Age-related changes in total and regional fat distribution

Adiels, 2006, Overproduction of large VLDL particles is driven by increased liver fat content in man, Diabetologia, 49, 755, 10.1007/s00125-005-0125-z Akahoshi, 2001, Correlation between fatty liver and coronary risk factors: a population study of elderly men and women in Nagasaki, Japan, Hypertens. Res., 24, 337, 10.1291/hypres.24.337 Bachmann, 2001, Effects of intravenous and dietary lipid challenge on intramyocellular lipid content and the relation with insulin sensitivity in humans, Diabetes, 50, 2579, 10.2337/diabetes.50.11.2579 Banerji, 1995, Liver fat, serum triglycerides and visceral adipose tissue in insulin-sensitive and insulin-resistant black men with NIDDM, Int. J. Obes. Relat. Metab. Disord., 19, 846 Baumgartner, 1995, Cross-sectional age differences in body composition in persons 60+ years of age, J. Gerontol. A: Biol. Sci. Med. Sci., 50, M307, 10.1093/gerona/50A.6.M307 Bedogni, 2006, The Fatty Liver Index: a simple and accurate predictor of hepatic steatosis in the general population, BMC Gastroenterol., 6, 33, 10.1186/1471-230X-6-33 Bedogni, 2005, Prevalence of and risk factors for nonalcoholic fatty liver disease: the Dionysos nutrition and liver study, Hepatology, 42, 44, 10.1002/hep.20734 Bigaard, 2005, Waist circumference and body composition in relation to all-cause mortality in middle-aged men and women, Int. J. Obes. Relat. Metab. Disord., 29, 778, 10.1038/sj.ijo.0802976 Bjorntorp, 1990, “Portal” adipose tissue as a generator of risk factors for cardiovascular disease and diabetes, Arteriosclerosis, 10, 493, 10.1161/01.ATV.10.4.493 Boesch, 1999, Observation of intramyocellular lipids by means of 1H magnetic resonance spectroscopy, Proc. Nutr. Soc., 58, 841, 10.1017/S0029665199001147 Boesch, 2000, Observation of intramyocellular lipids by 1H-magnetic resonance spectroscopy, Ann. N Y Acad. Sci., 904, 25, 10.1111/j.1749-6632.2000.tb06417.x Borkan, 1985, Comparison of body composition in middle-aged and elderly males using computed tomography, Am. J. Phys. Anthropol., 66, 289, 10.1002/ajpa.1330660306 Borkan, 1983, Age changes in body composition revealed by computed tomography, J. Gerontol., 38, 673, 10.1093/geronj/38.6.673 Brown, 2003, Osteoporosis, Med. Clin. North Am., 87, 1039, 10.1016/S0025-7125(03)00065-8 Browning, 2004, Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity, Hepatology, 40, 1387, 10.1002/hep.20466 Calle, 1999, Body-mass index and mortality in a prospective cohort of U.S. adults, N. Engl. J. Med., 341, 1097, 10.1056/NEJM199910073411501 Carmelli, 1991, Longitudinal changes in fat distribution in the Western Collaborative Group Study: a 23-year follow-up, Int. J. Obes., 15, 67 Carroll, 2008, Visceral fat, waist circumference, and BMI: impact of race/ethnicity, Obesity, 16, 600, 10.1038/oby.2007.92 Chumlea, 2002, Body composition estimates from NHANES III bioelectrical impedance data, Int. J. Obes. Relat. Metab. Disord., 26, 1596, 10.1038/sj.ijo.0802167 Chung, 2005, Korean and Caucasian overweight premenopausal women have different relationship of body mass index to percent body fat with age, J. Appl. Physiol., 99, 103, 10.1152/japplphysiol.01153.2004 Cree, 2004, Intramuscular and liver triglycerides are increased in the elderly, J. Clin. Endocrinol. Metab., 89, 3864, 10.1210/jc.2003-031986 De Bisschop, 1993, Fat fraction of lumbar bone marrow using in vivo proton nuclear magnetic resonance spectroscopy, Bone, 14, 133, 10.1016/8756-3282(93)90239-7 DeFronzo, 1985, Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus, J. Clin. Invest., 76, 149, 10.1172/JCI111938 Despres, 2006, Abdominal obesity and metabolic syndrome, Nature, 444, 881, 10.1038/nature05488 Despres, 2000, Race, visceral adipose tissue, plasma