First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in patients with non-small-cell lung cancer (CheckMate 9LA): an international, randomised, open-label, phase 3 trial
Luis Paz-Ares1, Tudor-Eliade Ciuleanu2, Manuel Cobo3, Michael Schenker4, Bogdan Zurawski5, Juliana Menezes6, Eduardo Richardet7, Jaafar Bennouna8, Enriqueta Felip9, Oscar Juan-Vidal10, Aurelia Alexandru11, Hiroshi Sakai12, Alejo Lingua13, Pamela Salman14, Pierre-Jean Souquet15, Pedro De Marchi16, Claudio Martin17, Maurice Pérol18, Arnaud Scherpereel19, Shun Lu20
1Hospital Universitario 12 de Octubre, CNIO-H12o Lung Cancer Unit, Universidad Complutense & CiberOnc, Madrid, Spain
2Institutul Oncologic Prof Dr Ion Chiricuta and UMF Iuliu Hatieganu, Cluj-Napoca, Romania
3Unidad de Gestión Clínica Intercentros de Oncología Médica, Hospitales Universitarios Regional y Virgen de la Victoria, IBIMA, Málaga, Spain
4Sf. Nectarie Oncology Center, Craiova, Romania
5Ambulatorium Chemioterapii, Bydgoszcz, Poland
6Hospital Nossa Senhora da Conceição, Porto Alegre, Brazil
7Instituto Oncológico De Córdoba, Córdoba, Argentina
8Thoracic Oncology Unit, University Hospital of Nantes and INSERM, CRCINA, Nantes, France
9Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona, Spain
10Hospital Universitario la Fe, Valencia, Spain
11Institute of Oncology Prof Dr Alexandru Trestioreanu Bucha, Bucharest, Romania
12Saitama Cancer Center, Saitama, Japan
13Instituto Medico Rio Cuarto SA, Córdoba, Argentina
14Fundacion Arturo Lopez Perez, Santiago, Metropolitana, Chile
15Hôpital Lyon Sud, Lyon, Pierre Bénite, France
16Barretos Cancer Hospital, Barretos, Brazil
17Instituto Alexander Fleming, Buenos Aires, Argentina
18Léon Bérard Cancer Center, Lyon, France
19Pulmonary and Thoracic Oncology, University of Lille, CHU Lille, INSERM U1189, OncoThAI, Lille, France
20Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai JiaoTong University, Shanghai, China
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The Lancet Oncology
Tập 22
198-211
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