, The Netherlands
3Faculty of Veterinary Science, Department of Pathology, Utrecht University, P.O. Box 80158, 3508 TD Utrecht, The Netherlands

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