Mesenchymal stem cells: building blocks for molecular medicine in the 21st century

Trends in Molecular Medicine - Tập 7 - Trang 259-264 - 2001
Arnold I Caplan1, Scott P Bruder2
1Dept of Biology, Skeletal Research Center, Case Western Reserve University, Cleveland, OH, USA
2DePuy Orthopaedics, Inc., 325 Paramount Drive, Raynham, MA 02767, and Dept of Orthopaedics, Skeletal Research Center, Case Western Reserve University, Cleveland, OH, USA

Tài liệu tham khảo

Pedersen, 1999, Embryonic stem cells for medicine, Sci. Am., 280, 68, 10.1038/scientificamerican0499-68 Till, 1980, Hematopoietic stem cells, 5 Caplan, 1991, Mesenchymal stem cells, J. Orthop. Res., 9, 641, 10.1002/jor.1100090504 Pittenger, 1999, Multilineage potential of adult human mesenchymal stem cells, Science, 284, 143, 10.1126/science.284.5411.143 Champagne, 1994, CD34+ progenitor/stem cells for transplantation, Hematol. Rev., 8, 15 Caplan, 1994, The mesengenic process, Clin. Plastic Surg., 21, 429, 10.1016/S0094-1298(20)31020-8 Haynesworth, 1992, Cell surface antigens on human marrow-derived mesenchymal cells are detected by monoclonal antibodies, Bone, 13, 69, 10.1016/8756-3282(92)90363-2 Bruder, 1998, Mesenchymal stem cell surface antigen SB-10 corresponds to activated leukocyte cell adhesion molecule and is involved in osteogenic differentiation, J. Bone Miner. Res., 13, 655, 10.1359/jbmr.1998.13.4.655 Barry, 1999, The monoclonal antibody SH-2, raised against human mesenchymal stem cells, recognizes an epitope on endoglin (CD105), Biochem. Biophys. Res. Commun., 264, 134, 10.1006/bbrc.1999.1620 Deans, 2000, Mesenchymal stem cells: biology and potential clinical uses, Exp. Hematol., 28, 875, 10.1016/S0301-472X(00)00482-3 Bergman, 1996, Age-related changes in osteogenic stem cell in mice, J. Bone Miner. Res., 11, 568, 10.1002/jbmr.5650110504 Inoue, 1997, The effect of aging on bone formation in porous hydroxyapatite: biochemical and histological analysis, J. Bone Miner. Res., 12, 989, 10.1359/jbmr.1997.12.6.989 Kahn, 1995, Age-related bone loss: a hypothesis and initial assessment in mice, Clin. Orthop. Rel. Res., 313, 69 Quarto, 1995, Bone progenitor cell deficits and the age-associated decline in bone repair capacity, Calcif. Tissue Int., 56, 123, 10.1007/BF00296343 Tabuchi, 1986, Bone deficit in ovariectomized rats, J. Clin. Invest., 78, 637, 10.1172/JCI112621 Tsuji, 1990, Effect of donor age on osteogenic cells of rat bone marrow in vitro, Mech. Ageing Dev., 51, 121, 10.1016/0047-6374(90)90094-V Wei, 2000, Stem cell plasticity in mammals and transdetermination in Drosophila: common themes?, Stem Cells, 18, 409, 10.1634/stemcells.18-6-409 Lagasse, 2000, Purified hematopoietic stem cells can differentiate into hepatocytes in vivo, Nat. Med., 6, 1229, 10.1038/81326 Jackson, 1999, Hematopoietic potential of stem cells isolated from murine skeletal muscle, Proc. Natl. Acad. Sci. U. S. A., 96, 14482, 10.1073/pnas.96.25.14482 Azizi, 1998, Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats – similarities to astrocyte grafts, Proc. Natl. Acad. Sci. U. S. A., 95, 3908, 10.1073/pnas.95.7.3908 Kahn, 1977, Chondrocyte-to-osteocyte transformation in grafts of perichondrium-free epiphyseal cartilage, Clin. Orthop. Rel. Res., 129, 299, 10.1097/00003086-197711000-00042 Bennett, 1991, Adipocytic cells cultured from marrow have osteogenic potential, J. Cell Sci., 99, 131, 10.1242/jcs.99.1.131 Weissman, 2000, Translating stem and progenitor cell biology to the clinic: barriers and opportunities, Science, 287, 1442, 10.1126/science.287.5457.1442 Bianco, 1999, Multipotential cells in the bone marrow stroma: regulation in the context of organ physiology, Crit. Rev. Eukaryot. Gene Expr., 9, 159, 10.1615/CritRevEukarGeneExpr.v9.i2.30 Haynesworth, 1992, Characterization of cells with osteogenic potential from human marrow, Bone, 13, 81, 10.1016/8756-3282(92)90364-3 Bruder, 1997, Growth kinetics, self-renewal and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation, J. Cell Biochem., 64, 278, 10.1002/(SICI)1097-4644(199702)64:2<278::AID-JCB11>3.0.CO;2-F Jaiswal, 1997, Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro, J. Cell Biochem., 64, 295, 10.1002/(SICI)1097-4644(199702)64:2<295::AID-JCB12>3.0.CO;2-I Johnstone, 1998, In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells, Exp. Cell Res., 238, 265, 10.1006/excr.1997.3858 Wakitani, 1995, Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5-azacytidine, Muscle Nerve, 18, 1417, 10.1002/mus.880181212 Haynesworth, 1996, Cytokine expression by human marrow-derived mesenchymal progenitor cells in vitro: Effects of dexamethasone and IL-1a, J. Cell Physiol., 166, 585, 