Therapeutic implications of iodine-125 cytotoxicity

William D. Bloomer1, William H. McLaughlin1, S. James Adelstein1
1Departments of Radiation Therapy and Radiology, Harvard Medical School, Joint Center for Radiation Therapy and Joint Program in Nuclear Medicine, Boston, MA, USA

Tài liệu tham khảo

Ahnstrom, 1970, On the killing and mutagenic action in E. coli associated with the Auger effect during '251 decay, Mutat. Res., 10, 247, 10.1016/0027-5107(70)90121-1 Anderson, 1972, Oestrogen and nuclear binding sites. Determination of specific sites by (3H) oestradiol exchange, Biochem. J., 126, 561, 10.1042/bj1260561 Bloomer, 1977, 5-125I-lododeoxyuridine as prototype for radionuclide therapy with Auger emitters, Nature, 265, 620, 10.1038/265620a0 Bloomer, 1978, 5-(125I)-lododeoxyuridine and the Auger effect: biological consequences and implications for therapy, Pathobiology A., 8, 407 Bloomer, 1978, 5-(125I)-lododeoxyuridine in experimental tumor therapy!Therapy in Nuclear Medicine, 177 Bloomer, 1981, The role of subcellular localization in assessing the cytotoxicity of iodine-125 labelled iododeoxyuridine, iodotamoxifen, and iodoantipyrine, J. Radioanal. Chem., 65, 209, 10.1007/BF02516105 Bloomer, 1980, Iodine-125-labeled tamoxifen is differentially cytotoxic to cells containing oestrogen receptors, Int. J Radiat. Biol., 38, 197, 10.1080/09553008014551101 Bradley, 1975, The radiotoxicity of iodine-125 in mammalian cells. I. Effects on the survival curve of radioiodine incorporated into DNA, Radiat. Res., 64, 555, 10.2307/3574245 Brooks, 1973, Estrogen receptor in human line (MCF-7) from breast carcinoma, J. Biol. Chem., 248, 6251, 10.1016/S0021-9258(19)43537-0 Burki, 1974, Mammalian cells: Damage in late replicating DNA as the most efficient cause of reproductive death, Exp. Cell. Res., 87, 277, 10.1016/0014-4827(74)90481-9 Burki, 1973, Inactivation of mammalian cells after disintegration of 3H or 125I in cell DNA at –196°C, Int. J. Radial. Biol., 24, 363, 10.1080/09553007314551221 Carlson, 1963, Formation of fragment ions from CH3Te125 and C2H5Te125 following the nuclear decays of CH3I125 and C2H5I125, J. Chem. Phys., 38, 2930, 10.1063/1.1733622 Chan, 1976, The radiotoxicity of iodine-125 in mammalian cells. II. A comparative study on cell survival and cytogenetic responses to 125UdR, 131IUdR and 3HTdR, Radial. Res., 67, 332, 10.2307/3574422 Chariton, 1978, Microdosimetry of radioactive nuclei incorporated into the DNA of mammalian cells, 91 Dewey, 1972, Confirmation of lesions having the potential for forming chromosomal aberrations, Int. J. Radial. Biol., 22, 95, 10.1080/09553007214550821 Dewey, 1971, Chromosomal aberrations and mortality of x-irradiated mammalian cells, 68, 667 Djordjevic, 1960, Genetics of human cell lines. III. Incorporation of 5-bromo and 5-iododeoxyuridine into the deoxyribonucleic acid of human cells and its effects on radiation sensitivity, J. Exptl. Med., 112, 509, 10.1084/jem.112.3.509 Feinendegen, 1971, Biological toxicity associated with the Auger effect, 419 Gorski, 1968, Hormone receptors: Studies in the interaction of estrogen with the uterus, Rec. Prog. Horm. Res., 24, 45 Gurpide, 1971, Quantitative studies of tissue uptake and deposition of hormones, Acta. Endocrinol. (Copenhagen), 153, 247, 10.1530/acta.0.068S247 Gurpide, 1969, Dynamics of uptake of estrogens and androgens by human endometrium. Application of a double-isotope technique, J. Biol. Chem., 244, 5159, 10.1016/S0021-9258(18)63641-5 Halpern, 1977, Chemical and biological consequences of β-decay, Rad. Environ. Biophys., 14, 167, 10.1007/BF01323937 Halpern, 1977, Chemical and biological consequences of β-decay, Rad. Environ. Biophys., 