Digital ulcers and cutaneous subsets of systemic sclerosis: Clinical, immunological, nailfold capillaroscopy, and survival differences in the Spanish RESCLE Registry

Seminars in Arthritis and Rheumatism - Tập 46 - Trang 200-208 - 2016
Carles Tolosa-Vilella1, Maria Lluisa Morera-Morales1, Carmen Pilar Simeón-Aznar2, Begoña Marí-Alfonso1, Dolores Colunga-Arguelles3, José Luis Callejas_Rubio4, Manuel Rubio-Rivas5, Maika Freire-Dapena6, Alfredo Guillén-del Castillo2, Nerea Iniesta-Arandia7, Maria Jesús Castillo-Palma8, Marivi Egurbide-Arberas9, Luis Trapiellla-Martínez10, José A Vargas-Hitos11, José Antonio Todolí-Parra12, Mónica Rodriguez-Carballeira13, Adela Marin-Ballvé14, Xavier Pla-Salas15, Juan José Rios-Blanco16, Vicent Fonollosa-Pla2
1Department of Internal Medicine, Corporació Sanitària Universitària Parc Taulí, Universidad Autónoma de Barcelona, Sabadell, Barcelona, Spain
2Department of Internal Medicine, Hospital Valld’Hebron, Barcelona, Spain
3Department of Internal Medicine, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain
4Unit of Autoimmune Systemic Diseases, Department of Internal Medicine, Hospital Clínico San Cecilio, Granada, Spain
5Department of Internal Medicine, Hospital Universitario de Bellvitge, Barcelona, Spain
6Department of Internal Medicine, Complejo Hospitalario Universitario de Vigo, Pontevedra, Spain
7Department of Autoimmune Systemic Diseases, Hospital Clinic, Barcelona, Spain
8Unit of Connective Tissue Diseases, Department of Internal Medicine, Hospital Virgen del Rocio, Sevilla, Spain
9Department of Internal Medicine, Hospital de Cruces, Barakaldo, Vizcaya, Spain
10Department of Internal Medicine, Hospital de Cabueñes, Gijón, Spain
11Department of Internal Medicine, Hospital Virgen de las Nieves, Granada, Spain
12Department of Internal Medicine, Hospital La Fe, Valencia, Spain
13Department of Internal Medicine, Hospital Universitari Mútua Terrassa, Barcelona, Spain
14Department of Internal Medicine, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain
15Consorci Hospitalari de Vic, Barcelona, Spain
16Department of Internal Medicine, Hospital La Paz, Madrid, Spain

