Carbon monoxide inhalation ameliorates cold ischemia/reperfusion injury after rat liver transplantation

Maines, 1974, Cobalt induction of hepatic heme oxygenase; with evidence that cytochrome P-450 is not essential for this enzyme activity, Proc Natl Acad Sci U S A, 71, 4293, 10.1073/pnas.71.11.4293 Otterbein, 2000, Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway, Nat Med, 6, 422, 10.1038/74680 Brouard, 2000, Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis, J Exp Med, 192, 1015, 10.1084/jem.192.7.1015 Fujita, 2001, Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis, Nat Med, 7, 598, 10.1038/87929 Nakao, 2004, Biliverdin protects the functional integrity of a transplanted syngeneic small bowel, Gastroenterology, 127, 595, 10.1053/j.gastro.2004.05.059 Stocker, 1987, Bilirubin is an antioxidant of possible physiological importance, Science, 235, 1043, 10.1126/science.3029864 Baranano, 2002, Biliverdin reductase: a major physiologic cytoprotectant, Proc Natl Acad Sci U S A, 99, 16093, 10.1073/pnas.252626999 Jeney, 2002, Pro-oxidant and cytotoxic effects of circulating heme, Blood, 100, 879, 10.1182/blood.V100.3.879 Akamatsu, 2004, Heme oxygenase-1-derived carbon monoxide protects hearts from transplant associated ischemia reperfusion injury, Faseb J, 18, 771, 10.1096/fj.03-0921fje Fujimoto, 2004, Carbon monoxide protects against cardiac ischemia—reperfusion injury in vivo via MAPK and Akt—eNOS pathways, Arterioscler Thromb Vasc Biol, 24, 1848, 10.1161/01.ATV.0000142364.85911.0e Lavitrano, 2004, Carbon monoxide improves cardiac energetics and safeguards the heart during reperfusion after cardiopulmonary bypass in pigs, Faseb J, 18, 1093, 10.1096/fj.03-0996fje Zhang, 2003, Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3, J Biol Chem, 278, 1248, 10.1074/jbc.M208419200 Neto, 2004, Protection of transplant-induced renal ischemia-reperfusion injury with carbon monoxide, Am J Physiol Renal Physiol, 287, F979, 10.1152/ajprenal.00158.2004 Nakao, 2003, Carbon monoxide inhalation protects rat intestinal grafts from ischemia/reperfusion injury, Am J Pathol, 163, 1587, 10.1016/S0002-9440(10)63515-8 Dijkstra, 2004, Opposite effect of oxidative stress on inducible nitric oxide synthase and haem oxygenase-1 expression in intestinal inflammation: anti-inflammatory effect of carbon monoxide, J Pathol, 204, 296, 10.1002/path.1656 Zuckerbraun, 2003, Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1, J Exp Med, 198, 1707, 10.1084/jem.20031003 Amersi, 2002, Ex vivo exposure to carbon monoxide prevents hepatic ischemia/reperfusion injury through p38 MAP kinase pathway, Hepatology, 35, 815, 10.1053/jhep.2002.32467 Kamada, 1983, A surgical experience with five hundred thirty liver transplants in the rat, Surgery, 93, 64 Chia, 1998, Adenovirus-mediated gene transfer to liver grafts: an improved method to maximize infectivity, Transplantation, 66, 1545, 10.1097/00007890-199812150-00020 Takahashi, 2002, Role of NF-kappaB on liver cold ischemia-reperfusion injury, Am J Physiol Gastrointest Liver Physiol, 283, G1175, 10.1152/ajpgi.00515.2001 Jaeschke, 1990, Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo, Faseb J, 4, 3355, 10.1096/fasebj.4.15.2253850 Stupfel, 1970, Physiological and biochemical effects on rats and mice exposed to small concentrations of carbon monoxide for long periods, Ann N Y Acad Sci, 174, 342, 10.1111/j.1749-6632.1970.tb49799.x Song, 2003, Carbon monoxide induces cytoprotection in rat orthotopic lung transplantation via anti-inflammatory and anti-apoptotic effects, Am J Pathol, 163, 231, 10.1016/S0002-9440(10)63646-2 Sarady, 2004, Carbon monoxide protection against endotoxic shock involves reciprocal effects on iNOS in the lung and liver, Faseb J, 18, 854, 10.1096/fj.03-0643fje Otterbein, 2003, MKK3 mitogen-activated protein kinase pathway mediates carbon monoxide-induced protection against oxidant-induced lung injury, Am J Pathol, 163, 2555, 10.1016/S0002-9440(10)63610-3 Namura, 2001, Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia, Proc Natl Acad Sci U S A, 98, 11569, 10.1073/pnas.181213498 Alessandrini, 1999, MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia, Proc Natl Acad Sci U S A, 96, 12866, 10.1073/pnas.96.22.12866 Duan, 2004, Anti-inflammatory effects of mitogen-activated protein kinase kinase inhibitor U0126 in an asthma mouse model, J Immunol, 172, 7053, 10.4049/jimmunol.172.11.7053