Life-Threatening Toxicity of Cancer Therapy

Abelson, 1978, Methotrexate and central nervous system toxicity, Cancer Treat Rep, 62, 1999 Arga, 1984, Dexamethasone mediated inhibition of human T cell growth factor and gamma interferon messenger RNA, Immunology, 133, 273 Bersen, 1985, Neurologic amyotrophy and polyradiculopathy during interferon therapy, Lancet, 1, 50, 10.1016/S0140-6736(85)90999-7 Borden EC: Interferons and cancer: How the promise is kept. In Gresser I (ed): Interferon. Vol 5. Orlando, Academic, pp 1983, 43-83 Chapman, 1986, Phase I study of recombinant tumor necrosis factor (rTNF), Proc Am Soc Clin Oncol, 5, 231 Cox, 1979, Cyclophosphamide cystitis. Identification of acrolein as the causative agent, Biochem Pharmacol, 28, 2045, 10.1016/0006-2952(79)90222-3 Crabtree, 1980, Mechanism of glucocorticoid-induced immunosuppression: inhibitory effects on expression of Fc receptors and production of T cell growth factor, J Steroids Biochem, 12, 445, 10.1016/0022-4731(80)90305-2 Dantchev, 1979, Electron microscopic studies of golden hemostatics with Adriamycin, doxorubicin, Cancer Treat Rep, 63, 875 Ettinger, 1982, Pharmacokinetics and biochemical effects of a fatal intrathecal methotrexate overdose, Cancer, 50, 444, 10.1002/1097-0142(19820801)50:3<444::AID-CNCR2820500311>3.0.CO;2-# Gonzalez, 1982, Life-threatening hypocalcemia and hypomagnesium associated with cisplatin chemotherapy, Obstet Gynecol, 59, 732 Green, 1987, ICRF-159 prevents doxorubicin cardio toxicity: results of randomed trial, Proc Am Soc Clin One Abs, 104, 28 Gutterman, 1980, Leukocyte interferon-induced tumor regression in human metastatic breast cancer, multiple myeloma, and malignant lymphoma, Ann Intern Med, 93, 399, 10.7326/0003-4819-93-3-399 Hoffman, 1978, Haenimerling induction and immunological properties of tumor necrosis factor, J Reticuloendothelial Soc, 23, 307 Hoffman M, Mittelman A, Dworkin B, et al: Severe intraphepatic cholestasis in patients treated with recombinant interleukin-2 and lymphokine activated killer cells (in press) Honigsberger, 1983, Neurological effects of recombinant human interferons, Br Med J, 286, 719, 10.1136/bmj.286.6366.719-a Krown, 1987, High dose human lymphoblastoid interferon in metastatic colorectal cancer: Responses, Cancer Treat Rep, 71, 39 Kurzrock, 1985, Pharmacokinetics, single-dose tolerance and biological activity of recombinant gamma interferon in cancer patients, Cancer Res, 45, 2866 Lampidis, 1981, Interferon inhibits cardiac cell function in vitro (41043), Proc Soc Exp Biol Med, 166, 181, 10.3181/00379727-166-41043 LeRoy, 1979, Pharmacokinetic studies of cis-dichlordiammine platinum in the beagle dog: Thermodynamic and kinetic behavoir of DDP in biological milieu, Cancer Treat Rep, 63, 59 Lotze, 1985, In vivo administration of purified human interleukin-2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL-2, J Immunol, 135, 2865, 10.4049/jimmunol.135.4.2865 Lotze, 1986, High-dose recombinant interleukin-2 in the treatment of patients with disseminated cancer. Responses, treatment related morbidity and histologic finding, JAMA, 256, 3117, 10.1001/jama.1986.03380220083027 Lotze, 1986, Clinical effects and toxicity of interleukin-2 in patients with cancer, Cancer, 58, 2764, 10.1002/1097-0142(19861215)58:12<2764::AID-CNCR2820581235>3.0.CO;2-Z Mangan, 1983, Interferon-induced aplasia: Evidence for T-cellmediated suppression of hematopoiesis and recovery after treatment with horse antihuman thymocytes globulin, Am J Hematol, 19, 401, 10.1002/ajh.2830190411 Mattson, 1983, Neurotoxicity of interferon, Cancer Treat Rep, 67, 958 McLaughlin, 1987, Immune thrombocytopenia following alphainterferon in patients with cancer, JAMA, 254, 1353, 10.1001/jama.1985.03360100103022 Mitsudo, 1984, BCNU (1,3-Bis (2-chlorethyl)-l-nitrosourea) lung drug-induced pulmonary changes, Cancer, 54, 751, 10.1002/1097-0142(1984)54:4<751::AID-CNCR2820540427>3.0.CO;2-U Mittleman A, Savona S, Gafney E, et al: Treatment of patients with advanced cancer using long-term cultured lymphokine activated killer (LAK) cells plus recombinant human interleukin-2 (paper submitted) Norrell, 