The relationship between spinal trabecular bone mineral content and iliac crest trabecular bone volume
Tóm tắt
The relationship between spinal trabecular bone mineral density and iliac crest trabecular bone volume has been studied in 84 patients, 23 with primary osteoporosis, 19 with osteoporosis secondary to inflammatory bowel disease, and 42 with nonsteroid-treated rheumatoid arthritis. Spinal trabecular bone mineral density was measured in the first three lumbar vertebrae by quantitative computed tomography, and iliac crest trabecular bone volume was assessed histomorphometrically in sections from trans-iliac biopsies using computerized techniques. In all 84 patients, there was a significant positive correlation between the two measurements (r=0.60,P<0.001). However, when the three patient groups were analyzed separately, a significant correlation was found in the group with secondary osteoporosis (r=0.65,P<0.01) but not in the patients with primary osteoporosis (r=0.07) or rheumatoid arthritis (r=0.19). These results indicate that the relationship between spinal trabecular bone mineral density and iliac crest trabecular bone volume differs according to the underlying disease process, these differences possibly reflecting variations in skeletal patterns of bone loss in different types of osteoporosis.
Tài liệu tham khảo
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