10.1002/(SICI)1097-4652(199603)166:3<585::AID-JCP13>3.0.CO;2-6 Jaiswal, 1997, Human osteoblastic cells secrete paracrine factors which regulate differentiation of osteogenic precursors in marrow, Trans. Orthop. Res. Soc., 22, 524 Dennis, 1996, Differentiation potential of conditionally immortalized mesenchymal progenitor cells from adult marrow of a H-2Kb–tsA58 transgenic mouse, J. Cell Physiol., 167, 523, 10.1002/(SICI)1097-4652(199606)167:3<523::AID-JCP16>3.0.CO;2-4 Dennis, 1999, A quadripotential mesenchymal progenitor cell isolated from the marrow of an adult mouse, J. Bone Miner. Res., 14, 1, 10.1359/jbmr.1999.14.5.700 Jaiswal, 2000, Differentiation of human mesenchymal stem cells by transforming growth factor β superfamily: expression of osteoblast phenotype by BMP-2 and BMP-4, J. Bone Miner. Res., 14, 240 Ducy, 1997, Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation, Cell, 89, 747, 10.1016/S0092-8674(00)80257-3 Bruder, 1998, Mesenchymal stem cells in osteobiology and applied bone regeneration, Clin. Orthop. Rel. Res., 355, 247, 10.1097/00003086-199810001-00025 Wakitani, 1994, Mesenchymal cell-based repair of large full-thickness defects of articular cartilage, J. Bone Jt Surg., 76, 579, 10.2106/00004623-199404000-00013 Young, 1998, The use of mesenchymal stem cells in a collagen matrix for achilles tendon repair, J. Orthop. Res., 16, 406, 10.1002/jor.1100160403 Mosca, 2000, Mesenchymal stem cells as vehicles for gene therapy, Clin. Orthop. Rel. Res., 379-S, 71, 10.1097/00003086-200010001-00011 Saito, 1995, Myogenic expression of mesenchymal stem cells within myotubes of mdx mice in vitro and in vivo, Tissue Eng., 1, 327, 10.1089/ten.1995.1.327 Balk, 1997, Effect of rhBMP-2 on the osteogenic potential of bone marrow stromal cells from an osteogenesis imperfecta mouse (oim), Bone, 21, 7, 10.1016/S8756-3282(97)00075-6 Caplan, 1995, Osteogenesis imperfecta, rehabilitation medicine and fundamental research, Conn. Tissue Res., 31, S9, 10.3109/03008209509116826 Horwitz, 1999, Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta, Nat. Med., 5, 309, 10.1038/6529 Pereira, 1998, Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta, Proc. Natl. Acad. Sci. U.S. A., 95, 1142, 10.1073/pnas.95.3.1142 Allay, 1997, LacZ and IL-3 expression in vivo after retroviral transduction of marrow-derived human osteogenic mesenchymal progenitors, Hum. Gene Ther., 8, 1417, 10.1089/hum.1997.8.12-1417 Lieberman, 1998, Regional gene therapy with a BMP-2-producing murine stromal cell line induces heterotopic and orthotopic bone formation in rodents, J. Orthop. Res., 16, 330, 10.1002/jor.1100160309 Gross, 1997, Fresh osteochondral allografts for post-traumatic knee defects: surgical technique, Oper. Tech. Orthop., 7, 334, 10.1016/S1048-6666(97)80037-7 Livingston, 2001, Repair of canine segmental bone defects using allogeneic mesenchymal stem cells, Trans. Ortho. Res. Soc., 26, 49 Lazarus, 1995, Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic use, Bone Marrow Transplant, 16, 557 Koc, 2000, Rapid hematopoietic recovery after co-infusion of autologous blood stem cells and culture expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high dose chemotherapy, J. Clin. Oncol., 18, 307, 10.1200/JCO.2000.18.2.307 Gao, J. et al. The dymanic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion. Cells Tissues Organs (in press) Murphy, 2001, Injected mesenchymal stem cells stimulate meniscal repair and protection of articular cartilage, Trans. Orthop. Res. Soc., 26, 193 Shafritz, 1998, Differential expression of bone and cartilage related genes in fibrodysplasia ossificans progressiva, myositis ossificans traumatica, and osteogenic sarcoma, Clin. Orthop. Rel. Res., 346, 46, 10.1097/00003086-199801000-00008 Bruder, S.P. Bone generation and regeneration: from embryonic chicks to human clinical therapy. Clin. Orthop. Rel. Res. (in press) Caplan, 1994, Endochondral bone formation: The lineage cascade, 8, 1 Cancedda, 2000, Developmental control of chondrogenesis and osteogenesis, Int. J. Dev. Biol., 44, 707 Olsen, 2000, Bone development, Annu. Rev. Cell Dev. Biol., 16, 191, 10.1146/annurev.cellbio.16.1.191 Ducy, 2000, The osteoblast: a sophisticated fibroblast under central surveillance, Science, 289, 1501, 10.1126/science.289.5484.1501 de Crombrugghe, 2000, Transcriptional mechanisms of chondrocyte differentiation, Matrix Biol., 19, 389, 10.1016/S0945-053X(00)00094-9 Brand-Saberi, 1999, Genetic and epigenetic control of muscle development in vertebrates, Cell Tissue Res., 296, 199, 10.1007/s004410051281 Rosen, 2000, Molecular regulation of adipogenesis, Annu. Rev. Cell Dev. Biol., 16, 145, 10.1146/annurev.cellbio.16.1.145