lipids, and lipoprotein lipase activity in men and women: the Health, Risk Factors, Exercise Training, and Genetics (HERITAGE) family study, Arterioscler. Thromb. Vasc. Biol., 20, 1932, 10.1161/01.ATV.20.8.1932 Despres, 1989, Role of deep abdominal fat in the association between regional adipose tissue distribution and glucose tolerance in obese women, Diabetes, 38, 304, 10.2337/diabetes.38.3.304 Ding, 2007, Effects of birth cohort and age on body composition in a sample of community-based elderly, Am. J. Clin. Nutr., 85, 405, 10.1093/ajcn/85.2.405 Enzi, 1986, Subcutaneous and visceral fat distribution according to sex, age, and overweight, evaluated by computed tomography, Am. J. Clin. Nutr., 44, 739, 10.1093/ajcn/44.6.739 Falck-Ytter, 2001, Clinical features and natural history of nonalcoholic steatosis syndromes, Semin. Liver Dis., 21, 17, 10.1055/s-2001-12926 Fan, 2005, Fatty liver and the metabolic syndrome among Shanghai adults, J. Gastroenterol. Hepatol., 20, 1825, 10.1111/j.1440-1746.2005.04058.x Forouhi, 1999, Relation of triglyceride stores in skeletal muscle cells to central obesity and insulin sensitivity in European and South Asian men, Diabetologia, 42, 932, 10.1007/s001250051250 Franklin, 2009, Longitudinal changes in abdominal fat distribution with menopause, Metabolism, 58, 311, 10.1016/j.metabol.2008.09.030 Fuke, 2007, Increase of visceral fat area in Indonesians and Japanese with normal BMI, Diabet. Res. Clin. Pract., 77, S224, 10.1016/j.diabres.2007.01.062 Gallagher, 2000, Weight stability masks sarcopenia in elderly men and women, Am. J. Physiol. Endocrinol. Metab., 279, E366, 10.1152/ajpendo.2000.279.2.E366 Gallagher, 2000, Weight stability masks sarcopenia in elderly men and women, Am. J. Physiol. Endocrinol. Metab., 279, E366, 10.1152/ajpendo.2000.279.2.E366 Gallagher, 1996, How useful is body mass index for comparison of body fatness across age, sex, and ethnic groups?, Am. J. Epidemiol., 143, 228, 10.1093/oxfordjournals.aje.a008733 Gimble, 1996, The function of adipocytes in the bone marrow stroma: an update, Bone, 19, 421, 10.1016/S8756-3282(96)00258-X Goodpaster, 2001, Attenuation of skeletal muscle and strength in the elderly: The Health ABC Study, J. Appl. Physiol., 90, 2157, 10.1152/jappl.2001.90.6.2157 Goodpaster, 2000, Skeletal muscle attenuation determined by computed tomography is associated with skeletal muscle lipid content, J. Appl. Physiol., 89, 104, 10.1152/jappl.2000.89.1.104 Goodpaster, 2000, Composition of skeletal muscle evaluated with computed tomography, Ann. N Y Acad. Sci., 904, 18, 10.1111/j.1749-6632.2000.tb06416.x Goto, 1995, The influence of fatty liver on insulin clearance and insulin resistance in non-diabetic Japanese subjects, Int. J. Obes. Relat. Metab. Disord., 19, 841 Greco, 2002, Insulin resistance in morbid obesity: reversal with intramyocellular fat depletion, Diabetes, 51, 144, 10.2337/diabetes.51.1.144 Guo, 1999, Aging, body composition, and lifestyle: the Fels Longitudinal Study, Am. J. Clin. Nutr., 70, 405, 10.1093/ajcn/70.3.405 Hairston, 2009, Five-year change in visceral adipose tissue quantity in a minority cohort: The IRAS Family Study, Diabetes Care, 10.2337/dc09-0336 Haque, 2002, The metabolic abnormalities associated with non-alcoholic fatty liver disease, Best Pract. Res. Clin. Gastroenterol., 16, 709, 10.1053/bega.2002.0325 Hayashi, 2004, Visceral adiposity is an independent predictor of incident hypertension in Japanese Americans, Ann. Intern. Med., 140, 992, 10.7326/0003-4819-140-12-200406150-00008 Hoyert, 2006, Deaths: final data for 2003, Natl. Vital Stat. Rep., 54, 1 Huang, 2005, Obesity in the elderly and its relationship with cardiovascular risk factors in Taiwan, Obes. Res., 13, 170, 10.1038/oby.2005.22 Hughes, 2001, Longitudinal muscle