Aetiology and resistance in bacteraemias among adult and paediatric haematology and cancer patients

Journal of Infection - Tập 68 - Trang 321-331 - 2014
Małgorzata Mikulska1, Claudio Viscoli1, Christina Orasch2, David M. Livermore3, Diana Averbuch4, Catherine Cordonnier5, Murat Akova6
1Division of Infectious Diseases, San Martino Hospital, University of Genoa, Largo R. Benzi 10, 16132 Genoa, Italy
2Infectious Diseases Service, Department of Medicine, BH-10-55, Centre Hospitalier Universitaire Vaudois, Rue du Bugon 46, CH-1011 Lausanne, Switzerland
3Norwich Medical School, University of East Anglia, Norwich NR4 7TJ, United Kingdom
4Pediatric Infectious Diseases Unit, Hadassah-Hebrew University Medical Center, Jerusalem 91120, Israel
5APHP-Henri Mondor, Hematology Department and Université Paris Est, LIC EA4393, F-94010 Créteil, France
6Department of Medicine, Section of Infectious Diseases, Hacettepe University School of Medicine, Ankara 06100, Turkey

Tài liệu tham khảo

Drgona, 2007, The need for aminoglycosides in combination with beta-lactams for high-risk, febrile neutropaenic patients with leukaemia, Eur J Cancer Suppl, 5, 13, 10.1016/j.ejcsup.2007.06.003 EORTC International Antimicrobial Therapy Cooperative Group, 1990, Gram-positive bacteraemia in granulocytopenic cancer patients, Eur J Cancer, 26, 569, 10.1016/0277-5379(90)90079-9 Klastersky, 1998, Science and pragmatism in the treatment and prevention of neutropenic infection, J Antimicrob Chemother, 41, 13, 10.1093/jac/41.suppl_4.13 Ortega, 2005, Bacterial and fungal bloodstream isolates from 796 hematopoietic stem cell transplant recipients between 1991 and 2000, Ann Hematol, 84, 40, 10.1007/s00277-004-0909-0 Collin, 2001, Evolution, incidence, and susceptibility of bacterial bloodstream isolates from 519 bone marrow transplant patients, Clin Infect Dis, 33, 947, 10.1086/322604 Haupt, 2001, Incidence of septicaemias and invasive mycoses in children undergoing treatment for solid tumours: a 12-year experience at a single Italian institution, Eur J Cancer, 37, 2413, 10.1016/S0959-8049(01)00274-X Oliveira, 2007, Epidemiology of bacteremia and factors associated with multi-drug-resistant Gram-negative bacteremia in hematopoietic stem cell transplant recipients, Bone Marrow Transplant, 39, 775, 10.1038/sj.bmt.1705677 Jacobson, 1999, Susceptibility surveillance among Gram-negative bacilli at a cancer center, Chemotherapy, 45, 325, 10.1159/000007223 Kamboj, 2010, The changing epidemiology of vancomycin-resistant Enterococcus (VRE) bacteremia in allogeneic hematopoietic stem cell transplant (HSCT) recipients, Biol Blood Marrow Transplant, 16, 1576, 10.1016/j.bbmt.2010.05.008 Almyroudis, 2005, Pre- and post-engraftment bloodstream infection rates and associated mortality in allogeneic hematopoietic stem cell transplant recipients, Transpl Infect Dis, 7, 11, 10.1111/j.1399-3062.2005.00088.x Cappellano, 2007, Epidemiology and risk factors for bloodstream infections after allogeneic hematopoietic stem cell transplantation, New Microbiol, 30, 89 Dettenkofer, 2005, Surveillance of nosocomial sepsis and pneumonia in patients with a bone marrow or peripheral blood stem cell transplant: a multicenter project, Clin Infect Dis, 40, 926, 10.1086/428046 Mikulska, 2009, Blood stream infections in allogeneic hematopoietic stem cell transplant recipients: reemergence of Gram-negative rods and increasing antibiotic resistance, Biol Blood Marrow Transplant, 15, 47, 10.1016/j.bbmt.2008.10.024 Poutsiaka, 2007, Blood stream infection after hematopoietic stem cell transplantation is associated with increased mortality, Bone Marrow Transplant, 40, 63, 10.1038/sj.bmt.1705690 Trecarichi, 2011, Multidrug resistant Pseudomonas aeruginosa bloodstream infection in adult patients with hematological malignancies, Haematologica, 96, e1, 10.3324/haematol.2010.036640 Busca, 2011, Blood stream infections after allogeneic stem cell transplantation: a single-center experience with the use of levofloxacin prophylaxis, Transpl Infect Dis, 14, 40, 10.1111/j.1399-3062.2011.00650.x Cattaneo, 2008, Recent changes in bacterial epidemiology