WT1 Maintains Adrenal-Gonadal Primordium Identity and Marks a Population of AGP-like Progenitors within the Adrenal Gland

Developmental Cell - Tập 27 - Trang 5-18 - 2013
Roberto Bandiera1,2, Valerie P.I. Vidal1,2, Fariba Jian Motamedi1,2, Michael Clarkson1,2, Isabelle Sahut-Barnola3, Alexander von Gise4,5, William T. Pu4,5, Peter Hohenstein6, Antoine Martinez3, Andreas Schedl1,2
1Institute of Biology Valrose, iBV, University of Nice Sophia-Antipolis, 06108 Nice Cedex 2, France
2INSERM UMR 1091, CNRS UMR 7277 Parc Valrose, 06108 Nice Cedex 2, France
3CNRS UMR6293, INSERM U1103, Génétique Reproduction et Développement (GReD), Clermont Université, 63170 Aubière, France
4Department of Cardiology, Children's Hospital Boston, Boston, MA 02115, USA
5Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA
6The Roslin Institute, University of Edinburgh, Easter Bush Campus, EH25 9RG Edinburgh, UK

Tài liệu tham khảo

Anderson, 1986, A bipotential neuroendocrine precursor whose choice of cell fate is determined by NGF and glucocorticoids, Cell, 47, 1079, 10.1016/0092-8674(86)90823-8 Bai, 2002, Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway, Development, 129, 4753, 10.1242/dev.129.20.4753 Bickmore, 1992, Modulation of DNA binding specificity by alternative splicing of the Wilms tumor wt1 gene transcript, Science, 257, 235, 10.1126/science.1321494 Bielinska, 2003, Mouse strain susceptibility to gonadectomy-induced adrenocortical tumor formation correlates with the expression of GATA-4 and luteinizing hormone receptor, Endocrinology, 144, 4123, 10.1210/en.2003-0126 Bielinska, 2005, Gonadotropin-induced adrenocortical neoplasia in NU/J nude mice, Endocrinology, 146, 3975, 10.1210/en.2004-1643 Bingham, 2006, Development of a steroidogenic factor 1/Cre transgenic mouse line, Genesis, 44, 419, 10.1002/dvg.20231 Cabrera, 2001, Long term outcome in adult males with classic congenital adrenal hyperplasia, J. Clin. Endocrinol. Metab., 86, 3070 Caricasole, 1996, RNA binding by the Wilms tumor suppressor zinc finger proteins, Proc. Natl. Acad. Sci. USA, 93, 7562, 10.1073/pnas.93.15.7562 Chau, 2011, Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1, PLoS Genet., 7, e1002404, 10.1371/journal.pgen.1002404 Comai, 2010, Expression patterns of the Wtx/Amer gene family during mouse embryonic development, Dev. Dyn., 239, 1867, 10.1002/dvdy.22313 Essafi, 2011, A wt1-controlled chromatin switching mechanism underpins tissue-specific wnt4 activation and repression, Dev. Cell, 21, 559, 10.1016/j.devcel.2011.07.014 França, 2013, POD-1 binding to the E-box sequence inhibits SF-1 and StAR expression in human adrenocortical tumor cells, Mol. Cell. Endocrinol., 371, 140, 10.1016/j.mce.2012.12.029 Gao, 2006, The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis, Proc. Natl. Acad. Sci. USA, 103, 11987, 10.1073/pnas.0600994103 Hammes, 2001, Two splice variants of the Wilms’ tumor 1 gene have distinct functions during sex determination and nephron formation, Cell, 106, 319, 10.1016/S0092-8674(01)00453-6 Hatano, 1996, Identical origin of adrenal cortex and gonad revealed by expression profiles of Ad4BP/SF-1, Genes Cells, 1, 663, 10.1046/j.1365-2443.1996.00254.x Hohenstein, 2006, The many facets of the Wilms’ tumour gene, WT1, Hum. Mol. Genet., 15, R196, 10.1093/hmg/ddl196 Hohenstein, 2008, High-efficiency Rosa26 knock-in vector construction for Cre-regulated overexpression and RNAi, Pathogenetics, 1, 3, 10.1186/1755-8417-1-3 Huang, 2010, Progenitor cell expansion and organ size of mouse adrenal is regulated by sonic hedgehog, Endocrinology, 151, 1119, 10.1210/en.2009-0814 Ikeda, 1994, Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases, Mol. Endocrinol., 8, 654 Johnsen, 2006, Gonadectomy in mice of the inbred strain CE/J induces proliferation of sub-capsular adrenal cells expressing gonadal marker genes, J. Endocrinol., 190, 47, 10.1677/joe.1.06750 Kennedy, 1996, An RNA recognition motif in Wilms’ tumour protein (WT1) revealed by structural modelling, Nat. Genet., 