Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome
Jerry Pelletier1,2, Wendy Bruening1, Clifford E. Kashtan3, S. Michael Mauer3, J. Carlos Manivel4, Jane E. Striegel5, Donald C. Houghton6, Claudine Junien7, Renée Habib8, Laurie Fouser9, Richard N. Fine10, Bernard L. Silverman11, Daniel A. Haber1,12, David Housman1
1Center for Cancer Research Massachusetts Institute of Technology Cambridge, Massachusetts 02139
2McGill Cancer Center McGill University Montreal, Quebec Canada H3G 1Y6
3Department of Pediatric Nephrology
4Department of Laboratory Medicine and PathologyUniversity of Minnesota Medical School Minneapolis, Minnesota 55455
5Department of Pediatrics
6Department of Pathology Oregon Health Sciences University Portland, Oregon 97201
7INSERM U73 Génétique et Pathologie Foetale
8U.192, Hôpital Necker-Enfants Malades Paris, France
9Department of Pediatrics University of Washington School of Medicine Seattle, Washington 98195
10Department of Pediatrics State University of New York at Stony Brook Stony Brook, New York 11794
11Division of Pediatric Endocrinology Children's Memorial Hospital Chicago, Illinois 60614
12Massachusetts General Hospital Cancer Center Harvard Medical School Boston, Massachusetts 02114