Long Noncoding RNA ADINR Regulates Adipogenesis by Transcriptionally Activating C/EBPα

Elsevier BV - Tập 5 - Trang 856-865 - 2015
Tengfei Xiao1,2,3, Lihui Liu1,2,4, Hongling Li5, Yu Sun1,2,4, Huaxia Luo1,2,4, Tangping Li5, Shihua Wang5, Stephen Dalton6, Robert Chunhua Zhao5, Runsheng Chen1,2
1Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
2Key Laboratory of Non-coding RNA, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
3Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Harvard School of Public Health, Boston, MA 02215, USA
4Graduate School of the Chinese Academy of Sciences, Beijing 100080, China
5Center of Excellence in Tissue Engineering, Institute of Basic Medical Sciences, School of Basic Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100005, China
6Paul D. Coverdell Center for Biomedical and Health Sciences, Department of Biochemistry and Molecular Biology, The University of Georgia, 500 D.W. Brooks Drive, Athens, GA 30602, USA

Tài liệu tham khảo

Bernstein, 2006, A bivalent chromatin structure marks key developmental genes in embryonic stem cells, Cell, 125, 315, 10.1016/j.cell.2006.02.041 Cabili, 2011, Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses, Genes Dev., 25, 1915, 10.1101/gad.17446611 Cao, 2005, Human adipose tissue-derived stem cells differentiate into endothelial cells in vitro and improve postnatal neovascularization in vivo, Biochem. Biophys. Res. Commun., 332, 370, 10.1016/j.bbrc.2005.04.135 Cheng, 2005, Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution, Science, 308, 1149, 10.1126/science.1108625 Cho, 2009, Histone methylation regulator PTIP is required for PPARgamma and C/EBPalpha expression and adipogenesis, Cell Metab., 10, 27, 10.1016/j.cmet.2009.05.010 Di Ruscio, 2013, DNMT1-interacting RNAs block gene-specific DNA methylation, Nature, 503, 371, 10.1038/nature12598 Farmer, 2006, Transcriptional control of adipocyte formation, Cell Metab., 4, 263, 10.1016/j.cmet.2006.07.001 Friedman, 2000, Obesity in the new millennium, Nature, 404, 632, 10.1038/35007504 Grote, 2013, The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse, Dev. Cell, 24, 206, 10.1016/j.devcel.2012.12.012 Guttman, 2012, Modular regulatory principles of large non-coding RNAs, Nature, 482, 339, 10.1038/nature10887 Guttman, 2009, Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals, Nature, 458, 223, 10.1038/nature07672 Guttman, 2011, lincRNAs act in the circuitry controlling pluripotency and differentiation, Nature, 477, 295, 10.1038/nature10398 Hsieh, 2014, Enhancer RNAs participate in androgen receptor-driven looping that selectively enhances gene activation, Proc. Natl. Acad. Sci. USA, 111, 7319, 10.1073/pnas.1324151111 Hung, 2011, Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters, Nat. Genet., 43, 621, 10.1038/ng.848 Janderová, 2003, Human mesenchymal stem cells as an in vitro model for human adipogenesis, Obes. Res., 11, 65, 10.1038/oby.2003.11 Janowski, 2005, Inhibiting gene expression at transcription start sites in chromosomal DNA with antigene RNAs, Nat. Chem. Biol., 1, 216, 10.1038/nchembio725 Kapranov, 2007, RNA maps reveal new RNA classes and a possible function for pervasive transcription, Science, 316, 1484, 10.1126/science.1138341 Kikuchi, 2009, Transcripts of unknown function in multiple-signaling pathways involved in human stem cell differentiation, Nucleic Acids Res., 37, 4987, 10.1093/nar/gkp426 Kim, 2010, Widespread transcription at neuronal activity-regulated enhancers, Nature, 465, 182, 10.1038/nature09033 Klattenhoff, 2013, Braveheart, a long noncoding RNA required for cardiovascular lineage commitment, Cell, 152, 570, 10.1016/j.cell.2013.01.003 Kretz, 2012, Suppression of progenitor differentiation requires the long noncoding RNA ANCR, Genes Dev., 26, 338, 10.1101/gad.182121.111 Lee, 2013, H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation, eLife, 2, e01503, 10.7554/eLife.01503 Loewer, 2010, Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells, Nat. Genet., 42, 1113, 10.1038/ng.710 Mohan, 2012, SnapShot: Histone lysine methylase complexes, Cell, 149, 498, 10.1016/j.cell.2012.03.025 Musahl, 2015, A long non-coding RNA links calreticulin-mediated immunogenic cell removal to RB1 transcription, Oncogene, 10.1038/onc.2014.424 Ørom, 2010, Long noncoding RNAs with enhancer-like function in human cells, Cell, 143, 46, 10.1016/j.cell.2010.09.001 Pandey, 2008, Kcnq1ot1 antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulation, Mol. Cell, 32, 232, 10.1016/j.molcel.2008.08.022 Pittenger, 1999, Multilineage potential of adult human mesenchymal stem cells, Science, 284, 143, 10.1126/science.284.5411.143 Ponjavic, 2007, Functionality or transcriptional noise? Evidence for selection within long noncoding RNAs, Genome Res., 17, 556, 10.1101/gr.6036807 Rinn, 2007, Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs, Cell, 129, 1311, 10.1016/j.cell.2007.05.022 Rosen, 2002, C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway, Genes Dev., 16, 22, 10.1101/gad.948702 Sigova, 2013, Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells, Proc. Natl. Acad. Sci. USA, 110, 2876, 10.1073/pnas.1221904110 Struhl, 2007, Transcriptional noise and the fidelity of initiation by RNA polymerase II, Nat. Struct. Mol. Biol., 14, 103, 10.1038/nsmb0207-103 Sun, 2013, Long noncoding RNAs regulate adipogenesis, Proc. Natl. Acad. Sci. USA, 110, 3387, 10.1073/pnas.1222643110 Tsai, 2010, Long noncoding RNA as modular scaffold of histone modification complexes, Science, 329, 689, 10.1126/science.1192002 Wang, 2011, A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression, Nature, 472, 120, 10.1038/nature09819 Wapinski, 2011, Long noncoding RNAs and human disease, Trends Cell Biol., 21, 354, 10.1016/j.tcb.2011.04.001 Zhao, 2008, Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome, Science, 322, 750, 10.1126/science.1163045