and the emergence of fluoroquinolone-resistant Escherichia coli among patients with haematological malignancies: results of a prospective study on 823 patients at a single institution, J Antimicrob Chemother, 61, 721, 10.1093/jac/dkm514 Chen, 2010, Epidemiology of bloodstream infections in patients with haematological malignancies with and without neutropenia, Epidemiol Infect, 138, 1044, 10.1017/S0950268809991208 Chong, 2010, Cefepime-resistant Gram-negative bacteremia in febrile neutropenic patients with hematological malignancies, Int J Infect Dis, 14, e171, 10.1016/j.ijid.2010.01.004 Paul, 2007, The epidemiology of bacteremia with febrile neutropenia: experience from a single center, 1988–2004, Isr Med Assoc J, 9, 424 Yazaki, 2009, Incidence and risk factors of early bacterial infections after unrelated cord blood transplantation, Biol Blood Marrow Transplant, 15, 439, 10.1016/j.bbmt.2008.12.508 Gudiol, 2011, Bacteraemia due to multidrug-resistant Gram-negative bacilli in cancer patients: risk factors, antibiotic therapy and outcomes, J Antimicrob Chemother, 66, 657, 10.1093/jac/dkq494 Guven, 2006, Infectious complications in patients with hematological malignancies consulted by the Infectious Diseases team: a retrospective cohort study (1997–2001), Support Care Cancer, 14, 52, 10.1007/s00520-005-0836-1 Horasan, 2011, Bloodstream infections and mortality-related factors in febrile neutropenic cancer patients, Med Sci Monit, 17, CR304, 10.12659/MSM.881773 Kanafani, 2007, Bloodstream infections in febrile neutropenic patients at a tertiary care center in Lebanon: a view of the past decade, Int J Infect Dis, 11, 450, 10.1016/j.ijid.2006.12.008 Klastersky, 2007, Bacteraemia in febrile neutropenic cancer patients, Int J Antimicrob Agents, 30, S51, 10.1016/j.ijantimicag.2007.06.012 Malagola, 2008, Incidence of bacterial and fungal infections in newly diagnosed acute myeloid leukaemia patients younger than 65 yr treated with induction regimens including fludarabine: retrospective analysis of 224 cases, Eur J Haematol, 81, 354 Jathavedam, 2008, Infectious complications from high-dose chemotherapy and autologous stem cell transplantation for metastatic germ cell tumors, Biol Blood Marrow Transplant, 14, 595, 10.1016/j.bbmt.2008.02.020 Moreno, 2007, Bloodstream infections among transplant recipients: results of a nationwide surveillance in Spain, Am J Transplant, 7, 2579, 10.1111/j.1600-6143.2007.01964.x Norgaard, 2006, Risk of bacteraemia and mortality in patients with haematological malignancies, Clin Microbiol Infect, 12, 217, 10.1111/j.1469-0691.2005.01298.x Ritchie, 2007, High-risk febrile neutropenia in Auckland 2003–2004: the influence of the microbiology laboratory on patient treatment and the use of pathogen-specific therapy, Intern Med J, 37, 26, 10.1111/j.1445-5994.2006.01239.x Rolston, 2006, The spectrum of Gram-positive bloodstream infections in patients with hematologic malignancies, and the in vitro activity of various quinolones against Gram-positive bacteria isolated from cancer patients, Int J Infect Dis, 10, 223, 10.1016/j.ijid.2005.05.007 Safdar, 2006, Changing trends in etiology of bacteremia in patients with cancer, Eur J Clin Microbiol Infect Dis, 25, 522, 10.1007/s10096-006-0173-4 Trecarichi, 2009, Incidence and clinical impact of extended-spectrum-beta-lactamase (ESBL) production and fluoroquinolone resistance in bloodstream infections caused by Escherichia coli in patients with hematological malignancies, J Infect, 58, 299, 10.1016/j.jinf.2009.02.002 Tumbarello, 2009, Factors associated with mortality in bacteremic patients with hematologic malignancies, Diagn Microbiol Infect Dis, 64, 320, 10.1016/j.diagmicrobio.2009.02.008 Velasco, 2006, Comparative study of clinical characteristics of neutropenic and non-neutropenic adult cancer patients with bloodstream infections, Eur J Clin Microbiol Infect Dis, 25, 1, 10.1007/s10096-005-0077-8 Yoshida, 2011, Analysis of bacteremia/fungemia and pneumonia accompanying acute myelogenous leukemia from 1987 to 2001 in the Japan Adult Leukemia Study Group, Int J Hematol, 93, 66, 