strength changes in older adults: influence of muscle mass, physical activity, and health, J. Gerontol. A: Biol. Sci. Med. Sci., 56, B209, 10.1093/gerona/56.5.B209 Hughes, 2004, Anthropometric assessment of 10-y changes in body composition in the elderly, Am. J. Clin. Nutr., 80, 475, 10.1093/ajcn/80.2.475 Hunter, 1996, Intra-abdominal adipose tissue, physical activity and cardiovascular risk in pre- and post-menopausal women, Int. J. Obes. Relat. Metab. Disord., 20, 860 Hwang, 2001, Regional differences in intramyocellular lipids in humans observed by in vivo 1H-MR spectroscopic imaging, J. Appl. Physiol., 90, 1267, 10.1152/jappl.2001.90.4.1267 Iacobellis, 2003, Epicardial fat from echocardiography: a new method for visceral adipose tissue prediction, Obest. Res., 11, 304, 10.1038/oby.2003.45 Iacobellis, 2005, Epicardial adipose tissue and insulin resistance in obese subjects, J. Clin. Endocrinol. Metab., 90, 6300, 10.1210/jc.2005-1087 Iacobellis, 2003, Echocardiographic epicardial adipose tissue is related to anthropometric and clinical parameters of metabolic syndrome: a new indicator of cardiovascular risk, J. Clin. Endocrinol. Metab., 88, 5163, 10.1210/jc.2003-030698 Iacobellis, 2004, Relation between epicardial adipose tissue and left ventricular mass, Am. J. Cardiol., 94, 1084, 10.1016/j.amjcard.2004.06.075 Imada, 2007, Epidemiology of fat replacement of the right ventricular myocardium determined by multislice computed tomography using a logistic regression model, Int. J. Cardiol., 119, 410, 10.1016/j.ijcard.2006.07.174 Ito, 2001, Relation between body composition and age in healthy Japanese subjects, Eur. J. Clin. Nutr., 55, 462, 10.1038/sj.ejcn.1601206 Janssen, 2000, Skeletal muscle mass and distribution in 468 men and women aged 18–88 yr, J. Appl. Physiol., 89, 81, 10.1152/jappl.2000.89.1.81 Justesen, 2001, Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis, Biogerontology, 2, 165, 10.1023/A:1011513223894 Kadowaki, 2006, Japanese men have larger areas of visceral adipose tissue than Caucasian men in the same levels of waist circumference in a population-based study, Int. J. Obes. Relat. Metab. Disord., 30, 1163, 10.1038/sj.ijo.0803248 Kamel, 2000, Change in intra-abdominal adipose tissue volume during weight loss in obese men and women: correlation between magnetic resonance imaging and anthropometric measurements, Int. J. Obes. Relat. Metab. Disord., 24, 607, 10.1038/sj.ijo.0801204 Kanaya, 2003, Association of total and central obesity with mortality in postmenopausal women with coronary heart disease, Am. J. Epidemiol., 158, 1161, 10.1093/aje/kwg271 Kankaanpaa, 2006, Myocardial triglyceride content and epicardial fat mass in human obesity: relationship to left ventricular function and serum free fatty acid levels, J. Clin. Endocrinol. Metab., 91, 4689, 10.1210/jc.2006-0584 Katsiaras, 2005, Skeletal muscle fatigue, strength, and quality in the elderly: the Health ABC Study, J. Appl. Physiol., 99, 210, 10.1152/japplphysiol.01276.2004 Kelley, 1999, Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss, Am. J. Physiol., 277, E1130 Kelley, 2003, Fatty liver in type 2 diabetes mellitus: relation to regional adiposity, fatty acids, and insulin resistance, Am. J. Physiol. Endocrinol. Metab., 285, E906, 10.1152/ajpendo.00117.2003 Kohrt, 1995, Loss of skeletal muscle mass with aging: effect on glucose tolerance., J. Gerontol. A: Biol. Sci. Med. Sci., 50, 68 Kotani, 1994, Sexual dimorphism of age-related changes in whole-body fat distribution in the obese, Int. J. Obes. Relat. Metab. Disord., 18, 207 Krssak, 1999, Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study, Diabetologia, 42, 113, 10.1007/s001250051123 Krzywicki, 1967, Human body density and fat of an adult male population as measured by