Characterization of the CD40L/Oncostatin M/Oncostatin M receptor axis as an antiviral and immunostimulatory system disrupted in chronic HCV infection

Ernst, 2004, Acquiring signalling specificity from the cytokine receptor gp130, Trends Genet, 20, 23, 10.1016/j.tig.2003.11.003

Auguste, 1997, Signaling of type II oncostatin M receptor, J Biol Chem, 272, 15760, 10.1074/jbc.272.25.15760

Larrea, 2009, Oncostatin M enhances the antiviral effects of type I interferon and activates immunostimulatory functions in liver epithelial cells, J Virol, 83, 3298, 10.1128/JVI.02167-08

Suda, 2002, Oncostatin M production by human dendritic cells in response to bacterial products, Cytokine, 17, 335, 10.1006/cyto.2002.1023

Banchereau, 2000, Immunobiology of dendritic cells, Annu Rev Immunol, 18, 767, 10.1146/annurev.immunol.18.1.767

Alpdogan, 2005, IL-7 and IL-15: therapeutic cytokines for immunodeficiency, Trends Immunol, 26, 56, 10.1016/j.it.2004.11.002

Mackall, 2011, Harnessing the biology of IL-7 for therapeutic application, Nat Rev Immunol, 11, 330, 10.1038/nri2970

Pellegrini, 2011, IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology, Cell, 144, 601, 10.1016/j.cell.2011.01.011

Jakobisiak, 2011, Interleukin 15 as a promising candidate for tumor immunotherapy, Cytokine Growth Factor Rev, 22, 99, 10.1016/j.cytogfr.2011.04.001

Alves, 2003, IL-15 induces antigen-independent expansion and differentiation of human naive CD8+ T cells in vitro, Blood, 102, 2541, 10.1182/blood-2003-01-0183

Fehniger, 2001, Interleukin 15: biology and relevance to human disease, Blood, 97, 14, 10.1182/blood.V97.1.14

Ranson, 2003, IL-15 availability conditions homeostasis of peripheral natural killer T cells, Proc Natl Acad Sci U S A, 100, 2663, 10.1073/pnas.0535482100

Budagian, 2006, IL-15/IL-15 receptor biology: a guided tour through an expanding universe, Cytokine Growth Factor Rev, 17, 259, 10.1016/j.cytogfr.2006.05.001

Han, 2011, IL-15:IL-15 receptor alpha superagonist complex: high-level co-expression in recombinant mammalian cells, purification and characterization, Cytokine, 56, 804, 10.1016/j.cyto.2011.09.028

Stonier, 2010, Trans-presentation: a novel mechanism regulating IL-15 delivery and responses, Immunol Lett, 127, 85, 10.1016/j.imlet.2009.09.009

Larrea, 2013, Dysregulation of interferon regulatory factors impairs the expression of immunostimulatory molecules in hepatitis C virus genotype 1-infected hepatocytes, Gut

Sarobe, 2002, Abnormal priming of CD4(+) T cells by dendritic cells expressing hepatitis C virus core and E1 proteins, J Virol, 76, 5062, 10.1128/JVI.76.10.5062-5070.2002

Larrea, 2006, Altered expression and activation of signal transducers and activators of transcription (STATs) in hepatitis C virus infection: in vivo and in vitro studies, Gut, 55, 1188, 10.1136/gut.2005.070060

Morishima, 2007, Preservation of intrahepatic hepatitis C virus (HCV)-specific CD4+ T cell responses despite global loss of CD4+ T cells in HCV/HIV coinfection, J Infect Dis, 196, 577, 10.1086/519386

Caux, 1994, Activation of human dendritic cells through CD40 cross-linking, J Exp Med, 180, 1263, 10.1084/jem.180.4.1263

Clarkson, 2006, The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development, Mol Endocrinol, 20, 675, 10.1210/me.2005-0392

Luquin, 2007, HCV structural proteins interfere with interferon-alpha Jak/STAT signalling pathway, Antiviral Res, 76, 194, 10.1016/j.antiviral.2007.06.004

Tanaka, 2003, Oncostatin M, a multifunctional cytokine, Rev Physiol Biochem Pharmacol, 149, 39, 10.1007/s10254-003-0013-1

Jung, 2010, Oncostatin M induces dendritic cell maturation and Th1 polarization, Biochem Biophys Res Commun, 394, 272, 10.1016/j.bbrc.2010.02.153

Znoyko, 2005, Expression of oncostatin M and its receptors in normal and cirrhotic human liver, J Hepatol, 43, 893, 10.1016/j.jhep.2005.04.020

Schoenberger, 1998, T cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions, Nature, 393, 480, 10.1038/31002

Wieland, 2013, Simultaneous detection of hepatitis C virus and interferon stimulated gene expression in infected human liver, Hepatology

Castilla, 1991, Transforming growth factors beta 1 and alpha in chronic liver disease. Effects of interferon alfa therapy, N Engl J Med, 324, 933, 10.1056/NEJM199104043241401

Walia, 2003, TGF-beta down-regulates IL-6 signaling in intestinal epithelial cells: critical role of SMAD-2, FASEB J, 17, 2130, 10.1096/fj.02-1211fje