Tài liệu tham khảo

Gabrielli, 2009, Scleroderma, N Engl J Med, 360, 1989, 10.1056/NEJMra0806188 Kayser, 2015, Autoantibodies in systemic sclerosis: unanswered questions, Front Immunol, 6, 167, 10.3389/fimmu.2015.00167 Matucci-Cerinic, 2013, Evidence that systemic sclerosis is a vascular disease, Arthritis Rheum, 65, 1953, 10.1002/art.37988 Tolosa-Vilella, 2009, Raynaud’s phenomenon, Med Clin, 132, 712 Hachulla, 2007, Natural history of ischemic digital ulcers in systemic sclerosis: single-center retrospective longitudinal study, J Rheumatol, 34, 2423 Bruni, 2015, Digital ulcers as a sentinel sign for early internal organ involvement in very early systemic sclerosis, Rheumatology, 54, 72, 10.1093/rheumatology/keu296 Baron, 2014, Consensus opinion of a North American Working Group regarding the classification of digital ulcers in systemic sclerosis, Clin Rheumatol, 33, 207, 10.1007/s10067-013-2460-7 Simeón-Aznar, 2012, Registry of the Spanish Network for Systemic Sclerosis: clinical pattern according to cutaneous subsets and immunological status, Sem Arthritis Rheum, 41, 789, 10.1016/j.semarthrit.2011.10.004 Mouthon, 2010, Impact of digital ulcers on disability and health-related quality of life in systemic sclerosis, Ann Rheum Dis, 69, 214, 10.1136/ard.2008.094193 Mihai, 2015, Digital ulcers predict a worse disease course in patients with systemic sclerosis, Ann Rheum Dis LeRoy, 2001, Criteria for the classification of early systemic sclerosis, J Rheumatol, 28, 1573 Simeón-Aznar, 2014, Systemic sclerosis sine scleroderma and limited cutaneous systemic sclerosis: similarities and differences, Clin Exp Rheumatol, 32, S33 Poormoghim, 2000, Systemic sclerosis sine scleroderma: demographic, clinical and serologic features and survival in forty-eight patients, Arthritis Rheum, 43, 444, 10.1002/1529-0131(200002)43:2<444::AID-ANR27>3.0.CO;2-G No authors listed, 1980, Preliminary criteria for the classification of systemic sclerosis (scleroderma). Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee, Arthritis Rheum, 23, 581, 10.1002/art.1780230510 van den Hoogen, 2013, classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative, Arthritis Rheum, 65, 2737, 10.1002/art.38098 Simeon, 2003, Mortality and prognostic factors in Spanish patients with systemic sclerosis, Rheumatology (Oxford), 42, 71, 10.1093/rheumatology/keg033 Hoeper, 2013, Definitions and diagnosis of pulmonary hypertension, J Am Coll Cardiol, 62, D42, 10.1016/j.jacc.2013.10.032 Coghlan, 2014, Evidence-based detection of pulmonary arterial hypertension in systemic sclerosis: the DETECT study, Ann Rheum Dis, 73, 1340, 10.1136/annrheumdis-2013-203301 Traub, 1983, Hypertension and renal failure (scleroderma renal crisis) in progressive systemic sclerosis. Review of a 25-year experience with 68 cases, Medicine (Baltimore), 62, 335, 10.1097/00005792-198311000-00001 Maricq, 1976, Skin capillary abnormalities as indicators of organ involvement in scleroderma (systemic sclerosis), Raynaud’s syndrome and dermatomyositis, Am J Med., 61, 862, 10.1016/0002-9343(76)90410-1 Sunderkötter, 2009, Comparison of patients with and without digital ulcers in systemic sclerosis: detection of possible risk factors, Br J Dermatol, 160, 835, 10.1111/j.1365-2133.2008.09004.x Tiev, 2009, Clinical features of scleroderma patients with or without prior or current ischemic digital ulcers: post-hoc analysis of a nationwide multicenter cohort (ItinérAIR-Sclérodermie), J Rheumatol, 36, 1470, 10.3899/jrheum.081044 Ferri, 2002, Systemic sclerosis: demographic, clinical, and serologic features and survival in 1012 Italian patients, Medicine, 81, 139, 10.1097/00005792-200203000-00004 Xu, 2013, Clinical characteristics of systemic sclerosis patients with digital ulcers in China, Clin Exp Rheumatol, 31, 46 Castellví, 2015, Association between nailfold capillaroscopy findings and pulmonary function tests in patients with systemic sclerosis, J Rheumatol, 42, 222, 10.3899/jrheum.140276 Sebastiani, 2012, Predictive role of capillaroscopic skin ulcer risk index in systemic sclerosis: a multicentre validation study, Ann Rheum Dis, 71, 67, 10.1136/annrheumdis-2011-200022 Walker, 2007, Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials and Research group database, Ann Rheum Dis, 66, 754, 10.1136/ard.2006.062901 Denton, 2012, Demographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry, Ann Rheum Dis, 71, 718, 10.1136/annrheumdis-2011-200631 Korn, 2004, for the RAPIDS-1 Study Group. Digital ulcers in systemic sclerosis: prevention by treatment with bosentan, an oral endothelin receptor antagonist, Arthritis Rheum, 50, 3985, 10.1002/art.20676 Khimdas, 2011, Associations with digital ulcers in a large cohort of systemic sclerosis: results from the Canadian Scleroderma Research Group registry, Arthritis Care Res, 63, 142, 10.1002/acr.20336 Hofstee, 2009, Nailfold capillary density isassociated with the presence and severity of pulmonary arterial hypertension in systemic sclerosis, Ann Rheum Dis, 68, 191, 10.1136/ard.2007.087353 Ong, 1998, Decreased nailfold capillary density in limited scleroderma with pulmonary hypertension, Asian Pac J Allergy Immunol, 16, 81 Romaniello, 2014, In systemic sclerosis patients, Bosentan is safe and effective for digital ulcer prevention and it seems to attenuate the development of pulmonary arterial hypertension, Rheumatology (Oxford), 53, 570, 10.1093/rheumatology/ket424 Avouac, 2006, Radiological hand involvement in systemic sclerosis, Ann Rheum Dis, 65, 1088, 10.1136/ard.2005.044602 Nihtyanova, 2008, Clinical burden of digital vasculopathy in limited and diffuse cutaneous systemic sclerosis, Ann Rheum Dis, 67, 120, 10.1136/ard.2007.072686 Cutolo, 2013, State of the art on nailfold capillaroscopy: a reliable diagnostic tool and putative biomarker in rheumatology?, Rheumatology (Oxford), 52, 1933, 10.1093/rheumatology/ket153 Morrisroe, 2014, The association of antiphospholipid antibodies with cardiopulmonary manifestations of systemic sclerosis, Clin Exp Rheumatol, 32, S133 Rubio-Rivas, 2014, Mortality and survival in systemic sclerosis: systematic review and meta-analysis, Sem Arthritis Rheum, 44, 208, 10.1016/j.semarthrit.2014.05.010 Vettori, 2010, Survival and death causes in 251 systemic sclerosis patients from a single Italian center, Reumatismo, 62, 202