The IL17 signaling pathway: A potential signaling pathway mediating gill hyperplasia and inflammation under ammonia nitrogen stress was identified by multi-omics analysis

Amatya, 2017, IL-17 signaling: the Yin and the Yang, Trends Immunol., 38, 310, 10.1016/j.it.2017.01.006 Baums, 2013, Establishment of a model of Streptococcus iniae meningoencephalitis in Nile tilapia (Oreochromis niloticus), J. Comp. Pathol., 149, 94, 10.1016/j.jcpa.2012.10.003 Benli, 2008, Sublethal ammonia exposure of Nile tilapia (Oreochromis niloticus L.): effects on gill, liver and kidney histology, Chemosphere, 72, 1355, 10.1016/j.chemosphere.2008.04.037 Brenner, 2013, Decoding cell death signals in liver inflammation, J. Hepatol., 59, 583, 10.1016/j.jhep.2013.03.033 Camargo, 2006, Ecological and toxicological effects of inorganic nitrogen pollution in aquatic ecosystems: a global assessment, Environ. Int., 32, 831, 10.1016/j.envint.2006.05.002 Chen, 2012, Personal omics profiling reveals dynamic molecular and medical phenotypes, Cell, 148, 1293, 10.1016/j.cell.2012.02.009 Chen, 2011, KOBAS 2.0: a web server for annotation and identification of enriched pathways and diseases, Nucleic Acids Res., 39, 316 Chen, 2022, Potential shared therapeutic and hepatotoxic mechanisms of Tripterygium wilfordii polyglycosides treating three kinds of autoimmune skin diseases by regulating IL-17 signaling pathway and Th17 cell differentiation, J. Ethnopharmacol., 296, 10.1016/j.jep.2022.115496 Cong, 2017, Gill damage and neurotoxicity of ammonia nitrogen on the clam Ruditapes philippinarum, Ecotoxicology, 26, 459, 10.1007/s10646-017-1777-4 Cong, 2021, Ammonia nitrogen exposure caused structural damages to gill mitochondria of clam Ruditapes philippinarum, Ecotoxicol. Environ. Saf., 222, 10.1016/j.ecoenv.2021.112528 Cua, 2010, Innate IL-17-producing cells: the sentinels of the immune system, Nat. Rev. Immunol., 10, 479, 10.1038/nri2800 Dalum, 2021, High-resolution, 3D imaging of the zebrafish gill-associated lymphoid tissue (GIALT) reveals a novel lymphoid structure, the amphibranchial lymphoid tissue, Front. Immunol., 12, 10.3389/fimmu.2021.769901 Dewey, 2011, RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome, BMC Bioinformatics, 12, 323, 10.1186/1471-2105-12-323 Eddy, 2010, Ammonia in estuaries and effects on fish, J. Fish Biol., 67, 1495, 10.1111/j.1095-8649.2005.00930.x Evans, 2005, The multifunctional fish gill: dominant site of gas exchange, osmoregulation, acid-base regulation, and excretion of nitrogenous waste, Physiol. Rev., 85, 97, 10.1152/physrev.00050.2003 2021 Gao, 2020, Impact of nitrite exposure on plasma biochemical parameters and immune-related responses in Takifugu rubripes, Aquat. Toxicol., 218, 10.1016/j.aquatox.2019.105362 Guo, 2022, Evaluation of ammonia nitrogen exposure in immune defenses present on spleen and head-kidney of Wuchang bream (Megalobrama amblycephala), Int. J. Mol. Sci., 23, 10.3390/ijms23063129 Hansson, 2006, The immune response in atherosclerosis: a double-edged sword, Nat. Rev. Immunol., 6, 508, 10.1038/nri1882 Haugarvoll, 2008, Identification and characterization of a novel intraepithelial lymphoid tissue in the gills of Atlantic salmon, J. Anat., 213, 202, 10.1111/j.1469-7580.2008.00943.x Hussain, 2016, Oxidative stress and inflammation: what polyphenols can do for Us?, Oxidative Med. Cell. Longev., 2016, 10.1155/2016/7432797 Kim, 2015, HISAT: a fast spliced aligner with low memory requirements, Nat. Methods, 12, 357, 10.1038/nmeth.3317 Komatsu, 2014, Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis, Nat. Med., 20, 62, 10.1038/nm.3432 Koppang, 2015 Li, 2011, Effects of chronic ammonia stress on foraging, growth, and haematological parameters of yellow catfish (Pelteobagrus fulvidraco) juveniles, Chin.J.Appl.Environ.Biol., 17, 824 Li, 2011, Cyclooxygenase-2 regulates Th17 cell differentiation during allergic lung inflammation, Am. J. Respir. Crit. Care Med., 184, 37, 10.1164/rccm.201010-1637OC Li, 2016, Ammonia toxicity induces glutamine accumulation, oxidative stress and immunosuppression in juvenile yellow catfish Pelteobagrus fulvidraco, Comp.Biochem.Physiol.C-Toxicol.Pharmacol., 183, 1, 10.1016/j.cbpc.2016.01.005 Li, 2020, Ammonia toxicity in the yellow catfish (Pelteobagrus fulvidraco): the mechanistic insight from physiological detoxification to poisoning, Fish Shellfish Immunol., 102, 195, 10.1016/j.fsi.2020.04.042 Li, 2015, Chronic ammonia toxicity induces glutamine accumulation, oxidative damage and immunosuppression of juvenile yellow catfish Pelteobagrus fulvidraco, J. Fish. China, 39, 728 Liu, 2020, Multi-omics