Hypoxia Due to Cardiac Arrest Induces a Time-Dependent Increase in Serum Amyloid β Levels in Humans

PLoS ONE - Tập 6 Số 12 - Trang e28263
Henrik Zetterberg1, Erik Mörtberg2, Linan Song3, Lei Chang3, Gail K Provuncher3, Purvish Patel3, Evan P. Ferrell3, David R. Fournier3, Cheuk W. Kan3, Todd Campbell3, Ray E. Meyer3, Andrew J. Rivnak3, Brian Pink3, Kaitlin Minnehan3, Tomasz Piech3, David M. Rissin3, David C. Duffy3, Sten Rubertsson2, David H. Wilson3, Kaj Blennow1
1Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden
2Department of Surgical Sciences, Anaesthesia and Intensive Care, Uppsala University, Uppsala, Sweden
3Quanterix Corporation, Cambridge, Massachusetts, United States of America

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K Blennow, 2006, Alzheimer's disease., Lancet, 368, 387, 10.1016/S0140-6736(06)69113-7

L Bertram, 2010, The genetics of Alzheimer disease: back to the future., Neuron, 68, 270, 10.1016/j.neuron.2010.10.013

B Hooshmand, 2010, Homocysteine and holotranscobalamin and the risk of Alzheimer disease: a longitudinal study., Neurology, 75, 1408, 10.1212/WNL.0b013e3181f88162

J Li, 2011, Vascular risk factors promote conversion from mild cognitive impairment to Alzheimer disease., Neurology, 76, 1485, 10.1212/WNL.0b013e318217e7a4

A Solomon, 2009, Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later., Dement Geriatr Cogn Disord, 28, 75, 10.1159/000231980

X Guo, 2009, Blood pressure components and changes in relation to white matter lesions: a 32-year prospective population study., Hypertension, 54, 57, 10.1161/HYPERTENSIONAHA.109.129700

MA Koike, 2010, Oligemic hypoperfusion differentially affects tau and amyloid-{beta}., Am J Pathol, 177, 300, 10.2353/ajpath.2010.090750

M Guglielmotto, 2009, The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha., J Neurochem, 108, 1045, 10.1111/j.1471-4159.2008.05858.x

X Wang, 2010, Cerebrovascular hypoperfusion induces spatial memory impairment, synaptic changes, and amyloid-beta oligomerization in rats., J Alzheimers Dis, 21, 813, 10.3233/JAD-2010-100216

JP Qi, 2007, Cerebral ischemia and Alzheimer's disease: the expression of amyloid-beta and apolipoprotein E in human hippocampus., J Alzheimers Dis, 12, 335, 10.3233/JAD-2007-12406

HM Wisniewski, 1996, Beta-protein immunoreactivity in the human brain after cardiac arrest., Folia Neuropathol, 34, 65

DM Rissin, 2011, Simultaneous detection of single molecules and singulated ensembles of molecules enables immunoassays with broad dynamic range., Anal Chem, 83, 2279, 10.1021/ac103161b

DM Rissin, 2010, Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations., Nat Biotechnol, 28, 595, 10.1038/nbt.1641

E Mortberg, 2011, S-100B is superior to NSE, BDNF and GFAP in predicting outcome of resuscitation from cardiac arrest with hypothermia treatment., Resuscitation, 82, 26, 10.1016/j.resuscitation.2010.10.011

B Jennett, 1975, Assessment of outcome after severe brain damage., Lancet, 1, 480, 10.1016/S0140-6736(75)92830-5

RO Cummins, 1997, Recommended guidelines for reviewing, reporting, and conducting research on in-hospital resuscitation: the in-hospital ‘Utstein style’. A statement for healthcare professionals from the American Heart Association, the European Resuscitation Council, the Heart and Stroke Foundation of Canada, the Australian Resuscitation Council, and the Resuscitation Councils of Southern Africa., Resuscitation, 34, 151

M Bjerke, 2010, Confounding factors influencing amyloid Beta concentration in cerebrospinal fluid., Int J Alzheimers Dis 2010, pii, 986310

MD Kirkitadze, 2001, Identification and characterization of key kinetic intermediates in amyloid beta-protein fibrillogenesis., J Mol Biol, 312, 1103, 10.1006/jmbi.2001.4970

M Guo, 2005, Charge substitution shows that repulsive electrostatic interactions impede the oligomerization of Alzheimer amyloid peptides., FEBS Lett, 579, 3574, 10.1016/j.febslet.2005.05.036

H LeVine 3rd, 1993, Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution., Protein Sci, 2, 404, 10.1002/pro.5560020312

K Yaffe, 2011, Sleep-disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older women., Jama, 306, 613

OI Okereke, 2009, Performance characteristics of plasma amyloid-beta 40 and 42 assays., J Alzheimers Dis, 16, 277, 10.3233/JAD-2009-0948

H Vanderstichele, 2000, Standardization of measurement of beta-amyloid(1–42) in cerebrospinal fluid and plasma., Amyloid, 7, 245, 10.3109/13506120009146438

PD Mehta, 2000, Plasma and cerebrospinal fluid levels of amyloid beta proteins 1–40 and 1–42 in Alzheimer disease., Arch Neurol, 57, 100, 10.1001/archneur.57.1.100

O Hansson, 2010, Evaluation of plasma Abeta(40) and Abeta(42) as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment., Neurobiol Aging, 31, 357, 10.1016/j.neurobiolaging.2008.03.027