14, 257, 10.1007/BF01325241 Heel, 1978, Tamoxifen: A review of its pharmacological properties and therapeutic use in the treatment of breast cancer, Drugs, 16, 1, 10.2165/00003495-197816010-00001 Hofer, 1971, Radiotoxicity of intranuclear tritium, 125iodine and 131iodine, Radial. Res., 47, 94, 10.2307/3573291 Jensen, 1962, Basic guides to the mechanism of estrogen action, Recent Prog. Horm. Res., 18, 387 Jensen, 1968, A two-step mechanism for the interaction of estradiol with the rat uterus, 59, 632 Katzenellenbogen, 1973, Studies on the uterine cytoplasmic estrogen binding protein. Thermal stability and ligand dissociation rate. An assay of empty and filled sties by exchange, Biochemistry, 12, 4091, 10.1021/bi00745a011 Krisch, 1972, Lethal effects of iodine-125 decay by electron capture in Escherichia coli and in bacteriophage Tl, Int. J. Radial. Biol., 21, 167, 10.1080/09553007214550201 Krisch, 1975, Further studies of DNA damage and lethality from the decay of iodine-125 in bacteriophages, Int. J. Radial. Biol., 27, 553, 10.1080/09553007514550581 Lippman, 1977, In vitro model systems for the study of hormone dependent human breast cancer, N. Engl. J. Med., 296, 154, 10.1056/NEJM197701202960307 Martin, 1977, Induction of double-stranded breaks in DNA by binding with an 125I-labelled acridine, Int. J. Radial. Biol., 32, 491, 10.1080/09553007714551261 Martin, 1979, Cytotoxicity of an '251-labeled DNA-binding compound that induces double-stranded DNA breaks, Cancer Res., 39, 3244 Martin, 1981, Range of radiochemical damage to DNA with decay of iodine-125, Science, 213, 896, 10.1126/science.7256283 Regaud, 1927, La radiosensibilite cellulaire dans ses manifestations generales, Radiophysiologie et Radiotherapie, 1, 104 Sakore, 1977, Mutagennucleic acid intercalative binding: Structure of a 9-aminoacridine: 5-iodocytidyl (3′–5′) guanosine crystalline complex, 74, 188 Schmidt, 1973, The occurrence of double-strand breaks in coliphage Tl-DNA by iodine-125 decay, Int. J. Radial. Biol., 24, 307, 10.1080/09553007314551141 Scott, 1980, Enrichment of estradiol-receptor complexes in a transcriptionally active fraction of chromatin from MCF-7 cells, 77, 1291 Seitz, 1980, Iododestannylation. Position-specific synthesis of iodotamoxifen, J. Organomet. Chem., 186, C33, 10.1016/S0022-328X(00)89877-0 Senior, 1978, Evidence for two kinds of chromatin binding sties for the estradiol-receptor complex, Cell, 14, 857, 10.1016/0092-8674(78)90341-0 Shyamula, 1969, Estrogen receptors in the rat uterus: Studies on the interaction of cytosol and nuclear binding sites, J. Biol. Chem., 244, 1097, 10.1016/S0021-9258(18)91813-2 Stöcklin, 1979, Chemical and biological effects of (3-decay and inner-shell ionization in biomolecules: a new approach to radiation biology, 382 Turner, 1976, Fragmentation of chromatin with 125I radioactive disintegrations, Biophys. J., 16, 1003, 10.1016/S0006-3495(76)85751-7 Waring, 1970, Variation of the supercoils in closed circular DNA by binding of antibiotics and drugs: Evidence for molecular models involving intercalation, J. Mol. Biol., 54, 247, 10.1016/0022-2836(70)90429-8 Warters, 1977, Radionuclide toxicity in cultured mammalian cells: Elucidation of the primary site for radiation damage, Curr. Topics Radial. Res. Q., 12, 389 Wexler, 1967, Destruction of molecules by nuclear transformations, Science, 156, 901, 10.1126/science.156.3777.901 Williams, 1974, Equilibrium binding of estradiol by uterine cell suspensions and whole uteri in vitro, Biochemistry, 13, 5537, 10.1021/bi00724a013 Zava, 1977, Human breast cancer: Biologically active estrogen receptor in the absence of estrogen?, Science, 196, 663, 10.1126/science.193182