Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus

Cell - Tập 182 Số 4 - Trang 812-827.e19 - 2020
Bette Korber1,2, Will Fischer2, S. Gnanakaran2, Hyejin Yoon2, James Theiler2, W. P. Abfalterer2, Nicolas Hengartner2, Elena E. Giorgi2, Tanmoy Bhattacharya2, Brian Foley2, Kathryn M. Hastie3, Matthew Parker4, David G. Partridge5, Cariad Evans5, Timothy M. Freeman4, Thushan I. de Silva6,5, Charlene McDanal7, Lautaro G. Perez7, Haili Tang7, Alex Moon-Walker8,3,9, Sean P. J. Whelan8, Celia C. LaBranche7, Alexander J. Keeley3, Benjamin B. Lindsey7, Paul J. Parsons, Rebecca Brown, Laura Carrilero, Luke R. Green, Danielle C. Groves, Dennis Wang, Mohammad Raza, Darren Smith, Rachel Tucker, Matthew D. Wyles4
1New Mexico Consortium, Los Alamos, NM 87545, USA
2Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, NM 87545, USA
3La Jolla Institute for Immunology, La Jolla, CA 92037, USA
4Sheffield Biomedical Research Centre & Sheffield Bioinformatics Core, University of Sheffield, Sheffield S10 2HQ, UK
5Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield S10 2JF, UK
6Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, S10 2RX, UK
7Duke Human Vaccine Institute & Department of Surgery, Durham, NC 27710, USA
8Department of Molecular Microbiology, Washington University in Saint Louis, St. Louis, MO 63130, USA
9Program in Virology, Harvard University, Boston, MA 02115, USA

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