water displacement, Am. J. Clin. Nutr., 20, 305, 10.1093/ajcn/20.4.305 Kugel, 2001, Age-and sex-specific differences in the 1H-spectrum of vertebral bone marrow, J. Magn. Reson. Imaging, 13, 263, 10.1002/1522-2586(200102)13:2<263::AID-JMRI1038>3.0.CO;2-M Kuk, 2006, Visceral fat is an independent predictor of all-cause mortality in men, Obes. Res., 14, 336, 10.1038/oby.2006.43 Kuk, 2005, Waist circumference and abdominal adipose tissue distribution: influence of age and sex, Am. J. Clin. Nutr., 81, 1330, 10.1093/ajcn/81.6.1330 Kyle, 2001, Age-related differences in fat-free mass, skeletal muscle, body cell mass and fat mass between 18 and 94 years, Eur. J. Clin. Nutr., 55, 663, 10.1038/sj.ejcn.1601198 Kyle, 2001, Total body mass, fat mass, fat-free mass, and skeletal muscle in older people: cross-sectional differences in 60-year-old persons, J. Am. Geriatr. Soc., 49, 1633, 10.1111/j.1532-5415.2001.49272.x Lara-Castro, 2002, Visceral adipose tissue in women: longitudinal study of the effects of fat gain, time, and race, Obes. Res., 10, 868, 10.1038/oby.2002.119 Lei, 2006, Relationship of total body fatness and five anthropometric indices in Chinese aged 20–40 years: different effects of age and gender, Eur. J. Clin. Nutr., 60, 511, 10.1038/sj.ejcn.1602345 Lemieux, 2004, Energy partitioning in gluteal-femoral fat: does the metabolic fate of triglycerides affect coronary heart disease risk?, Arterioscler. Thromb. Vasc. Biol., 24, 795, 10.1161/01.ATV.0000126485.80373.33 Lewis, 2002, Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes, Endocr. Rev., 23, 201, 10.1210/er.23.2.201 Liney, 2007, Age, gender, and skeletal variation in bone marrow composition: a preliminary study at 3.0 Tesla, J. Magn. Reson. Imaging, 26, 787, 10.1002/jmri.21072 Luyckx, 2000, Non-alcoholic steatohepatitis: association with obesity and insulin resistance, and influence of weight loss, Diabetes Metab., 26, 98 Machann, 2005, Age and gender related effects on adipose tissue compartments of subjects with increased risk for type 2 diabetes: a whole body MRI/MRS study, Magma, 18, 128, 10.1007/s10334-005-0104-x Machann, 2005, Age and gender related effects on adipose tissue compartments of subjects with increased risk for type 2 diabetes: a whole body MRI/MRS study, Magma, 18, 128, 10.1007/s10334-005-0104-x Mahmood, 1998, Association of fatty liver with increased ratio of visceral to subcutaneous adipose tissue in obese men, Acta Med. Okayama, 52, 225 Marchesini, 1999, Association of nonalcoholic fatty liver disease with insulin resistance, Am. J. Med., 107, 450, 10.1016/S0002-9343(99)00271-5 Mazurek, 2003, Human epicardial adipose tissue is a source of inflammatory mediators, Circulation, 108, 2460, 10.1161/01.CIR.0000099542.57313.C5 Meunier, 1971, Osteoporosis and the replacement of cell populations of the marrow by adipose tissue. A quantitative study of 84 iliac bone biopsies, Clin. Orthop. Relat. Res., 80, 147, 10.1097/00003086-197110000-00021 Mitsiopoulos, 1998, Cadaver validation of skeletal muscle measurement by magnetic resonance imaging and computerized tomography, J. Appl. Physiol., 85, 115, 10.1152/jappl.1998.85.1.115 Montani, 2004, Ectopic fat storage in heart, blood vessels and kidneys in the pathogenesis of cardiovascular diseases, Int. J. Obes. Relat. Metab. Disord., 28, S58, 10.1038/sj.ijo.0802858 Newman, 2003, Strength and muscle quality in a well-functioning cohort of older adults: the Health. Aging and Body Composition Study, J. Am. Geriatr. Soc., 51, 323, 10.1046/j.1532-5415.2003.51105.x Nguyen-Duy, 2003, Visceral fat and liver fat are independent predictors of metabolic risk factors in men, Am. J. Physiol. Endocrinol. Metab., 284, E1065, 10.1152/ajpendo.00442.2002 Noppa, 1980, Longitudinal studies of anthropometric data and