Tetracycline-based histological analysis of bone remodeling

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Enlow, D. H.: Principles of bone remodeling. Springfield: Ch. C. Thomas 1963.

Epker, B. N., andH. M. Frost: The direction of transverse drift of actively forming osteons in human rib cortex. J. Bone Jt Surg. A47, 1211–1215 (1965a).

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Frost, H. M.: Unpublished observations, 1968.

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Frost, H. M., A. R. Villanueva, andS. Jett, andE. Eyring: Tetracycline-based analysis of bone remodeling in osteopetrosis. Clin. Orthop. (in press) (1969).

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Hattner, R., B. N. Epker, andH. M. Frost Suggested sequential mode of control of changes in cell behavior in adult bone remodeling. Nature (Lond.)206, 489–490 (1965).

Jaworski, Z.: Unpublished work, 1968.

Jee, W. S. S., E. L. Blackwood, N. L. Dockum, R. K. Haslam, andF. A. Kincl: Bioassay of responses of growing bones to cortisol. Clin. Orthop.49, 39–63 (1966).

Jett, S., K. Wu, andH. M. Frost: Tetracycline-based histological measurement of corticalendosteal bone formation in normal and osteoporotic rib. Henry Ford Hosp. Med. J.15, 325–344 (1967).

Johnson, L. C.: Morphologic analysis in pathology: the kinetics of disease and general biology of bone. In: Bone biodynamics, ed.H. M. Frost, p. 543–654. Boston: Little-Brown & Co. 1964.

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—, andJ. Gershon-Cohen: Quantitative microradiographic study of normal and osteoporotic bone. J. Bone Jt Surg. A47, 785–806 (1965).

Landeros, O., andH. M. Frost: Comparison of amounts of remodeling activity in opposite cortices of ribs in children and adults. J. dent. Res.45, 152–158 (1966).

——, andH. M. Frost: A cell system in which the rate and amount of protein synthesis are separately controlled. Science145, 1323–1324 (1964).

Meuniere, P.: Unpublished work, 1968.

Milch, R. A., D. P. Rall, andJ. E. Tobie: Bone localization of the tetracyclines. J. nat. Cancer Inst.19, 87–93 (1957).

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Pirok, D. J., J. R. Ramser, H. Takahashi, A. R. Villanueva, andH. M. Frost: Normal histological, tetracycline and dynamic parameters in human mineralized bone sections. Henry Ford Hosp. med. Bull.14, 195–218 (1966).

Ramser, J. R., A. R. Villanueva, andH. M. Frost: Cortical bone dynamics in osteomalacia, measured by tetracycline bone labeling. Clin. Orthop.49, 89–102 (1966).

Rush, T., D. J. Pirok, andH. M. Frost: Fractional labeling: the fraction of actively forming osteons that take tetracycline labels in normal human bone. Henry Ford Hosp. med. Bull.14, 255–263 (1966).

Santoro, F., andH. M. Frost: Correlation of the transverse sizes of 6th and 11th ribs in normal and osteoporotic individuals. Henry Ford Hosp. med. J.16, 87–96 (1968).

——: Osteoid seams and resorption spaces in standard samples of human 6th and 11th ribs. Henry Ford Hosp. med. J.15, 241–246 (1967).

Sarnsethsiri, P. andO. Hitt: Unpublished work: manuscript in preparation, 1969.

Schen, S., A. R. Villanueva, andH. M. Frost: Number of osteoblasts per unit area of osteoid seam in cortical human bone. Canad. J. Physiol. Pharmacol.43, 319–325 (1965).

Sedlin, E. D.: Uses of bone as a model system in the study of aging. In: Bone biodynamics, ed.H. M. Frost, p. 655–668. Little-Brown & Co. 1964 a.

— The ratio of cortical area to total cross section area in rib diaphysis: a quantitative index of osteoporosis. Clin. Orthop.36, 131–168 (1964b).

Soni, N. N.: Quantitative study of bone activity in alveolar and femoral bone of the guinea pig. J. dent. Res.47, 584–589 (1968).

Takahashi, H., andH. M. Frost: Age and sex related changes in the amount of cortex in normal human ribs. Acta orthop. scand.37, 122–130 (1966).

——: A tetracycline-based evaluation of the relative prevalence and incidence of formation of secondary osteons in human cortical bone. Canad. J. Physiol. Pharmacol.43, 783–800 (1965).

Villanueva, A. R.: An improved stain for fresh mineralized bone sections: useful in the diagnosis of certain metabolic diseases of bone. Amer. J. clin. Path.47, 78–84 (1967).

Wu, K., S. Jett, andH. M. Frost: Bone resorption rates in physiological, senile and postmenopausal osteoporoses. J. Lab. clin. Med.69, 810–818 (1967).

Wu, K., K. E. Schubeck, H. M. Frost, andA. R. Villanueva: Haversian bone formation rates determined by a new method in human diabetes mellitus, osteogenesis imperfecta and osteoporosis, and in a Mastodon. Clin. Orthop. (1969) (in press).

Zeiss, C. (Oberkochen): Integrating Eyepiece Leaflet40 (1958, 1960).