12, 329, 10.1038/ng0396-329 Kero, 2000, Elevated luteinizing hormone induces expression of its receptor and promotes steroidogenesis in the adrenal cortex, J. Clin. Invest., 105, 633, 10.1172/JCI7716 Kim, 2007, Adrenocortical cells with stem/progenitor cell properties: recent advances, Mol. Cell Endocrinol., 265–266, 10, 10.1016/j.mce.2006.12.028 King, 2009, Shh signaling regulates adrenocortical development and identifies progenitors of steroidogenic lineages, Proc. Natl. Acad. Sci. USA, 106, 21185, 10.1073/pnas.0909471106 Kreidberg, 1993, WT-1 is required for early kidney development, Cell, 74, 679, 10.1016/0092-8674(93)90515-R Larsson, 1995, Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing, Cell, 81, 391, 10.1016/0092-8674(95)90392-5 Luo, 1994, A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation, Cell, 77, 481, 10.1016/0092-8674(94)90211-9 Mesiano, 1997, Developmental and functional biology of the primate fetal adrenal cortex, Endocr. Rev., 18, 378 Moore, 1998, YAC transgenic analysis reveals Wilms’ tumour 1 gene activity in the proliferating coelomic epithelium, developing diaphragm and limb, Mech. Dev., 79, 169, 10.1016/S0925-4773(98)00188-9 Moore, 1999, YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis, Development, 126, 1845, 10.1242/dev.126.9.1845 Morohashi, 1996, Ad4BP/SF-1, a transcription factor essential for the transcription of steroidogenic cytochrome P450 genes and for the establishment of the reproductive function, FASEB J., 10, 1569, 10.1096/fasebj.10.14.9002548 Muzumdar, 2007, A global double-fluorescent Cre reporter mouse, Genesis, 45, 593, 10.1002/dvg.20335 Nachtigal, 1998, Wilms’ tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression, Cell, 93, 445, 10.1016/S0092-8674(00)81172-1 Niksic, 2004, The Wilms’ tumour protein (WT1) shuttles between nucleus and cytoplasm and is present in functional polysomes, Hum. Mol. Genet., 13, 463, 10.1093/hmg/ddh040 Sahut-Barnola, 2010, Cushing’s syndrome and fetal features resurgence in adrenal cortex-specific Prkar1a knockout mice, PLoS Genet., 6, e1000980, 10.1371/journal.pgen.1000980 Smart, 2011, De novo cardiomyocytes from within the activated adult heart after injury, Nature, 474, 640, 10.1038/nature10188 Stikkelbroeck, 2001, High prevalence of testicular adrenal rest tumors, impaired spermatogenesis, and Leydig cell failure in adolescent and adult males with congenital adrenal hyperplasia, J. Clin. Endocrinol. Metab., 86, 5721, 10.1210/jcem.86.12.8090 Tamura, 2001, Pod-1/Capsulin shows a sex- and stage-dependent expression pattern in the mouse gonad development and represses expression of Ad4BP/SF-1, Mech. Dev., 102, 135, 10.1016/S0925-4773(01)00298-2 Uotila, 1940, The early embryological development of the fetal and permanent adrenal cortex in man, Anat. Rec., 76, 183, 10.1002/ar.1090760207 Val, 2006, Identification of a novel population of adrenal-like cells in the mammalian testis, Dev. Biol., 299, 250, 10.1016/j.ydbio.2006.07.030 Val, 2007, Adrenal development is initiated by Cited2 and Wt1 through modulation of Sf-1 dosage, Development, 134, 2349, 10.1242/dev.004390 Vidal, 2000, Requirement of WT1 for gonad and adrenal development: insights from transgenic animals, Endocr. Res., 26, 1075, 10.3109/07435800009048640 Wilhelm, 2002, The Wilms tumor suppressor WT1 regulates early gonad development by activation of Sf1, Genes Dev., 16, 1839, 10.1101/gad.220102 Woolley, 1952, Adrenal tumors and other pathological changes in reciprocal crosses in mice. I. Strain DBA x strain CE and the reciprocal, Cancer Res., 12, 142 Woolley, 1953, Adrenal tumors and other pathological changes in reciprocal crosses in mice. II. An introduction to results of four reciprocal crosses, Cancer Res., 13, 231 Zhou, 2008, Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart, Nature, 454, 109, 10.1038/nature07060 Zubair, 2008, Developmental links between the fetal and adult zones of the adrenal cortex revealed by lineage tracing, Mol. Cell. Biol., 28, 7030, 10.1128/MCB.00900-08