body composition. The population study of women in Gotenberg, Sweden, Am. J. Clin. Nutr., 33, 155, 10.1093/ajcn/33.1.155 Pan, 1997, Skeletal muscle triglyceride levels are inversely related to insulin action, Diabetes, 46, 983, 10.2337/diabetes.46.6.983 Park, 2001, Larger amounts of visceral adipose tissue in Asian Americans, Obes. Res., 9, 381, 10.1038/oby.2001.49 Perseghin, 1999, Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents, Diabetes, 48, 1600, 10.2337/diabetes.48.8.1600 Phillips, 1996, Intramuscular triglyceride and muscle insulin sensitivity: evidence for a relationship in nondiabetic subjects, Metabolism, 45, 947, 10.1016/S0026-0495(96)90260-7 Rabkin, 2007, Epicardial fat: properties, function and relationship to obesity, Obes. Rev., 8, 253, 10.1111/j.1467-789X.2006.00293.x Raguso, 2006, A 3-year longitudinal study on body composition changes in the elderly: role of physical exercise, Clin. Nutr., 25, 573, 10.1016/j.clnu.2005.10.013 Reingold, 2005, Determination of triglyceride in the human myocardium by magnetic resonance spectroscopy: reproducibility and sensitivity of the method, Am. J. Physiol. Endocrinol. Metab., 289, E935, 10.1152/ajpendo.00095.2005 Rosen, 2006, Mechanisms of disease: is osteoporosis the obesity of bone?, Nat. Clin. Pract. Rheumatol., 2, 35, 10.1038/ncprheum0070 Ross, 1996, Sensitivity associated with the identification of visceral adipose tissue levels using waist circumference in men and women: effects of weight loss, Int. J. Obes. Relat. Metab. Disord., 20, 533 Ryan, 1999, Age-related changes in fat deposition in mid-thigh muscle in women: relationships with metabolic cardiovascular disease risk factors, Int. J. Obes. Relat. Metab. Disord., 23, 126, 10.1038/sj.ijo.0800777 Rzonca, 2004, Bone is a target for the antidiabetic compound rosiglitazone, Endocrinology, 145, 401, 10.1210/en.2003-0746 Schick, 2002, MRI of muscular fat, Magn. Reson. Med., 47, 720, 10.1002/mrm.10107 Schwartz, 2006, Thiazolidinedione use and bone loss in older diabetic adults, J. Clin. Endocrinol. Metab., 91, 3349, 10.1210/jc.2005-2226 Seppala-Lindroos, 2002, Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men, J. Clin. Endocrinol. Metab., 87, 3023, 10.1210/jc.87.7.3023 Sharma, 2004, Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart, FASEB J., 18, 1692, 10.1096/fj.04-2263com Shen, 2003, Adipose tissue quantification by imaging methods: a proposed classification, Obes. Res., 11, 5, 10.1038/oby.2003.3 Shimokata, 1989, Studies in the distribution of body fat. II. Longitudinal effects of change in weight, Int. J. Obes., 13, 455 Shimokata, 1989, Studies in the distribution of body fat: I. Effects of age, sex, and obesity, J. Gerontol., 44, M66, 10.1093/geronj/44.2.M66 Silaghi, 2008, Epicardial adipose tissue extent: relationship with age, body fat distribution, and coronaropathy, Obesity, 16, 2424, 10.1038/oby.2008.379 Sites, 2001, Relationship between hormone replacement therapy use with body fat distribution and insulin sensitivity in obese postmenopausal women, Metabolism, 50, 835, 10.1053/meta.2001.24878 Slawik, 2006, Lipotoxicity, overnutrition and energy metabolism in aging, Ageing Res. Rev., 5, 144, 10.1016/j.arr.2006.03.004 Stanforth, 2004, Generalized abdominal visceral fat prediction models for black and white adults aged 17-65 y: the HERITAGE Family Study, Int. J. Obes. Relat. Metab. Disord., 28, 925, 10.1038/sj.ijo.0802563 Stevens, 1998, The effect of age on the association between body-mass index and mortality, N. Engl. J. Med., 338, 1, 10.1056/NEJM199801013380101 Sumino, 2003, Effects of hormone replacement therapy on weight, abdominal fat distribution, and lipid levels in Japanese postmenopausal women, Int. J. Obes. Relat. Metab. Disord., 27, 1044, 10.1038/sj.ijo.0802371 Szczepaniak, 