Human antibodies to recombinant protein constructs of Plasmodium falciparum Apical Membrane Antigen 1 (AMA1) and their associations with protection from malaria

Vaccine - Tập 23 - Trang 718-728 - 2004
Spencer D. Polley1, Tabitha Mwangi2, Clemens H.M. Kocken3, Alan W. Thomas3, Sheetij Dutta4, David E. Lanar4, Ed Remarque3, Amanda Ross2,5,6, Thomas N. Williams2, Gabrielle Mwambingu2, Brett Lowe2,5, David J. Conway1, Kevin Marsh2,5
1Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
2Kenya Medical Research Institute, Centre for Geographic Medicine Research—Coast/Wellcome Trust Collaborative Program, P.O. Box 230, Kilifi, Kenya
3BPRC, Department of Parasitology, P.O. Box 3306, 2280 GH Rijswijk, The Netherlands
4Department of Immunology, Walter Reed Army Institute of Research, Forest Glen Annex, MD 20910, USA
5Nuffield Department of Clinical Medicine, Centre for Tropical Medicine, University of Oxford, John Radcliffe Hospital, OX3 9DY, UK
6Department of Public Health and Epidemiology, Swiss Tropical Institute, Socinstrasse 57, CH-4003 Basel, Switzerland

Tài liệu tham khảo

Marsh, 1997, Host–parasite interaction and morbidity in malaria endemic areas, Philos. Trans. R. Soc. Lond. B Biol. Sci., 352, 1385, 10.1098/rstb.1997.0124 McGregor, 1963, Treatment of East African P. falciaprm with West African human gammaglobulin, Trans. R. Soc. Trop. Med. Hyg., 57, 170, 10.1016/0035-9203(63)90058-0 Cohen, 1961, Gamma globulin and acquired immunity to human malaria, Nature, 192, 265, 10.1038/192733a0 Sabchareon, 1991, Parasitologic and clinical human response to immunoglobulin administration in falciparum malaria, Am. J. Trop. Med. Hyg., 45, 297, 10.4269/ajtmh.1991.45.297 Kennedy, 2002, In vitro studies with recombinant Plasmodium falciparum apical membrane antigen 1 (AMA1): production and activity of an AMA1 vaccine and generation of a multiallelic response, Infect. Immun., 70, 6948, 10.1128/IAI.70.12.6948-6960.2002 Stowers, 2002, Vaccination of monkeys with recombinant Plasmodium falciparum apical membrane antigen 1 confers protection against blood-stage malaria, Infect. Immun., 70, 6961, 10.1128/IAI.70.12.6961-6967.2002 Healer, 2002, Independent translocation of two micronemal proteins in developing Plasmodium falciparum merozoites, Infect. Immun., 70, 5751, 10.1128/IAI.70.10.5751-5758.2002 Crewther, 1990, Plasmodium falciparum: two antigens of similar size are located in different compartments of the rhoptry, Exp. Parasitol., 70, 193, 10.1016/0014-4894(90)90100-Q Hodder, 1996, The disulfide bond structure of Plasmodium apical membrane antigen-1, J. Biol. Chem., 271, 29446, 10.1074/jbc.271.46.29446 Bannister, 2003, Plasmodium falciparum apical membrane antigen 1 (PfAMA-1) is translocated within micronemes along subpellicular microtubules during merozoite development, J. Cell Sci., 116, 3825, 10.1242/jcs.00665 Howell, 2001, Proteolytic processing and primary structure of Plasmodium falciparum apical membrane antigen-1, J. Biol. Chem., 276, 31311, 10.1074/jbc.M103076200 Dutta, 2003, Invasion-inhibitory antibodies inhibit proteolytic processing of apical membrane antigen 1 of Plasmodium falciparum merozoites, Proc. Natl. Acad. Sci. U.S.A., 100, 12295, 10.1073/pnas.2032858100 Crewther, 1996, Protective immune responses to apical membrane antigen 1 of Plasmodium chabaudi involve recognition of strain-specific epitopes, Infect. Immun., 64, 3310, 10.1128/IAI.64.8.3310-3317.1996 Cheng, 1994, Sequence analysis of the apical membrane antigen I (AMA-1) of Plasmodium vivax, Mol. Biochem. Parasitol., 65, 183, 10.1016/0166-6851(94)90127-9 Figtree, 2000, Plasmodium vivax synonymous substitution frequencies, evolution and population structure deduced from diversity in AMA 1 and MSP 1 genes, Mol. Biochem. Parasitol., 108, 53, 10.1016/S0166-6851(00)00204-8 Waters, 1991, Intra-generic conservation and limited inter-strain variation in a protective minor surface antigen of Plasmodium knowlesi merozoites, Mol. Biochem. Parasitol., 44, 141, 10.1016/0166-6851(91)90230-4 Verra, 2000, Evidence for ancient balanced polymorphism at the Apical Membrane Antigen-1 (AMA-1) locus of Plasmodium falciparum, Mol. Biochem. Parasitol., 105, 149, 10.1016/S0166-6851(99)00162-0 Polley, 2001, Strong diversifying selection on domains of the Plasmodium falciparum apical membrane