analysis revealed crucial genes and pathways associated with black carp antiviral innate immunity, Fish Shellfish Immunol., 106, 724, 10.1016/j.fsi.2020.08.047 Liu, 2021, Effects of acute ammonia exposure and recovery on the antioxidant response and expression of genes in the Nrf2-Keap1 signaling pathway in the juvenile golden pompano (Trachinotus ovatus), Aquat. Toxicol., 240, 10.1016/j.aquatox.2021.105969 Liu, 2009, Necrotic cells induce and promote inflammatory responses in vitro, J. South. Med. Univ., 29, 4 Livak, 2002, Analysis of relative gene expression data using real-time quantitative PCR, Methods, 25, 402, 10.1006/meth.2001.1262 Ma, 2021, Multi-omics analysis reveals the glycolipid metabolism response mechanism in the liver of genetically improved farmed tilapia (GIFT, Oreochromis niloticus) under hypoxia stress, BMC Genomics, 22, 105, 10.1186/s12864-021-07410-x Pertea, 2015, StringTie enables improved reconstruction of a transcriptome from RNA-seq reads, Nat. Biotechnol., 33, 290, 10.1038/nbt.3122 Randall, 2002, Ammonia toxicity in fish, Mar. Pollut. Bull., 45, 17, 10.1016/S0025-326X(02)00227-8 Seo, 2020, Inorganic nitrogen compounds reduce immunity and induce oxidative stress in red seabream, Fish Shellfish Immunol, 104, 237, 10.1016/j.fsi.2020.05.072 Shen, 2008, Structure-function relationships in the IL-17 receptor: implications for signal transduction and therapy, Cytokine, 41, 92, 10.1016/j.cyto.2007.11.013 Sinha, 2014, Anti-oxidative defences are modulated differentially in three freshwater teleosts in response to ammonia-induced oxidative stress, PLoS One, 9, 10.1371/journal.pone.0095319 Strober, 2007, The fundamental basis of inflammatory bowel disease, J. Clin. Invest., 117, 514, 10.1172/JCI30587 Wang, 2004, Platycodin D and D3 isolated from the root of Platycodon grandiflorum modulate the production of nitric oxide and secretion of TNF-alpha in activated RAW 264.7 cells, Int. Immunopharmacol., 4, 1039, 10.1016/j.intimp.2004.04.005 Wang, 2017, Effects of high ammonia concentrations on three cyprinid fish: acute and whole-ecosystem chronic tests, Sci. Total Environ., 598, 900, 10.1016/j.scitotenv.2017.04.070 Wang, 2017, Effects of acute ammonia nitrogen stress on histopathology of gill and liver and enzyme activities of juvenile Verasper variegatus, Prog.Fish.Sci., 38, 59 Wu, 2020, Molecular control of pathogenic Th17 cells in autoimmune diseases, Int. Immunopharmacol., 80, 10.1016/j.intimp.2020.106187 Yang, 2019, Th17 cell pathogenicity and plasticity in rheumatoid arthritis, J. Leukoc. Biol., 106, 1233, 10.1002/JLB.4RU0619-197R Yu, 2020, Effect of acute exposure to ammonia and BFT alterations on Rhynchocypris lagowski: digestive enzyme, inflammation response, oxidative stress and immunological parameters, Environ. Toxicol. Pharmacol., 78, 10.1016/j.etap.2020.103380 Yue, 2010, Immune responses and expression of immune-related genes in swimming crab Portunus trituberculatus exposed to elevated ambient ammonia-N stress, Comp. Biochem. Physiol. A Mol. Integr. Physiol., 157, 246, 10.1016/j.cbpa.2010.07.013 Zhang, 2016, Effects of ammonia on growth, digestion and antioxidant capacity in juvenile yellow catfish Pelteobagrus fulvidraco (Richardson, 1846), J. Appl. Ichthyol., 32, 1205, 10.1111/jai.13203 Zhang, 2018, Effects of acute ammonia toxicity on oxidative stress, immune response and apoptosis of juvenile yellow catfish Pelteobagrus fulvidraco and the mitigation of exogenous taurine, Fish Shellfish Immunol., 79, 313, 10.1016/j.fsi.2018.05.036 Zhang, 2020, The protective effects of selenium on chronic ammonia toxicity in yellow catfish (Pelteobagrus fulvidraco), Fish Shellfish Immunol., 107, 137, 10.1016/j.fsi.2020.10.004 Zhao, 2019, Organ-specific responses to total ammonia nitrogen stress on juvenile grass carp (Ctenopharyngodon idellus), Environ. Sci. Pollut. Res. Int., 26, 10826, 10.1007/s11356-019-04524-4 Zhao, 2018, Integration of transcriptomics, proteomics, metabolomics and systems pharmacology data to reveal the therapeutic mechanism underlying Chinese herbal Bufei Yishen formula for the treatment of chronic obstructive pulmonary disease, Mol. Med. Rep., 17, 5247 Zhong, 2022, High starch in diet leads to disruption of hepatic glycogen metabolism and liver fibrosis in largemouth bass (Micropterus salmoides), which is mediated by the PI3K/Akt signaling pathway, Front. Physiol., 13, 10.3389/fphys.2022.880513 Zhong, 2021, Activation of the interleukin-23/interleukin-17 signalling pathway in autoinflammatory and autoimmune uveitis, Prog. Retin. Eye Res., 80, 10.1016/j.preteyeres.2020.100866 Zhu, 2018