1Department of Medicine and Cancer Center, University of California, San Diego, USA
2Department of Chemistry and Biochemistry, University of California, San Diego, USA
3The Berkeley Center for Structural Biology, Lawrence Berkeley National Laboratory, Berkeley, USA
4Genomics Institute of the Novartis Research Foundation, San Diego, USA
5Howard Hughes Medical Institute, University of California, San Diego, USA
6Department of Pharmacology, University of California, San Diego, USA
7Department of Pharmacology, Baylor College of Medicine, Houston, USA