The 2022 Banff Meeting Lung Report

Elizabeth N. Pavlisko1, Benjamin A. Adam2, Gerald J. Berry3, Fiorella Calabrese4, Nahir Cortes-Santiago5, Carolyn H. Glass1, Martin Goddard6, John R. Greenland7,8, Daniel Kreisel9, Deborah J. Levine10, Tereza Martinu11,12, Stijn E. Verleden13,14, S. Sam Weigt15, Antoine Roux16
1Department of Pathology, Duke University Medical Center, Durham, North Carolina, USA
2Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada
3Department of Pathology, Stanford University, Stanford, California, USA
4Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova Medical School, Padova, Italy
5Department of Pathology and Immunology, Texas Children’s Hospital, Houston, Texas, USA
6Pathology Department, Royal Papworth Hospital, NHS Trust, Papworth Everard, Cambridge, UK
7Department of Medicine, University of California, San Francisco, USA
8Veterans Affairs Health Care System, San Francisco, California, USA
9Department of Surgery, Department of Pathology and Immunology, Washington University, St. Louis, Missouri, USA
10Division of Pulmonary, Allergy, and Critical Care Medicine, Stanford University, California, USA
11Division of Respirology, Department of Medicine, University Health Network and University of Toronto, Toronto, Ontario, Canada
12Toronto Lung Transplant Program, University Health Network, Toronto, Ontario, Canada
13Lung Transplant Unit, Department of Chronic Diseases and Metabolism, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven, Belgium
14Department of ASTARC, University of Antwerp, Wilrijk, Belgium
15Division of Pulmonary, Allergy, and Critical Care Medicine, University of California Los Angeles, Los Angeles, California, USA
16Department of Respiratory Medicine, Foch Hospital, Suresnes, France

