Potent Inhibition of Human Telomerase by Nitrostyrene Derivatives

Molecular Pharmacology - Tập 63 Số 5 - Trang 1117-1124 - 2003
Joo‐Hee Kim1, Jun Hyun Kim, Gun Eui Lee, Jong Eun Lee, In Kwon Chung
1DNA Link, Milk Building, Yonsei University, Seoul, Korea.

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Tài liệu tham khảo

10.1038/sj.onc.1204092

10.1038/350569a0

10.1146/annurev.bi.61.070192.000553

10.1016/S0092-8674(01)80006-4

10.1126/science.279.5349.349

10.1016/0014-5793(71)80092-3

10.1038/nm1197-1271

Bryan, 1995, Telomere elongation in immortal human cells without detectable telomerase activity., EMBO (Eur Mol Biol Organ) J, 14, 4240, 10.1002/j.1460-2075.1995.tb00098.x

10.1081/IPH-120003749

10.1038/sj.onc.1205063

Counter, 1992, Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity., EMBO (Eur Mol Biol Organ) J, 11, 1921, 10.1002/j.1460-2075.1992.tb05245.x

10.1093/emboj/20.24.6958

10.1124/mol.61.5.1154

10.1124/mol.60.5.981

Grand, 2002, The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivo., Mol Cancer Ther, 1, 565

10.1146/annurev.bi.65.070196.002005

10.1038/13495

10.1016/0921-8734(91)90018-7

10.1038/345458a0

10.1101/SQB.1994.059.01.035

10.1038/346866a0

10.1021/bi982829k

10.1073/pnas.96.25.14276

10.1093/jnci/88.2.116

Izbicka, 1999, Effects of cationic porphyrins as G-quadruplex interactive agents in human tumor cells., Cancer Res, 59, 639

10.1124/mol.61.4.879

10.1126/science.7605428

10.1093/nar/25.13.2595

10.1038/23962

10.1038/sj.onc.1203538

10.1126/science.7545310

Mikami, 1991, Antifungal activity of SL-1, a beta-nitrostyrene type pigment and its synthetic congeners., J Antibiot (Tokyo), 44, 1454, 10.7164/antibiotics.44.1454

Naasani, 1999, FJ5002: a potent telomerase inhibitor identified by exploiting the disease-oriented screening program with COMPARE analysis., Cancer Res, 59, 4004

10.1074/jbc.M201266200

10.1021/jm9801105

10.1021/jm990084q

10.1073/pnas.95.20.11549

Shay, 1997, Survey of telomerase activity in human cancer., Eur J Cancer, 33, 777, 10.1016/S0959-8049(97)00062-2

Strahl, 1996, Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines., Mol Cell Biol, 16, 53, 10.1128/MCB.16.1.53

10.1021/jm00112a003

10.1016/S0960-9822(98)70109-5

10.1016/S0167-7799(00)01541-9

10.1101/gad.13.18.2388