The inflammasome, autoinflammatory diseases, and gout

Galon, 2000, TNFRSF1A mutations and autoinflammatory syndromes, Curr Opin Immunol, 12, 479, 10.1016/S0952-7915(00)00124-2 McDermott, 1999, Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes, Cell, 97, 133, 10.1016/S0092-8674(00)80721-7 McGonagle, 2006, A proposed classification of the immunological diseases, PLoS Med, 3, e297, 10.1371/journal.pmed.0030297 Stojanov, 2005, Familial autoinflammatory diseases: genetics, pathogenesis and treatment, Curr Opin Rheumatol, 17, 586, 10.1097/bor.0000174210.78449.6b Nemunaitis, 1994, Phase I study of recombinant human interleukin-1 beta (rhIL-1 beta) in patients with bone marrow failure, Bone Marrow Transplant, 14, 583 Nemunaitis, 1994, Phase I study of recombinant interleukin-1 beta in patients undergoing autologous bone marrow transplant for acute myelogenous leukemia, Blood, 83, 3473, 10.1182/blood.V83.12.3473.3473 Crown, 1993, Interleukin-1: biological effects in human hematopoiesis, Leuk Lymphoma, 9, 433, 10.3109/10428199309145750 McKean, 1985, The role of IL 1 in the antigen-specific activation of murine class II-restricted T lymphocyte clones, J Immunol, 135, 3205, 10.4049/jimmunol.135.5.3205 Tamaru, 1998, Interleukin-1beta induces tissue- and cell type-specific expression of adhesion molecules in vivo, Arterioscler Thromb Vasc Biol, 18, 1292, 10.1161/01.ATV.18.8.1292 Sutton, 1997, Endothelial structural integrity is maintained during endotoxic shock in an interleukin-1 type 1 receptor knockout mouse, Shock, 7, 105, 10.1097/00024382-199702000-00006 Furie, 1989, Migration of neutrophils across endothelial monolayers is stimulated by treatment of the monolayers with interleukin-1 or tumor necrosis factor-alpha, J Immunol, 143, 3309, 10.4049/jimmunol.143.10.3309 Dinarello, 2005, Interleukin-1beta, Crit Care Med, 33, S460, 10.1097/01.CCM.0000185500.11080.91 Feng, 1995, Involvement of reactive oxygen intermediates in cyclooxygenase-2 expression induced by interleukin-1, tumor necrosis factor-alpha, and lipopolysaccharide, J Clin Invest, 95, 1669, 10.1172/JCI117842 Pang, 1997, Effect of interleukin-1 beta, tumour necrosis factor-alpha and interferon-gamma on the induction of cyclo-oxygenase-2 in cultured human airway smooth muscle cells, Br J Pharmacol, 121, 579, 10.1038/sj.bjp.0701152 Dinarello, 2002, The IL-1 family and inflammatory diseases, Clin Exp Rheumatol, 20, S1 Campbell, 1988, Recombinant human interleukin-1 stimulates human articular cartilage to undergo resorption and human chondrocytes to produce both tissue- and urokinase-type plasminogen activator, Biochim Biophys Acta, 967, 183, 10.1016/0304-4165(88)90008-6 Dayer, 1986, Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells, J Clin Invest, 77, 645, 10.1172/JCI112350 Verbruggen, 2006, Chondroprotective drugs in degenerative joint diseases, Rheumatology (Oxford), 45, 129, 10.1093/rheumatology/kei171 Kostura, 1989, Identification of a monocyte specific pre-interleukin 1 beta convertase activity, Proc Natl Acad Sci U S A, 86, 5227, 10.1073/pnas.86.14.5227 Watanabe, 2007, Activation of the IL-1b-processing inflammasome is involved in contact hypersensitivity, J Invest Dermatol, 10.1038/sj.jid.5700819 Black, 1989, Activation of interleukin-1 beta by a co-induced protease, FEBS Lett, 247, 386, 10.1016/0014-5793(89)81376-6 Thornberry, 1991, Mechanism-based inactivation of alanine racemase by 3-halovinylglycines, J Biol Chem, 266, 21657, 10.1016/S0021-9258(18)54687-1 Dinarello, 2003, Interleukin-18 and host defense against infection, J Infect Dis, 187, S370, 10.1086/374751 Schmitz, 2005, IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines, Immunity, 23, 479, 10.1016/j.immuni.2005.09.015 Martinon, 2007, Inflammatory caspases and inflammasomes: master switches of inflammation, Cell Death Differ, 14, 10, 10.1038/sj.cdd.4402038 Vasilakos, 1995, IL-1 beta converting enzyme (ICE) is not required for apoptosis induced by lymphokine deprivation in an IL-2-dependent T cell line, J Immunol, 155, 3433, 10.4049/jimmunol.155.7.3433 Li, 