Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab

Annals of Oncology - Tập 28 - Trang 1368-1379 - 2017
N. Chaput1,2, P. Lepage3, C. Coutzac1,4, E. Soularue1,4,5, K. Le Roux3, C. Monot3, L. Boselli1, E. Routier6, L. Cassard1, M. Collins4,5, T. Vaysse4,5, L. Marthey4,5, A. Eggermont6,7, V. Asvatourian8,9, E. Lanoy8,9, C. Mateus4, C. Robert4,6, F. Carbonnel4,5
1Laboratory of Immunomonitoring in Oncology, CNRS-UMS 3655 and INSERM-US23, Gustave Roussy Cancer Campus, Villejuif
2Faculty of Pharmacy, Chatenay-Malabry
3Micalis Institute, INRA, AgroParisTech, Paris
4Faculty of Medicine, University Paris-Saclay, Le Kremlin Bicêtre
5Department of Gastroenterology, Kremlin Bicêtre Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Le Kremlin Bicêtre
6Dermatology Unit, Department of Medicine, Gustave Roussy, Cancer Campus, Villejuif
7INSERM U1015, Gustave Roussy, Cancer Campus, Villejuif
8Biostatistics and Epidemiology Unit, Gustave Roussy Cancer Campus (GRCC), Villejuif
9University Paris-Saclay, Université Paris-Sud, UVSQ, CESP, INSERM, Villejuif, France

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