Polyunsaturated fatty acid biosynthesis: a microsomal-peroxisomal process

H. Sprecher1, Q. Chen1
1The Department of Medical Biochemistry, The Ohio State University Columbus, Ohio 43210, USA

Tài liệu tham khảo

Sprecher, 1995, Reevaluation of the pathways for the biosynthesis of polyunsaturated fatty acids, J Lipid Res, 36, 2471, 10.1016/S0022-2275(20)41084-3 Baykousheva, 1995, Peroxisomal-microsomal communication in unsaturated fatty acid metabolism, FEBS Lett, 367, 198, 10.1016/0014-5793(95)00565-Q Voss, 1991, The metabolism of 7,10,13,16,19-docosapentaenoic acid to 4,7,10,13,16,19-docosahexaenoic acid in rat liver is independent of a 4 desaturase, J Biol Chem, 266, 19995, 10.1016/S0021-9258(18)54882-1 Moore, 1995, Docosahexaenoic acid in human fibroblasts involves peroxisomal retroconversion of tetracosahexaenoic acid, J Lipid Res, 36, 2433, 10.1016/S0022-2275(20)39724-8 Mohammed, 1995, Re-evaluation of the pathway for the metabolism of 7,10,13,16-docosatetraenoic acid to 4,7,10,13,16-docosapentaenoic acid in the rat, Arch Biochem Biophys, 317, 179, 10.1006/abbi.1995.1151 Luthria, 1996, Regulation of the biosynthesis of 4,7,10,13,16,19-docosahexaenoic acid, J Biol Chem, 271, 16020, 10.1074/jbc.271.27.16020 Mohammed, 1997, Regulation of the biosynthesis of 4,7,10,13,16-docosapentaenoic acid, Biochem J, 326, 425, 10.1042/bj3260425 Chen, 1998, Analysis of the acyl-CoAs that accumulate during the peroxisomal β-oxidation of arachidonic acid and 6,9,12-octadecatrienoic acid, Arch Biochem Biophys, 349, 371, 10.1006/abbi.1997.0461 Baykousheva, 1994, Arachidonic acid formed by peroxisomal β-oxidation of 7,10,13,16-docosatetraenoic acid is esterified into 1-acyl-sn-glycero-3-phosphocholine by microsomes, J Biol Chem, 269, 18390, 10.1016/S0021-9258(17)32320-7 Tserng, 1991, NADPH-dependent reductive metabolism of cis-5 unsaturated fatty acids, J Biol Chem, 266, 11614, 10.1016/S0021-9258(18)99001-0 Smeland, 1992, NADPH-dependent β-oxidation of unsaturated fatty acids with double bonds extending from odd-numbered carbon atoms, 89, 6673 Chen, 1995, Isomerization of trans-2, Δ5-dienoyl-CoAs to Δ3,Δ5-dienoyl-CoAs in the β-oxidation of Δ5 unsaturated fatty acids, Blochemistry, 34, 250 Luo, 1994, Δ3,5,Δ2,4-Dienoyl-CoA isomerase from rat liver mitochondria, J Biol Chem, 269, 2384, 10.1016/S0021-9258(17)41957-0 Chen, 1994, Purification and mechanism of Δ3,Δ5-t-2,t-4-dienoyl-CoA isomerase from rat liver, Biochemistry, 33, 10527, 10.1021/bi00200a039 He, 1995, Peroxisomes contain Δ3,5,Δ2,4-dienoyl-CoA isomerase and thus possess all enzymes required for the β-oxidation of unsaturated fatty acids by a novel reductase-dependent pathway, Biochem Biophys Res Commun, 215, 15, 10.1006/bbrc.1995.2428 Luthria, 1995, Double bond removal from odd-numbered carbon atoms during peroxisomal β-oxidation of arachidonic acid requires both 2,4-dienoyl-CoA reductase and Δ3,5,Δ2,4-dienoyl-CoA isomerase, J Biol Chem, 270, 13771, 10.1074/jbc.270.23.13771 Diczfalusy, 1990, Identification of the intermediates in the peroxisomal β-oxidation of linoleic acid, Biochim Biophys Acta, 1043, 182, 10.1016/0005-2760(90)90294-8 Tserng, 1995, Oxidation of cis-5-unsaturated fatty acids in intact rat liver mitochondria: The operation of reduction pathways, Biochem J, 308, 39, 10.1042/bj3080039 Tserng, 1996, Reduction pathway of cis-5 unsaturated fatty acids in intact rat-liver and rat-heart-mitochondria: Assessment with stable-isotope-labeled substrates, Biochem J, 313, 581, 10.1042/bj3130581 Shoukry, 1998, Significance of the reductase-dependent pathway for the β-oxidation of unsaturated fatty acids with odd-numbered double bonds, J Biol Chem, 273, 6892, 10.1074/jbc.273.12.6892 Luthria, 1997, Metabolites produced during the peroxisomal β-oxidation of linoleate and arachidonate move to microsomes for conversion back to linoleate, Biochem Biophys Res Commun, 233, 438, 10.1006/bbrc.1997.6476 Horie, 1989, Existence of acetyl-CoA-dependent chain elongation system in hepatic peroxisomes of rat: effects of di-(2-ethyl-heptyl)phthalate on the activity, Arch Biochem Biophys, 274, 64, 10.1016/0003-9861(89)90415-3 Sprecher, 1968, The total synthesis and metabolism of 4-decenoate, dodeca-3,6-dienoate, tetra-5,8-dienoate and hexadeca-7,10-dienoate in the fat-deficient rat, Lipids, 3, 14, 10.1007/BF02530962 Sprecher, 1968, The synthesis and metabolism of hexadeca-4,7,10-trienoate, eicosa-8,11,14-trienoate, docosa-10,13,16-trienoate and docosa-6,9,12,15-tetraenoate in the rat, Biochim Biophys Acta, 152, 519, 10.1016/0005-2760(68)90092-1 Demar, 1996, Biosynthesis of the unsaturated 14-carbon fatty acids found on the N termini of photoreceptor-specific proteins, J Biol Chem, 271, 5007, 10.1074/jbc.271.9.5007