Histochemical detection of apoptosis in Parkinson's disease

Burns, 1983, A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, 80, 4546 Carson, 1993, Apoptosis and disease, Lancet, 341, 1251, 10.1016/0140-6736(93)91154-E Chiba, 1984, Metabolism of the neurotoxic teritially amine, MPTP, by brain monoamine oxidase, Biochem Biophys Res Commun., 120, 574, 10.1016/0006-291X(84)91293-2 Chiba, 1985, Active uptake of MPP+, metabolite of MPTP, by brain synaptosomes, Biochem Biphys Res Commun., 129, 1228, 10.1016/0006-291X(85)91071-X Dragunow, 1995, In situ evidence for DNA fragmentation in Huntington's disease striatum and Alzheimer's disease temporal lobe, Neuro Report, 6, 1053 Gavrieli, 1992, Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation, J Cell Biol., 119, 493, 10.1083/jcb.119.3.493 Gold, 1993, Detection of DNA fragmentation in apoptosis: Application of in situ nick translation to cell culture systems and tissue sections, J. Histochem. Cytochem., 41, 1023, 10.1177/41.7.8515045 Gold, 1994, Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques, Lab. Invest., 71, 219 Hattori, 1991, Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in Parkinson's disease, Ann. Neurol., 130, 563, 10.1002/ana.410300409 Ikebe, 1990, Increase of deleted mitochondrial DNA in the striatum in Parkinson's disease and senescence, Biochem Biophys Res Commum., 170, 1044, 10.1016/0006-291X(90)90497-B Ikebe, 1995, Point mutations of mitochondrial genome in Parkinson's disease, Mol. Brain Res, 28, 281, 10.1016/0169-328X(94)00209-W Langston, 1984, 1-methyl-4-phenyl-pyridinium ion (MPP+): identification of a metabolite of MPTP, a toxin selective to the substantia nigra, Neurosci Lett., 48, 87, 10.1016/0304-3940(84)90293-3 Lassmann, 1995, Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ, Acta. Neuropathol., 89, 35, 10.1007/BF00294257 Mizuno, 1987, Effects of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain, J Neurochem., 48, 1787, 10.1111/j.1471-4159.1987.tb05737.x Mochizuki, 1993, Iron-melanin complex is toxic to dopaminergic neurons in a nigrostriatal co-culture, Neurodegeneration, 2, 2 Mochizuki, 1994, Apoptosis is induced by 1-methyl-4-phenylpyridinium ion (MPP+) in a ventral mesencephalic-striatal co-culture in rat, Neurosci Lett., 170, 191, 10.1016/0304-3940(94)90271-2 Nishi, 1994, Neurotoxicities of 1-methyl-4-phenylpyridinium ion (MPP+) and tetrahydroisoquinoline derivates on dopaminergic neurons in ventral mesencephalic-striatal co-culture, Neurodegeneration, 3, 33 Schapira, 1989, Mitochondrial complex I deficiency in Parkinson's disese, Lancet, i, 1269, 10.1016/S0140-6736(89)92366-0 Wolvetang, 1994, Mitochondrial respiraory chain inhibitors induce apoptosis, FEBS Lett., 339, 40, 10.1016/0014-5793(94)80380-3 Ziv, 1994, Dopamine induces apoptosis-like cell death in cultured chick sympathetic neurons — a possible novel pathogetic mechanism in Parkinson's disease, Neurosci. Lett., 170, 136, 10.1016/0304-3940(94)90258-5