Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation

JCI insight - Tập 3 Số 1 - 2018
Sònia Guedan1, Avery D. Posey1, Carolyn E. Shaw1, Anna Wing1, Tong Da1, Prachi Patel1, Shannon E. McGettigan1, Victoria Casado‐Medrano2, Omkar U. Kawalekar1, Mireia Uribe‐Herranz3, Decheng Song1, J. Joseph Melenhorst1, Simon F. Lacey1, John Scholler1, Brian Keith1, Regina M. Young1, Carl H. June1
1Center for Cellular Immunotherapies, Department of Pathology and Laboratory Medicine.
2Department of Systems Pharmacology and Translational Therapeutics, and.
3Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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