Tài liệu tham khảo

Verleden, 2019, Chronic lung allograft dysfunction: definition, diagnostic criteria, and approaches to treatment-a consensus report from the Pulmonary Council of the ISHLT, J Heart Lung Transplant, 38, 493, 10.1016/j.healun.2019.03.009 Stewart, 2007, Revision of the 1996 working formulation for the standardization of nomenclature in the diagnosis of lung rejection, J Heart Lung Transplant, 26, 1229, 10.1016/j.healun.2007.10.017 Levine, 2016, Antibody-mediated rejection of the lung: A consensus report of the International Society for Heart and Lung Transplantation, J Heart Lung Transplant, 35, 397, 10.1016/j.healun.2016.01.1223 von der Thüsen, 2018, The histomorphological spectrum of restrictive chronic lung allograft dysfunction and implications for prognosis, Mod Pathol, 31, 780, 10.1038/modpathol.2017.180 Pavlisko, 2022, Prognostic implications of and clinical risk factors for acute lung injury and organizing pneumonia after lung transplantation: data from a multicenter prospective cohort study, Am J Transplant, 22, 3002, 10.1111/ajt.17183 Calabrese, 2022, Lung allograft standardized histological analysis (LASHA) template: a research consensus proposal, J Heart Lung Transplant, 41, 1487, 10.1016/j.healun.2022.06.021 Sato, 2023, The roles of tertiary lymphoid structures in chronic diseases, Nat Rev Nephrol, 19, 525, 10.1038/s41581-023-00706-z Sato, 2009, The role of intrapulmonary de novo lymphoid tissue in obliterative bronchiolitis after lung transplantation, J Immunol, 182, 7307, 10.4049/jimmunol.0803606 Prop, 1985, Lung allograft rejection in the rat. II. Specific immunological properties of lung grafts, Transplantation, 40, 126, 10.1097/00007890-198508000-00003 Hasegawa, 1999, The significance of bronchus-associated lymphoid tissue in human lung transplantation: is there an association with acute and chronic rejection?, Transplantation, 67, 381, 10.1097/00007890-199902150-00007 Martinu, 2019, Spectrum of chronic lung allograft pathology in a mouse minor-mismatched orthotopic lung transplant model, Am J Transplant, 19, 247, 10.1111/ajt.15167 Watanabe, 2019, A B cell-dependent pathway drives chronic lung allograft rejection after ischemia-reperfusion injury in mice, Am J Transplant, 19, 3377, 10.1111/ajt.15550 Misumi, 2020, Humoral immune responses mediate the development of a restrictive phenotype of chronic lung allograft dysfunction, JCI Insight, 5, 10.1172/jci.insight.136533 Li, 2012, Lung transplant acceptance is facilitated by early events in the graft and is associated with lymphoid neogenesis, Mucosal Immunol, 5, 544, 10.1038/mi.2012.30 Li, 2019, Bronchus-associated lymphoid tissue-resident Foxp3+ T lymphocytes prevent antibody-mediated lung rejection, J Clin Invest, 129, 556, 10.1172/JCI122083 Li, 2020, Lymphatic drainage from bronchus-associated lymphoid tissue in tolerant lung allografts promotes peripheral tolerance, J Clin Invest, 130, 6718, 10.1172/JCI136057 Glass, 2022, The role of machine learning in cardiovascular pathology, Can J Cardiol, 38, 234, 10.1016/j.cjca.2021.11.008 Davis, 2020, Detecting acute cellular rejection in lung transplant biopsies by artificial intelligence: a novel deep learning approach, J Heart Lung Transplant, 39, S501, 10.1016/j.healun.2020.01.100 Gotlieb, 2022, The promise of machine learning applications in solid organ transplantation, NPJ Digit Med, 5, 89, 10.1038/s41746-022-00637-2 Levy, 2020, Risk assessment of chronic lung allograft dysfunction phenotypes: validation and proposed refinement of the 2019 International Society for Heart and Lung Transplantation classification system, J Heart Lung Transplant, 39, 761, 10.1016/j.healun.2020.04.012 Saito, 2016, Low-dose computed tomography volumetry for subtyping chronic lung allograft dysfunction, J Heart Lung Transplant, 35, 59, 10.1016/j.healun.2015.07.005 Weigt, 2022, Quantitative image analysis at chronic lung allograft dysfunction onset predicts mortality, Transplantation, 106, 1253, 10.1097/TP.0000000000003950 McInnis, 2022, Chronic lung allograft dysfunction phenotype and prognosis by machine learning CT analysis, Eur Respir J, 60, 2101652, 10.1183/13993003.01652-2021 Verleden, 2016, Parametric response mapping of bronchiolitis obliterans syndrome progression after lung transplantation, Am J Transplant, 16, 3262, 10.1111/ajt.13945 Belloli, 2021, Radiographic graft surveillance in lung transplantation: prognostic role of parametric response mapping, Am J Respir Crit Care Med, 204, 967, 10.1164/rccm.202012-4528OC Rademacher, 2014, Safety and efficacy of outpatient bronchoscopy in lung transplant recipients – a single centre analysis of 3,197 procedures, Transplant Res, 3, 11, 10.1186/2047-1440-3-11 Weigt, 2019, Usefulness of gene expression profiling of bronchoalveolar lavage cells in acute lung allograft rejection, J Heart Lung Transplant, 38, 845, 10.1016/j.healun.2019.05.001 Shino, 2018, The prognostic importance of bronchoalveolar lavage fluid CXCL9 during minimal acute rejection on the risk of chronic lung allograft dysfunction, Am J Transplant, 18, 136, 10.1111/ajt.14397 Shino, 2013, CXCR3 ligands are associated with the continuum of diffuse alveolar damage to chronic lung allograft dysfunction, Am J Respir Crit Care Med, 188, 1117, 10.1164/rccm.201305-0861OC Shino, 2017, The prognostic importance of CXCR3 chemokine during organizing pneumonia on the risk of chronic lung allograft dysfunction after lung transplantation, PLOS ONE, 12, 10.1371/journal.pone.0180281 Shino, 2022, The allograft injury marker CXCL9 determines prognosis of anti-HLA antibodies after lung transplantation, Am J Transplant, 22, 565, 10.1111/ajt.16827 Levy, 2021, Bronchoalveolar lavage cytokine-based risk stratification of minimal acute rejection in clinically stable lung transplant recipients, J Heart Lung Transplant, 40, 1540, 10.1016/j.healun.2021.05.017 Shino, 2021, Correlation between BAL CXCR3 chemokines and lung allograft histopathologies: A multicenter study, Am J Transplant, 21, 3401, 10.1111/ajt.16601 Shino, 2022, Plasma CXCL9 and CXCL10 at allograft injury predict chronic lung allograft dysfunction, Am J Transplant, 22, 2169, 10.1111/ajt.17108 Dugger, 2021, Chronic lung allograft dysfunction small airways reveal a lymphocytic inflammation gene signature, Am J Transplant, 21, 362, 10.1111/ajt.16293 Chambers, 2011, A novel approach to the assessment of lymphocytic bronchiolitis after lung transplantation—transbronchial brush, J Heart Lung Transplant, 30, 544, 10.1016/j.healun.2010.10.018 Banerjee, 2011, The airway epithelium is a direct source of matrix degrading enzymes in bronchiolitis obliterans syndrome, J Heart Lung Transplant, 30, 1175, 10.1016/j.healun.2011.06.007 Greenland, 2019, Gene signatures common to allograft rejection are associated with lymphocytic bronchitis, Clin Transplant, 33, 10.1111/ctr.13515 Iasella, 2021, Type-1 immunity and endogenous immune regulators predominate in the airway transcriptome during chronic lung allograft dysfunction, Am J Transplant, 21, 2145, 10.1111/ajt.16360 Agbor-Enoh, 2019, Donor-derived cell-free DNA predicts allograft failure and mortality after lung transplantation, EBiomedicine, 40, 541, 10.1016/j.ebiom.2018.12.029 Keller, 2022, Biological variation of donor-derived cell-free DNA in stable lung transplant recipients, J Appl Lab Med, 7, 901, 10.1093/jalm/jfab171 Jang, 2021, Donor-derived cell-free DNA accurately detects acute rejection in lung transplant patients, a multicenter cohort study, J Heart Lung Transplant, 40, 822, 10.1016/j.healun.2021.04.009 Keller, 2022, Donor-derived cell-free DNA as a composite marker of acute lung allograft dysfunction in clinical care, J Heart Lung Transplant, 41, 458, 10.1016/j.healun.2021.12.009 Halloran, 2019, Molecular assessment of rejection and injury in lung transplant biopsies, J Heart Lung Transplant, 38, 504, 10.1016/j.healun.2019.01.1317 Halloran, 2020, Molecular phenotyping of rejection-related changes in mucosal biopsies from lung transplants, Am J Transplant, 20, 954, 10.1111/ajt.15685 Halloran, 2020, Molecular T-cell‒mediated rejection in transbronchial and mucosal lung transplant biopsies is associated with future risk of graft loss, J Heart Lung Transplant, 39, 1327, 10.1016/j.healun.2020.08.013 Parkes, 2022, Transcripts associated with chronic lung allograft dysfunction in transbronchial biopsies of lung transplants, Am J Transplant, 22, 1054, 10.1111/ajt.16895 Mengel, 2020, Banff 2019 Meeting Report: molecular diagnostics in solid organ transplantation-Consensus for the Banff Human Organ Transplant (B-HOT) gene panel and open source multicenter validation, Am J Transplant, 20, 2305, 10.1111/ajt.16059