High risk (B3) breast lesions: What is the incidence of malignancy for individual lesion subtypes? A systematic review and meta-analysis

Cancer Research UK http://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/breast-cancer. Office for National Statistics, 2018 Ellis, 2001 Houssami, 2007, Borderline breast core needle histology: predictive values for malignancy in lesions of uncertain malignant potential (B3), Br J Canc, 96, 1253, 10.1038/sj.bjc.6603714 El-Sayed, 2008, Predictive value of needle core biopsy diagnoses of lesions of uncertain malignant potential (B3) in abnormalities detected by mammographic screening, Histopathology, 53, 650, 10.1111/j.1365-2559.2008.03158.x Lieske, 2008, Screen-detected breast lesions with an indeterminate (B3) core needle biopsy should be excised, Eur J Surg Oncol: J Europ Soc Surg Oncol British Assoc Surg Oncol, 34, 1293, 10.1016/j.ejso.2007.11.005 Andreu, 2007, Breast core biopsy reporting categories--An internal validation in a series of 3054 consecutive lesions, Breast, 16, 94, 10.1016/j.breast.2006.06.009 Deb, 2015 Bianchi, 2011, Positive predictive value for malignancy on surgical excision of breast lesions of uncertain malignant potential (B3) diagnosed by stereotactic vacuum-assisted needle core biopsy (VANCB): a large multi-institutional study in Italy, Breast, 20, 264, 10.1016/j.breast.2010.12.003 National Institute for Health and Care Excellence, 2006 Brem, 2005, Percutaneous biopsy of papillary lesions of the breast: accuracy of pathologic diagnosis, J Wom Imag, 7, 157 Carder, 2005, Needle core biopsy can reliably distinguish between benign and malignant papillary lesions of the breast, Histopathology, 46, 320, 10.1111/j.1365-2559.2005.02082.x Carder, 2008, Large volume ‘mammotome’ biopsy may reduce the need for diagnostic surgery in papillary lesions of the breast, J Clin Pathol, 61, 928, 10.1136/jcp.2008.057158 Borrelli Stroup, 2000, Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis of Observational Studies in Epidemiology (MOOSE) group, J Am Med Assoc, 283, 2008, 10.1001/jama.283.15.2008 Burbank, 1997, Stereotactic breast biopsy of atypical ductal hyperplasia and ductal carcinoma in situ lesions: improved accuracy with directional, vacuum-assisted biopsy, Radiology, 202, 843, 10.1148/radiology.202.3.9051043 Maxwell, 2013, Benign papilloma diagnosed on image-guided 14 G core biopsy of the breast: effect of lesion type on likelihood of malignancy at excision, Clin Radiol, 68, 383, 10.1016/j.crad.2012.06.136 Tennant, 2008, Vacuum-assisted excision of breast lesions of uncertain malignant potential (B3) - an alternative to surgery in selected cases, Breast, 17, 546, 10.1016/j.breast.2008.08.005 Youk, 2012, US-guided vacuum-assisted percutaneous excision for management of benign papilloma without atypia diagnosed at US-guided 14-gauge core needle biopsy, Ann Surg Oncol, 19, 922, 10.1245/s10434-011-2033-4 Wells Higgins, 2002, Quantifying heterogeneity in a meta-analysis, Stat Med, 21, 1539, 10.1002/sim.1186 Higgins, 2003, Measuring inconsistency in meta-analyses, BMJ (Clin Res ed.), 327, 557, 10.1136/bmj.327.7414.557 Nyaga, 2014, Metaprop: a Stata command to perform meta-analysis of binomial data, Arch Public Health, 72, 39, 10.1186/2049-3258-72-39 de Beça, 2013, Improved malignancy prediction by B3 breast lesions subclassification, Ann Diagn Pathol, 17, 434, 10.1016/j.anndiagpath.2013.05.003 Yu, 2010, Diagnostic value of vacuum-assisted breast biopsy for breast carcinoma: a meta-analysis and systematic review, Breast Canc Res Treat, 120, 469, 10.1007/s10549-010-0750-1 Rageth, 2016, First International Consensus Conference on lesions of uncertain malignant potential in the breast (B3 lesions), Breast Canc Res Treat, 159, 203, 10.1007/s10549-016-3935-4 Lourenco, 2014, High-risk lesions at MRI-guided breast biopsy: frequency and rate of underestimation, Am J Roentgenol, 203, 682, 10.2214/AJR.13.11905 Oliveira, 2014, Evolving concepts in breast lobular neoplasia and invasive lobular carcinoma, and their impact on imaging methods, Insights into Imag, 5, 183, 10.1007/s13244-014-0324-6 Hwang, 2008, Atypical lobular hyperplasia and classic lobular carcinoma in situ in core biopsy specimens: routine excision is not necessary, Mod Pathol: Off J United States Canad Acad Pathol Inc, 21, 1208, 10.1038/modpathol.2008.134 Cangiarella, 2008, Is surgical excision necessary for the management of atypical lobular hyperplasia and lobular carcinoma in situ diagnosed on core needle biopsy?: a report of 38 cases and review of the literature, Arch Pathol Lab Med, 132, 979, 10.5858/2008-132-979-ISENFT Houssami, 2014, Accuracy of screening mammography in women with a history of lobular carcinoma in situ or atypical hyperplasia of the breast, Breast Canc Res Treat, 145, 765, 10.1007/s10549-014-2965-z Rajan, 2012, New patient pathway using vacuum-assisted biopsy reduces diagnostic surgery for B3 lesions, Clin Radiol, 67, 244, 10.1016/j.crad.2011.09.002 Rakha, 2011, Characterization and outcome of breast needle core biopsy diagnoses of lesions of uncertain malignant potential (B3) in abnormalities detected by mammographic screening. International journal of cancer, J Int Cancer, 129, 1417 MacLean, 2013, Is mode of presentation of B3 breast core biopsies (Screen-Detected or symptomatic) a distinguishing factor in the final histopathologic result or risk of diagnosis of malignancy?, World J Surg, 37, 2607, 10.1007/s00268-013-2191-6 Jackman, 2012, False-negative diagnoses at stereotactic vacuum-assisted needle breast biopsy: long-term follow-up of 1,280 lesions and review of the literature, Am J Roentgenol, 192, 341, 10.2214/AJR.08.1127 Wen, 2013, Nonmalignant breast papillary lesions at core-needle biopsy: a meta-analysis of underestimation and influencing factors, Ann Surg Oncol, 20, 94, 10.1245/s10434-012-2590-1 Elmore, 2016, Variability in pathologists' interpretations of individual breast biopsy slides: a population perspective variability in interpretations of individual breast biopsy slides, Ann Intern Med, 164, 649, 10.7326/M15-0964