10.1007/s12185-010-0746-y Prabhash, 2010, Blood stream infections in cancer patients: a single center experience of isolates and sensitivity pattern, Indian J Cancer, 47, 184, 10.4103/0019-509X.63019 Huang, 2011 Al-Tonbary, 2011, Nosocomial infections and fever of unknown origin in pediatric hematology/oncology unit: a retrospective annual study, World J Pediatr, 7, 60, 10.1007/s12519-010-0212-1 Sayed, 2009, Profile of infections in newly diagnosed patients with acute leukemia during the induction phase of treatment, J Egypt Natl Canc Inst, 21, 315 Simon, 2008, Healthcare-associated infections in pediatric cancer patients: results of a prospective surveillance study from university hospitals in Germany and Switzerland, BMC Infect Dis, 8, 70, 10.1186/1471-2334-8-70 Laws, 2007, Trends in infections in children with malignant disease in 2000: comparison of data of 1980/81, Pediatr Hematol Oncol, 24, 343, 10.1080/08880010701391788 Katsimpardi, 2006, Infections in a pediatric patient cohort with acute lymphoblastic leukemia during the entire course of treatment, Support Care Cancer, 14, 277, 10.1007/s00520-005-0884-6 Asturias, 2010, Evaluation of six risk factors for the development of bacteremia in children with cancer and febrile neutropenia, Curr Oncol, 17, 59, 10.3747/co.v17i2.453 Bakhshi, 2008, Infections in childhood acute lymphoblastic leukemia: an analysis of 222 febrile neutropenic episodes, Pediatr Hematol Oncol, 25, 385, 10.1080/08880010802106564 Greenberg, 2005, Microbiological spectrum and susceptibility patterns of pathogens causing bacteraemia in paediatric febrile neutropenic oncology patients: comparison between two consecutive time periods with use of different antibiotic treatment protocols, Int J Antimicrob Agents, 25, 469, 10.1016/j.ijantimicag.2005.01.020 Castagnola, 2005, Bloodstream infections and invasive mycoses in children undergoing acute leukaemia treatment: a 13-year experience at a single Italian institution, Eur J Cancer, 41, 1439, 10.1016/j.ejca.2005.03.007 Castagnola, 2005, Differences in the proportions of fluoroquinolone-resistant Gram-negative bacteria isolated from bacteraemic children with cancer in two Italian centres, Clin Microbiol Infect, 11, 505, 10.1111/j.1469-0691.2005.01114.x Castagnola, 2007, A prospective study on the epidemiology of febrile episodes during chemotherapy-induced neutropenia in children with cancer or after hemopoietic stem cell transplantation, Clin Infect Dis, 45, 1296, 10.1086/522533 Castagnola, 2008, Incidence of bacteremias and invasive mycoses in children undergoing allogeneic hematopoietic stem cell transplantation: a single center experience, Bone Marrow Transplant, 41, 339, 10.1038/sj.bmt.1705921 Castagnola, 2010, Incidence of bacteremias and invasive mycoses in children with acute non-lymphoblastic leukemia: results from a multi-center Italian study, Pediatr Blood Cancer, 55, 1103, 10.1002/pbc.22750 Agyeman, 2011, Predicting bacteremia in children with cancer and fever in chemotherapy-induced neutropenia: results of the prospective multicenter SPOG 2003 FN study, Pediatr Infect Dis J, 30, e114, 10.1097/INF.0b013e318215a290 Kersun, 2005, Early bacteremia in pediatric hematopoietic stem cell transplant patients on oral antibiotic prophylaxis, Pediatr Blood Cancer, 45, 162, 10.1002/pbc.20277 Caselli, 2010, Multidrug resistant Pseudomonas aeruginosa infection in children undergoing chemotherapy and hematopoietic stem cell transplantation, Haematologica, 95, 1612, 10.3324/haematol.2009.020867 Gudiol, 2012, Changing aetiology, clinical features, antimicrobial resistance, and outcomes of bloodstream infection in neutropenic cancer patients, Clin Microbiol Infect, 19, 474, 10.1111/j.1469-0691.2012.03879.x EARSS, 2008 Spellberg, 2008, The epidemic of antibiotic-resistant infections: a call to action for the medical community from the Infectious Diseases Society of America, Clin Infect Dis, 46, 155, 10.1086/524891 Talbot, 2010, The antibiotic development pipeline for multidrug-resistant Gram-negative bacilli: current and future landscapes, Infect Control Hosp Epidemiol, 31, S55, 10.1086/655988