1999, Measurement of intracellular triglyceride stores by H spectroscopy: validation in vivo, Am. J. Physiol., 276, E977 Szczepaniak, 2003, Myocardial triglycerides and systolic function in humans: in vivo evaluation by localized proton spectroscopy and cardiac imaging, Magn. Reson. Med., 49, 417, 10.1002/mrm.10372 Taguchi, 2001, Pericardial fat accumulation in men as a risk factor for coronary artery disease, Atherosclerosis, 157, 203, 10.1016/S0021-9150(00)00709-7 Tchernof, 2004, Ovarian hormone status and abdominal visceral adipose tissue metabolism, J. Clin. Endocrinol. Metab., 89, 3425, 10.1210/jc.2003-031561 Teh, 1996, The reallocation of body fat toward the abdomen persists to very old age, while body mass index declines after middle age in Chinese, Int. J. Obes. Relat. Metab. Disord., 20, 683 Tiikkainen, 2002, Liver-fat accumulation and insulin resistance in obese women with previous gestational diabetes, Obes. Res., 10, 859, 10.1038/oby.2002.118 Toth, 2000, Effect of menopausal status on body composition and abdominal fat distribution, Int. J. Obes. Relat. Metab. Disord., 24, 226, 10.1038/sj.ijo.0801118 Tsunenari, 1993, Age- and gender-related changes in body composition in Japanese subjects, J. Bone Miner. Res., 8, 397, 10.1002/jbmr.5650080403 Unger, 2005, Longevity, lipotoxicity and leptin: the adipocyte defense against feasting and famine, Biochimie, 87, 57, 10.1016/j.biochi.2004.11.014 Uranga, 2005, Isotope tracer measures of meal fatty acid metabolism: reproducibility and effects of the menstrual cycle, Am. J. Physiol. Endocrinol. Metab., 288, E547, 10.1152/ajpendo.00340.2004 van der Kooy, 1993, Waist-hip ratio is a poor predictor of changes in visceral fat, Am. J. Clin. Nutr., 57, 327, 10.1093/ajcn/57.3.327 Visscher, 2001, A comparison of body mass index, waist-hip ratio and waist circumference as predictors of all-cause mortality among the elderly: the Rotterdam study, Int. J. Obes. Relat. Metab. Disord., 25, 1730, 10.1038/sj.ijo.0801787 Visser, 2005, Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older persons, J. Gerontol. A: Biol. Sci. Med. Sci., 60, 324, 10.1093/gerona/60.3.324 Visser, 2002, Leg muscle mass and composition in relation to lower extremity performance in men and women aged 70 to 79: the health, aging and body composition study, J. Am. Geriatr. Soc., 50, 897, 10.1046/j.1532-5415.2002.50217.x Visser, 2003, One- and two-year change in body composition as measured by DXA in a population-based cohort of older men and women, J. Appl. Physiol., 94, 2368, 10.1152/japplphysiol.00124.2002 Wehrli, 2000, Cross-sectional study of osteopenia with quantitative MR imaging and bone densitometry, Radiology, 217, 527, 10.1148/radiology.217.2.r00nv20527 Wendling, 1996, Variability of triacylglycerol content in human skeletal muscle biopsy samples, J. Appl. Physiol., 81, 1150, 10.1152/jappl.1996.81.3.1150 Westerbacka, 2004, Women and men have similar amounts of liver and intra-abdominal fat, despite more subcutaneous fat in women: implications for sex differences in markers of cardiovascular risk, Diabetologia, 47, 1360, 10.1007/s00125-004-1460-1 Weston, 2005, Racial and ethnic distribution of nonalcoholic fatty liver in persons with newly diagnosed chronic liver disease, Hepatology, 41, 372, 10.1002/hep.20554 Yeung, 2005, Osteoporosis is associated with increased marrow fat content and decreased marrow fat unsaturation: a proton MR spectroscopy study, J. Magn. Reson. Imaging, 22, 279, 10.1002/jmri.20367 Zamboni, 1997, Effects of age on body fat distribution and cardiovascular risk factors in women, Am. J. Clin. Nutr., 66, 111, 10.1093/ajcn/66.1.111 Zamboni, 2003, Body composition changes in stable-weight elderly subjects: the effect of sex, Aging Clin. Exp. Res., 15, 321, 10.1007/BF03324517