Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition

Journal of Clinical Investigation - Tập 126 Số 8 - Trang 3130-3144 - 2016
Leonid Cherkassky1,2, Aurore Morello1,2, Jonathan Villena‐Vargas1,2, Yang Feng3,4, Dimiter S. Dimitrov3,4, David R. Jones2, Michel Sadelain1, Prasad S. Adusumilli1,2
1Center for Cell Engineering and
2Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
3Laboratory of Experimental Immunology, Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, NIH, Frederick, Maryland, USA.
4Protein Interactions Section,

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