antigen 1 gene, Genetics, 158, 1505, 10.1093/genetics/158.4.1505 Polley, 2003, Allele frequency based analyses robustly map sequence sites under balancing selection in a malaria vaccine candidate antigen, Genetics, 165, 555, 10.1093/genetics/165.2.555 Kocken, 2000, Molecular characterisation of Plasmodium reichenowi apical membrane antigen-1 (AMA-1), comparison with P. falciparum AMA-1, and antibody-mediated inhibition of red cell invasion, Mol. Biochem. Parasitol., 109, 147, 10.1016/S0166-6851(00)00250-4 Cortes, 2003, Geographical structure of diversity and differences between symptomatic and asymptomatic infections for Plasmodium falciparum vaccine candidate AMA1, Infect. Immun., 71, 1416, 10.1128/IAI.71.3.1416-1426.2003 Kocken, 2002, High-level expression of the Malaria blood-stage vaccine candidate Plasmodium falciparum apical membrane antigen 1 and induction of antibodies that inhibit erythrocyte invasion, Infect. Immun., 70, 4471, 10.1128/IAI.70.8.4471-4476.2002 Hodder, 2001, Specificity of the protective antibody response to apical membrane antigen 1, Infect. Immun., 69, 3286, 10.1128/IAI.69.5.3286-3294.2001 Healer, 2004, Allelic polymorphisms in apical membrane antigen-1 are responsible for evasion of antibody-mediated inhibition in Plasmodium falciparum, Mol. Microbiol., 52, 159, 10.1111/j.1365-2958.2003.03974.x Lal, 1996, Identification of T-cell determinants in natural immune responses to the Plasmodium falciparum apical membrane antigen (AMA-1) in an adult population exposed to malaria, Infect. Immun., 64, 1054, 10.1128/IAI.64.3.1054-1059.1996 Riley, 2000, Lack of association between maternal antibody and protection of African infants from malaria infection, Infect. Immun., 68, 5856, 10.1128/IAI.68.10.5856-5863.2000 Thomas, 1994, High prevalence of natural antibodies against Plasmodium falciparum 83-kilodalton apical membrane antigen (PF83/AMA-1) as detected by capture-enzyme-linked immunosorbent assay using full-length baculovirus recombinant PF83/AMA-1, Am. J. Trop. Med. Hyg., 51, 730, 10.4269/ajtmh.1994.51.730 Udhayakumar, 2001, Longitudinal study of natural immune responses to the Plasmodium falciparum apical membrane antigen (AMA-1) in a holoendemic region of malaria in western Kenya: Asembo Bay Cohort Project VIII, Am. J. Trop. Med. Hyg., 65, 100, 10.4269/ajtmh.2001.65.100 Mwangi T. Clinical epidemiology of malaria under differing levels of transmission. Ph.D. Thesis, University of Oxford, 2003. Dutta, 2002, Purification, characterization, and immunogenicity of the refolded ectodomain of the Plasmodium falciparum apical membrane antigen 1 expressed in Escherichia coli, Infect. Immun., 70, 3101, 10.1128/IAI.70.6.3101-3110.2002 Ndungu, 2002, Naturally acquired immunoglobulin (Ig)G subclass antibodies to crude asexual Plasmodium falciparum lysates: evidence for association with protection for IgG1 and disease for IgG2, Parasite Immunol., 24, 77, 10.1046/j.0141-9838.2001.00440.x Zhang, 1998, What’s the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes, JAMA, 280, 1690, 10.1001/jama.280.19.1690 Bull, 2002, Plasmodium falciparum infections are associated with agglutinating antibodies to parasite-infected erythrocyte surface antigens among healthy Kenyan children, J. Infect. Dis., 185, 1688, 10.1086/340420 al-Yaman, 1995, Assessment of the role of the humoral response to Plasmodium falciparum MSP2 compared to RESA and SPf66 in protecting Papua New Guinean children from clinical malaria, Parasite Immunol., 17, 493, 10.1111/j.1365-3024.1995.tb00920.x Bouharoun-Tayoun, 1995, Mechanisms underlying the monocyte-mediated antibody-dependent killing of Plasmodium falciparum asexual blood stages, J. Exp. Med., 182, 409, 10.1084/jem.182.2.409 Bouharoun-Tayoun, 1990, Antibodies that protect humans against Plasmodium falciparum blood stages do not on their own inhibit parasite growth and invasion in vitro, but act in cooperation with monocytes, J. Exp. Med., 172, 1633, 10.1084/jem.172.6.1633 Bouharoun-Tayoun, 1992, Plasmodium falciparum malaria: evidence for an isotype imbalance which may be responsible for delayed acquisition of protective immunity, Infect. Immun., 60, 1473, 10.1128/IAI.60.4.1473-1481.1992 Goulder, 2001, Evolution and transmission of stable CTL escape mutations in HIV infection, Nature, 412, 334, 10.1038/35085576