1995, Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock, Cell, 80, 401, 10.1016/0092-8674(95)90490-5 Kuida, 1995, Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme, Science, 267, 2000, 10.1126/science.7535475 Martinon, 2002, The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta, Mol Cell, 10, 417, 10.1016/S1097-2765(02)00599-3 Tschopp, 2003, NALPs: a novel protein family involved in inflammation, Nat Rev Mol Cell Biol, 4, 95, 10.1038/nrm1019 Agostini, 2004, NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle–Wells autoinflammatory disorder, Immunity, 20, 319, 10.1016/S1074-7613(04)00046-9 Sutterwala, 2006, Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1, Immunity, 24, 317, 10.1016/j.immuni.2006.02.004 Mariathasan, 2006, Cryopyrin activates the inflammasome in response to toxins and ATP, Nature, 40, 228, 10.1038/nature04515 Kanneganti, 2006, Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3, Nature, 440, 233, 10.1038/nature04517 Kastner, 2005, Hereditary periodic Fever syndromes, Hematology Am Soc Hematol Educ Program, 74, 10.1182/asheducation-2005.1.74 Masters, 2006, Recent advances in the molecular pathogenesis of hereditary recurrent fevers, Curr Opin Allergy Clin Immunol, 6, 428, 10.1097/ACI.0b013e3280109b57 Prieur, 1987, A chronic, infantile, neurological, cutaneous and articular (CINCA) syndrome. A specific entity analysed in 30 patients, Scand J Rheumatol Suppl, 66, 57, 10.3109/03009748709102523 Feldmann, 2002, Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes, Am J Hum Genet, 71, 198, 10.1086/341357 Hoffman, 2001, Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle–Wells syndrome, Nat Genet, 29, 301, 10.1038/ng756 Mikuls, 2006, New insights into gout epidemiology, Curr Opin Rheumatol, 18, 199, 10.1097/01.bor.0000209435.89720.7c Wu, 1989, Urate oxidase: primary structure and evolutionary implications, Proc Natl Acad Sci U S A, 86, 9412, 10.1073/pnas.86.23.9412 Wu, 1992, Two independent mutational events in the loss of urate oxidase during hominoid evolution, J Mol Evol, 34, 78, 10.1007/BF00163854 Choi, 2005, Gout: epidemiology and lifestyle choices, Curr Opin Rheumatol, 17, 341 Choi, 2005, Obesity, weight change, hypertension, diuretic use, and risk of gout in men: the health professionals follow-up study, Arch Intern Med, 165, 742, 10.1001/archinte.165.7.742 Terkeltaub, 1991, Monocyte-derived neutrophil chemotactic factor/interleukin-8 is a potential mediator of crystal-induced inflammation, Arthritis Rheum, 34, 894, 10.1002/art.1780340716 Hachicha, 1995, Inflammatory microcrystals differentially regulate the secretion of macrophage inflammatory protein 1 and interleukin 8 by human neutrophils: a possible mechanism of neutrophil recruitment to sites of inflammation in synovitis, J Exp Med, 182, 2019, 10.1084/jem.182.6.2019 di Giovine, 1991, Urate crystals stimulate production of tumor necrosis factor alpha from human blood monocytes and synovial cells. Cytokine mRNA and protein kinetics, and cellular distribution, J Clin Invest, 87, 1375, 10.1172/JCI115142 Niel, 2006, Colchicine today, Joint Bone Spine, 73, 672, 10.1016/j.jbspin.2006.03.006 Shi, 2003, Molecular identification of a danger signal that alerts the immune system to dying cells, Nature, 425, 516, 10.1038/nature01991 Martinon, 2006, Gout-associated uric acid crystals activate the NALP3 inflammasome, Nature, 440, 237, 10.1038/nature04516 Martinon, 2006, Gout: new insights into an old disease, J Clin Invest, 116, 2073, 10.1172/JCI29404 Chen, 2006, MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals, J Clin Invest, 116, 2262, 10.1172/JCI28075 Hoffman, 2004, Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist, Lancet, 364, 1779, 10.1016/S0140-6736(04)17401-1 Hawkins, 2004, Spectrum of clinical features in Muckle–Wells syndrome and response to anakinra, Arthritis Rheum, 50, 607, 10.1002/art.20033 Hawkins, 2003, Interleukin-1-receptor antagonist in the Muckle–Wells syndrome, N Engl J Med, 348, 2583, 10.1056/NEJM200306193482523 So, 2007, A pilot study of IL-1 inhibition by anakinra in acute gout, Arthritis Res Ther, 9, R28, 10.1186/ar2143