Conformational changes induced in antipoly(l-prolyl) antibodies by oligoproline haptens of different sizes

Borsos, 1965, Complement fixation on cell surfaces by 19S and 7S antibodies, Science, 150, 505, 10.1126/science.150.3695.505 Bovey, 1967, Circular dichroism spectrum poly-l-proline, Biopolymers, 5, 325, 10.1002/bip.1967.360050310 Carver, 1966, Analysis of the optical rotatory disperion of polypeptides and proteins. IV. A digital computer analysis for the region 190–600 mμ, J. Am. Chem. Soc., 88, 2550, 10.1021/ja00963a034 Deber, 1970, Nuclear magnetic resonance evidence for cis-peptide bonds in proline oligomers, J. Am. chem. Soc., 92, 6191, 10.1021/ja00724a016 Denk, 1974, Influence ol 2-mercaptoethanol(2-ME) treatment of IgG antibody on its ability to induce cytotoxicity in nonsensitized lymphocytes, Cell Immunol., 13, 489, 10.1016/0008-8749(74)90268-8 Engel, 1966, Polymers of tripeptides as collagen models. II. Conformational changes ol poly(l-prolyl-glycyl-l-prolyl) solution, J. molec Boil., 17, 255, 10.1016/S0022-2836(66)80106-7 Fruchter, 1965, Preparation and properties of two active forms of ribonuclease, J. biol. Chem., 240, 3868, 10.1016/S0021-9258(18)97123-1 Gurari, 1973, Antigenicity of dinilrophenyl polyproline, Eur. J. Immun., 3, 196, 10.1002/eji.1830030404 Haselkorn, 1974, Kinetic mapping of the antibody combining site by chemical relaxation spectrometry, Biochemistry, 13, 2210, 10.1021/bi00707a030 Herbert, 1973, Passive haemagglutination with special reference to the tanned cell technique, 20.1 Herskovitz, 1967, Difference spectroscopy, Vol. 11, 748 Holowka, 1972, Changes in intrinsic circular dichroism of several homogenous anti-type III pneumococcal antibodies on binding of a small hapten, 69, 3399 Hoyer, 1968, Heterogeneity of rabbit IgM antibody as detected by C'la fixation, J. exp. Med., 127, 589, 10.1084/jem.127.3.589 Hyslop, 1970, Fixation of complement and the activated first component (Cl) of complement by complexes formed between antibody and divalent hapten, J. exp. Med., 131, 783, 10.1084/jem.131.4.783 Koshland, 1966, Comparison of experimental binding data and theoretical models in proteins containing subunits, Biochemistry, 5, 365, 10.1021/bi00865a047 Kurtz, 1956, Mutarotalion of poly-l-proline, Nature, 178, 1066, 10.1038/1781066a0 Levine, 1973, Micro-complement fixation, 22.1 Metzger, 1974, Effect ol antigen binding on the properties of antibody, Adv. Immunol., 18, 169, 10.1016/S0065-2776(08)60310-7 Monod, 1965, On the nature of allosteric transitions: A plausible model, J. molec. Biol., 12, 88, 10.1016/S0022-2836(65)80285-6 Parker, 1973, Spectrofluorometric methods, 14.1 Pilz, 1973, Shape and volume of anti-poly(d-alanyl) antibodies in the presence and absence of tetra-d-alanine as followed by small-angle X-ray scattering, Biochemistry, 12, 4998, 10.1021/bi00748a028 Pilz, 1975, Shape and volume of fragments Fab and (Fab)2 of anti-poly(d-alanyl) antibodies in the presence and absence of tetra-d-alanine as determined by small-angle X-ray scattering, Biochemistry, 14, 1326, 10.1021/bi00677a035 Pollet, 1974, Changes in optical parameters of myeloma proteins with phosphorylcholine binding, J. biol. Chem., 249, 5188, 10.1016/S0021-9258(19)42346-6 Porath, 1967, Chemical coupling of proteins to agarose, Nature, 215, 1491, 10.1038/2151491a0 Porter, 1959, The hydrolysis of rabbit globulins and antibodies with crystalline papain, Biochem. J., 73, 119, 10.1042/bj0730119 Schechter, 1966, Combining sites of antibodies with l-alanine and d-alanine peptide specificity and the effect of serum proteolytic activity on their estimation, Biochim. Biophys. Acta, 127, 438, 10.1016/0304-4165(66)90398-9 Schlessinger, 1975, Antigen-induced conformational changes in antibodies and their Fab fragments studied by circular polarization of fluorescence, 72, 2775 Schur, 1964, The role of disulfide bonds in the complement-fixing and precipitating properties of 7S rabbit and sheep antibodies, J. exp. Med., 120, 531, 10.1084/jem.120.4.531 Sears, 1973, Circular dichroism, 445 Sela, 1967, Conformational determinants, 32, 537 Troll, 1955, A photometric method for the determination of proline, J. biol. Chem., 215, 655, 10.1016/S0021-9258(18)65988-5