Nuclear pore rearrangements and nuclear trafficking in cardiomyocytes from rat and human failing hearts

Zhang, 2011, The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice, J Clin Invest, 121, 2447, 10.1172/JCI46277

Hill, 2008, Cardiac plasticity, N Engl J Med, 358, 1370, 10.1056/NEJMra072139

Perez-Terzic, 2001, Directed inhibition of nuclear import in cellular hypertrophy, J Biol Chem, 276, 20566, 10.1074/jbc.M101950200

Kehat, 2010, Molecular pathways underlying cardiac remodeling during pathophysiological stimulation, Circulation, 122, 2727, 10.1161/CIRCULATIONAHA.110.942268

Olson, 2003, Sizing up the heart: development redux in disease, Genes Dev, 17, 1937, 10.1101/gad.1110103

Görlich, 2003, Nucleocytoplasmic transport, Science, 271, 1513, 10.1126/science.271.5255.1513

Faustino, 2008, Ceramide regulation of nuclear protein import, J Lipid Res, 49, 654, 10.1194/jlr.M700464-JLR200

Faustino, 2007, RanGAP-mediated nuclear protein import in vascular smooth muscle cells is augmented by lysophosphatidylcholine, Mol Pharmacol, 71, 438, 10.1124/mol.105.021667

Chahine, 2009, Therapeutic targeting of nuclear protein import in pathological cell conditions, Pharmacol Rev, 61, 358, 10.1124/pr.108.000620

Cortés, 2010, Influence of heart failure on nucleocytoplasmic transport in human cardiomyocytes, Cardiovasc Res, 85, 464, 10.1093/cvr/cvp336

Perez-Terzic, 1999, Structural plasticity of the cardiac nuclear pore complex in response to regulators of nuclear import, Circ Res, 84, 1292, 10.1161/01.RES.84.11.1292

Hallhuber, 2006, Inhibition of nuclear import of calcineurin prevents myocardial hypertrophy, Circ Res, 99, 626, 10.1161/01.RES.0000243208.59795.d8

Lyon, 2009, Loss of T-tubules and other changes to surface topography in ventricular myocytes from failing human and rat heart, Proc Natl Acad Sci USA, 106, 6854, 10.1073/pnas.0809777106

Harding, 1992, Isolated ventricular myocytes from failing and non-failing human heart; the relation of age and clinical status of patients to isoproterenol response, J Mol Cell Cardiol, 24, 549, 10.1016/0022-2828(92)91843-T

Harding, 1988, Contractile responses of isolated adult rat and rabbit cardiac myocytes to isoproterenol and calcium, J Mol Cell Cardiol, 20, 635, 10.1016/S0022-2828(88)80121-4

Földes, 2010, Modulation of human embryonic stem cell-derived cardiomyocyte growth: a testbed for studying human cardiac hypertrophy?, J Mol Cell Cardiol, 50, 367, 10.1016/j.yjmcc.2010.10.029

McKinsey, 2007, Small-molecule therapies for cardiac hypertrophy: moving beneath the cell surface, Nat Rev Drug Discov, 6, 617, 10.1038/nrd2193

Heineke, 2006, Regulation of cardiac hypertrophy by intracellular signalling pathways, Nat Rev Mol Cell Biol, 7, 589, 10.1038/nrm1983

Bartoli, 1997, Transfer of macromolecules into living adult cardiomyocytes by microinjection, Mol Cell Biochem, 172, 103, 10.1023/A:1006867621743

Richard, 2007, Mechanical stretching stimulates smooth muscle cell growth, nuclear protein import, and nuclear pore expression through mitogen-activated protein kinase activation, J Biol Chem, 282, 23081, 10.1074/jbc.M703602200

Chahine, 2009, Oxidized LDL affects smooth muscle cell growth through MAPK-mediated actions on nuclear protein import, J Mol Cell Cardiol, 46, 431, 10.1016/j.yjmcc.2008.10.009

Chahine, 2012, Mechanical stretch enhances the oxidized LDL-induced growth, nuclear import and nuclear pore expression of smooth muscle cells through induction of endogenous HSP60 and ERK1/2 activation, Can J Plant Protect, 90, 1559

Hasegawa, 2010, High expression of Pitx-2 in the ICAT-deficient metanephros leads to developmental arrest, Acta Histochem Cytochem, 43, 51, 10.1267/ahc.09028

Lyon, 2011, SERCA 2a gene transfer decreases sarcoplasmic reticulum calcium leak and reduces ventricular arrhythmias in a model of chronic heart failure, Circ Arrhythm Electrophysiol, 4, 362, 10.1161/CIRCEP.110.961615

Monovich, 2009, Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1, Biochim Biophys Acta, 1789, 422, 10.1016/j.bbagrm.2009.04.001

del Monte, 1995, Cell geometry and contractile abnormalities of myocytes from failing human left ventricle, Cardiovasc Res, 30, 281, 10.1016/S0008-6363(95)00040-2

Nikolaev, 2010, Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation, Science, 327, 1653, 10.1126/science.1185988

Simpson, 1985, Stimulation of hypertrophy of cultured neonatal rat heart cells through an alpha 1-adrenergic receptor and induction of beating through an alpha 1- and beta 1-adrenergic receptor interaction, Circ Res, 56, 884, 10.1161/01.RES.56.6.884

Behr, 2001, Hypertensive end-organ damage and premature mortality are p38 mitogen-activated protein kinase-dependent in a rat model of cardiac hypertrophy and dysfunction, Circulation, 104, 1292, 10.1161/hc3601.094275

Dash, 2003, Differential regulation of p38 mitogen-activated protein kinase mediates gender-dependent catecholamine-induced hypertrophy, Cardiovasc Res, 57, 704, 10.1016/S0008-6363(02)00772-1

Kyoi, 2006, Opposing effect of p38 MAP kinase and JNK inhibitors on the development of heart failure in the cardiomyopathic hamster, Cardiovasc Res, 69, 888, 10.1016/j.cardiores.2005.11.015

Liu, 2005, Inhibition of p38 mitogen-activated protein kinase protects the heart against cardiac remodeling in mice with heart failure resulting from myocardial infarction, J Card Fail, 11, 74, 10.1016/j.cardfail.2004.04.004

Wenzel, 2005, p38 MAP-kinase in cultured adult rat ventricular cardiomyocytes: expression and involvement in hypertrophic signalling, Eur J Heart Fail, 7, 453, 10.1016/j.ejheart.2004.07.001

Petrich, 2004, Stress-activated MAP kinases in cardiac remodeling and heart failure: new insights from transgenic studies, Trends Cardiovasc Med, 14, 50, 10.1016/j.tcm.2003.11.002

Wenzel, 2006, Contribution of PI 3-kinase isoforms to angiotensin II- and alpha-adrenoceptor-mediated signalling pathways in cardiomyocytes, Cardiovasc Res, 71, 352, 10.1016/j.cardiores.2006.02.004

Czubryt, 2000, Hydrogen peroxide inhibition of nuclear protein import is mediated by the mitogen-activated protein kinase, ERK2, J Cell Biol, 148, 7, 10.1083/jcb.148.1.7

Cao, 2011, Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy, Proc Natl Acad Sci USA, 108, 4123, 10.1073/pnas.1015081108

Harrison, 2004, The CRM1 nuclear export receptor controls pathological cardiac gene expression, Mol Cell Biol, 24, 10636, 10.1128/MCB.24.24.10636-10649.2004