1974, Leukoencephalopathy following the administration of methotrexate into the cerebrospinal fluid in the treatment of primary brain tumors, Cancer, 33, 923, 10.1002/1097-0142(197404)33:4<923::AID-CNCR2820330406>3.0.CO;2-Z Patel, 1976, Cyclophosphamide therapy and interstitial pulmonary fibrosis, Cancer, 38, 1542, 10.1002/1097-0142(197610)38:4<1542::AID-CNCR2820380416>3.0.CO;2-R Phillips, 1983, Intensive 1,3-Bis (2-chloroethyl) 1-nitrosurea (BCNU) NSC #4366650 and cryopreserved autologous marrow transplantation for refractory cancer, A Phase III study, Cancer, 52, 1792, 10.1002/1097-0142(19831115)52:10<1792::AID-CNCR2820521006>3.0.CO;2-D Pilgram, 1972, Stereochemistry of interaction: Interaction of daunomycin with DNA, Nature (New Biol), 235, 17, 10.1038/newbio235017a0 Pokedly, 1979, Prophylactic CNS therapy in childhood acute #3 leukemia, Review of methods used. Am J Pediatr Hematol Oncol, 1, 1119 Quesada, 1984, Alpha interferon for induction of remission in hairy cell leukemia, N Engl J Med, 310, 15, 10.1056/NEJM198401053100104 Rinehart, 1986, Phase I/II trials of human recombinant B-interferon in patients with renal cell carcinoma, Cancer Res, 46, 5364 Rohantiner, 1983, Central nervous system toxicity of interferon, Br J Cancer, 47, 419, 10.1038/bjc.1983.63 Rosenberg, 1977, Passive immunotherapy of cancer in animals and man, Adv Cancer Res, 23, 323, 10.1016/S0065-230X(08)60637-5 Rosenberg, 1984, Adoptive immunotherapy of cancer: Accomplishments and prospects, Cancer Treat Rep, 68, 233 Rosenberg, 1985, Observations on the systemic administration of autologous lymphokine activated killer cells and recombinant interleukin-2 to patients with metastatic cancer, N Engl J Med, 313, 1485, 10.1056/NEJM198512053132327 Rosenberg, 1986, Results of clinical trials with the administration of interleukin-2 and adoptive immunotherapy with activated cells in patients with cancer, Immunobiology, 1721, 420 Rosenberg, 1986, A new approach to the therapy of cancer based on the systemic administration of autologous lymphokine activated killer cells and recombinant interleukin-2, Surgery, 100, 262 Rosenberg, 1987, A progress report on the treatment of 157 patients with advanced cancer using lymphokine activated killer cells and interleukin-2 or high-dose interleukin-2 alone, N Engl J Med, 316, 889, 10.1056/NEJM198704093161501 Ryan, 1981, Pulmonary fibrosis. A complication of 1,3-Bis (2-chlorethyl)-l-nitrosourea (BCNU) therapy, Cancer, 48, 909, 10.1002/1097-0142(19810815)48:4<909::AID-CNCR2820480408>3.0.CO;2-6 Sherwin, 1982, A multiple-dose phase I trial of recombinant leukocyte A interferon in cancer patients, JAMA, 248, 2461, 10.1001/jama.1982.03330190025025 Skills, 1969, Experimental magnesium depletion, Medicine, 48, 61, 10.1097/00005792-196901000-00003 Spector, 1979, Early onset, cyclophosphamide-induced interstitial pneumonitis, JAMA, 242, 2852, 10.1001/jama.1979.03300260022020 Steward, 1981 Thompson, 1971, 535 Tong, 1979, Adriamycin analogues: Synthesis of n-alkylated anthracyclines with enhanced efficacy and reduced cardiotoxity, J Med Chem, 22, 912, 10.1021/jm00194a005 Trump, 1987, High-dose lymphoblastoid interferon in advanced renal cell carcinoma, An eastern-cooperative oncology group study. Cancer Treat Rep, 71, 165 Vetto, 1980, Reduction of toxicity of interleukin-2 and lymphokine activated killer cell in humans by the administration of corticosteroids, J Clin Oncol, 5, 496, 10.1200/JCO.1987.5.3.496 Weinstein, 1986, Pulmonary toxicity of carmustine in patients treated for malignant glioma, Cancer Treat Rep, 70, 943 Weiss, 1981, Hypersensitivity reactions to cancer chemotherapeutic agents, Ann Intern Med, 94, 66, 10.7326/0003-4819-94-1-66 Werkheiser, 1963, The biochemical, cellular and pharmacological action and effects of the folic acid antagonists, Cancer Res, 23, 1277 West, 1987, Constant infusion recombinant interleukin-2 in adoptive immunotherapy of advanced cancer, N Engl J Med, 316, 898, 10.1056/NEJM198704093161502 Wollner, 1979, Non-Hodgkins lymphoma in children: A comparative study of two modalities of therapy, Cancer, 37, 123, 10.1002/1097-0142(197601)37:1<123::AID-CNCR2820370119>3.0.CO;2-7