Phage conversion of Shigella flexneri group antigens

Infection and Immunity - Tập 11 Số 4 - Trang 685-691 - 1975
P. Gemski, D. E. Koeltzow, Samuel B. Formal

Tóm tắt

A temperate phage, designated Sf6, has been isolated from Shigella flexneri 3a. Characterization of Sf6 revealed that it possesses the capacity for converting the S. flexneri 3,4 group antigen complex to group factor 6. Serological studies and chemical analysis of lipopolysaccharide from converted strains suggest that group factor 6 is a reflection of an acetylation of the preexisting 3,4 antigen complex. Evidence is provided that the 3,4 group antigen complex functions, at least in part, as a cell surface receptor site for Sf6 adsorption.

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