SARS-CoV-2 viremia is associated with distinct proteomic pathways and predicts COVID-19 outcomes

Journal of Clinical Investigation - Tập 131 Số 13 - 2021
Yijia Li1,2, Alexis M. Schneider3,4, Arnav Mehta3,5,6,2, Moshe Sade-Feldman3,5,2, Kyle R. Kays2, Matteo Gentili3, Nicole C. Charland2, Anna L.K. Gonye3,5,2, Irena Gushterova3,5,2, Hargun K. Khanna2, Thomas J. LaSalle3,5,2, Kendall M. Lavin-Parsons2, Brendan M. Lilley2, Carl L. Lodenstein2, Kasidet Manakongtreecheep3,2, Justin Margolin2, Brenna McKaig2, Blair A. Parry2, Maricarmen Rojas-López7,8, Brian C. Russo7,8, Nihaarika Sharma3,2, Jessica Tantivit3,9,2, Molly Thomas3,9,2, James Regan1, James P. Flynn1, Alexandra‐Chloé Villani3,9,2, Nir Hacohen3,5,2, Marcia B. Goldberg3,7,8,2, Michael R. Filbin3,2, Jonathan Z. Li1
1Brigham and Women's Hospital, and
2Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
3Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
4Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge Massachusetts, USA
5Center for Cancer Research, Department of Medicine, and
6Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA
7Center for Bacterial Pathogenesis, Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
8Department of Microbiology, Harvard Medical School, Boston, Massachusetts, USA.
9Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.

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