Pharmacological studies on novel muscarinic agonists, 1-oxa-8-azaspiro[4.5]decane derivatives, YM796 and YM954
Tài liệu tham khảo
Araujo, 1988, Differential alteration of various cholinergic markers in cortical and subcortical regions of human brain in Alzheimer's disease, J. Neurochem., 50, 1914, 10.1111/j.1471-4159.1988.tb02497.x
Birdsall, 1978, The binding of agonists to brain muscarinic receptors, Mol. Pharmacol., 14, 723
Bowen, 1976, Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies, Brain, 99, 459, 10.1093/brain/99.3.459
Brown, 1980, Antagonist discrimination between ganglionic and ileal muscarinic receptors, Br. J. Pharmacol., 71, 362, 10.1111/j.1476-5381.1980.tb10948.x
Caulfield, 1983, Central administration of the muscarinic receptor subtype-selective antagonist pirenzepine selectively impairs passive avoidance learning in the mouse, J. Pharm. Pharmacol., 35, 131, 10.1111/j.2042-7158.1983.tb04290.x
Costa, 1986, Carbacholand norepinephrine-stimulated phosphoinositide metabolism in rat brain: effect of chronic cholinesterase inhibition, J. Pharmacol. Exp. Ther., 239, 32
Court, 1986, Raising the ambient potassium ion concentration enhances carbachol stimulated phosphoinositide hydrolysis in rat brain hippocampal and cerebral cortical miniprisms, Naunyn-Schmiedeb. Arch. Pharmacol., 334, 10, 10.1007/BF00498734
Fisher, 1987, AF102B: a new M1 agonist with potential application in Alzheimer's disease, Soc. Neurosci. Abstr., 13, 657
Fisher, 1986, AF102B: a novel putative M1 agonist reverses AF64A-induced cognitive impairments in rats, Soc. Neurosci. Abstr., 12, 702
Fonnum, 1975, A rapid radiochemical method for the determination of choline acetyltransferase, J. Neurochem., 24, 407, 10.1111/j.1471-4159.1975.tb11895.x
Freedman, 1988, Biochemical measurement of muscarinic receptor efficacy and its role in receptor regulation, Trends Pharmacol. Sci. (Suppl.), 3, 54
Giraldo, 1987, Distribution of muscarinic receptor subtypes in rat brain as determined in binding studies with AF-DX 116 and pirenzepine, Life Sci., 40, 833, 10.1016/0024-3205(87)90031-2
Harada, 1989, Muscarinic receptor subtypes linked to phosphoinositide hydrolysis and acetylcholine release in rat brain, J. Neurochem., 52, S36A
Hepler, 1985, Lesions in nucleus basalis magnocellularis and medial septal area of rats produce qualitatively similar memory impairments, J. Neurosci., 5, 866, 10.1523/JNEUROSCI.05-04-00866.1985
Hollander, 1987, RS 86 in the treatment of Alzheimer's disease: cognitive and biological effects, Biol. Psychiat., 22, 1067, 10.1016/0006-3223(87)90049-7
Hulme, 1978, The binding of antagonists to brain muscarinic receptors, Mol. Pharmacol., 14, 737
Mash, 1985, Loss of M2 muscarinic receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation, Science, 228, 1115, 10.1126/science.3992249
Mochida, 1988, Dual synaptic effects of activating M1-muscarinic receptors, in superior cervical ganglia of rabbits, Brain Res., 455, 9, 10.1016/0006-8993(88)90107-2
Palacios, 1986, The pharmacological assessment of RS 86 (2-ethyl-8-methyl-2,8-diazaspiro-[4,5]-decan-1,3-dion hydrobromide); a potent specific muscarinic acetylcholine receptor agonist, European J. Pharmacol., 125, 45, 10.1016/0014-2999(86)90082-8
Perry, 1977, A cholinergic connection between normal aging and senile dementia in the human hippocampus, Neurosci. Lett., 6, 85, 10.1016/0304-3940(77)90070-2
Perry, 1978, Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia, Br. Med. J., 2, 1457, 10.1136/bmj.2.6150.1457
Reisine, 1978, Pre- and postsynaptic neurochemical alterations in Alzheimer's disease, Brain Res., 159, 477, 10.1016/0006-8993(78)90562-0
Salamone, 1986, Behavioral functions of nucleus basalis magnocellularis and its relationship to dementia, Trends Neurosci., 9, 256, 10.1016/0166-2236(86)90071-8
Wanibuchi, 1989, Characterization of novel muscarinic agonists, 1-oxa-8-azaspiro[4.5]decane derivatives in biochemical and behavioral studies, Soc. Neurosci. Abstr., 15, 731
Watson, 1986, Biochemical and functional basis of putative muscarinic receptor subtypes and its implications, Trends Pharmacol. Sci. (Suppl. Subtypes of muscarinic receptors II), 46
Watson, 1982, [3H]Pirenzepine selectively identifies a high affinity population of muscarinic cholinergic receptors in the rats cerebral cortex, Life Sci., 31, 2019, 10.1016/0024-3205(82)90041-8
Watson, 1984, Subclassification of muscarinic receptors based upon the selective antagonist pirenzepine, Trends Pharmacol. Sci. (Suppl. Subtypes of muscarinic receptors), 9
Whitehouse, 1981, Alzheimer disease: evidence for selective loss of cholinergic neurons in the nucleus basalis, Ann. Neurol., 10, 122, 10.1002/ana.410100203
Whitehouse, 1982, Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain, Science, 215, 1237, 10.1126/science.7058341
Wilcock, 1982, Alzheimer's disease; correlation of cortical choline acetyltransferase activity with the severity of dementia and histological abnormalities, J. Neurol. Sci., 57, 407, 10.1016/0022-510X(82)90045-4
Yamamura, 1974, Muscarinic cholinergic binding in rat brain, 71, 1725