Differences in ionotropic glutamate receptor subunit expression are not responsible for strain-dependent susceptibility to excitotoxin-induced injury

Beal, 1992, Mechanisms of excitotoxicity in neurologic diseases, FASEB J., 6, 3338, 10.1096/fasebj.6.15.1464368 Ben-Ari, 1984, Kainic acid seizure syndrome and binding sites in developing rats, Brain Res., 316, 284, 10.1016/0165-3806(84)90314-6 Ben-Ari, 1985, Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy, Neuroscience, 14, 375, 10.1016/0306-4522(85)90299-4 Bettler, 1995, Review: neurotransmitter receptors. II. AMPA and kainate receptors, Neuropharmacology, 34, 123, 10.1016/0028-3908(94)00141-E Bradford, 1995, Glutamate, GABA and epilepsy, Prog. Neurobiol., 47, 477, 10.1016/0301-0082(95)00030-5 Choi, 1988, Glutamate neurotoxicity and diseases of the nervous system, Neuron, 1, 623, 10.1016/0896-6273(88)90162-6 Choi, 1988, Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage, Trends Neurosci., 11, 465, 10.1016/0166-2236(88)90200-7 Choi, 1996, Ischemia-induced neuronal apoptosis, Curr. Opin. Neurobiol., 6, 667, 10.1016/S0959-4388(96)80101-2 Clifford, 1990, Ketamine, phencyclidine, and MK-801 protect against kainic acid-induced seizure-related brain damage, Epilepsia, 31, 382, 10.1111/j.1528-1157.1990.tb05492.x Conti, 1999, Shaping excitation at glutamatergic synapses, Trends Neurosci., 22, 451, 10.1016/S0166-2236(99)01445-9 Dichter, 1994, Emerging insights into mechanisms of epilepsy: implications for new antiepileptic drug development, Epilepsia, 35, S51, 10.1111/j.1528-1157.1994.tb05956.x Doble, 1999, The role of excitotoxicity in neurodegenerative disease: implications for therapy, Pharmacol. Ther., 81, 163, 10.1016/S0163-7258(98)00042-4 Friedman, 1994, Kainate-induced status epilepticus alters glutamate and GABAA receptor gene expression in adult rat hippocampus: an in situ hybridization study, J. Neurosci., 14, 2667, 10.1523/JNEUROSCI.14-05-02697.1994 Friedman, 1997, Developmental regulation of glutamate and GABAA receptor gene expression in rat hippocampus following kainate-induced status epilepticus, Dev. Neurosci., 19, 529, 10.1159/000111257 Friedman, 1998, Selective reduction of GluR2 protein in adult hippocampal CA3 neurons following status epilepticus but prior to cell loss, Hippocampus, 8, 511, 10.1002/(SICI)1098-1063(1998)8:5<511::AID-HIPO9>3.0.CO;2-W Gall, 1990, Levels of mRNA for a putative kainate receptor are affected by seizures, Proc. Natl. Acad. Sci. USA, 87, 7463, 10.1073/pnas.87.19.7643 Gerlai, 1996, Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?, Trends Neurosci., 19, 177, 10.1016/S0166-2236(96)20020-7 Gerlai, 2001, LTP: variation between inbred mouse strains, Trends Neurosci., 24, 75, 10.1016/S0166-2236(00)01750-1 Gill, 2002, Pharmacological characterization of Ro 63-1908 (1-[2-(4-hydroxy-phenoxy)-ethyl]-4-(4-methyl-benzyl)-piperidin-4-ol), a novel subtype-selective N-methyl-d-aspartate antagonist, J. Pharmacol. Exp. Ther., 302, 940, 10.1124/jpet.102.034322 Grooms, 2000, Status epilepticus decreases glutamate receptor 2 mRNA and protein expression in hippocampal pyramidal cells before neuronal death, Proc. Natl. Acad. Sci. USA, 97, 3631, 10.1073/pnas.050586497 Hicks, 1996, Amino acids as the source of considerable excitation in cerebral cortex, Can. J. Physiol. Pharmacol., 74, 341, 10.1139/y96-046 Hollmann, 1994, Cloned glutamate receptors, Annu. Rev. Neurosci., 17, 31, 10.1146/annurev.ne.17.030194.000335 Hollmann, 1991, Ca2+ permeability of KA-AMPA-gated glutamate receptor channels depends on subunit composition, Science, 252, 851, 10.1126/science.1709304 Hume, 1991, Identification of a site in glutamate receptor subunits that controls calcium permeability, Science, 253, 1028, 10.1126/science.1653450 Huntley, 1994, Cellular and synaptic localization of NMDA and non-NMDA receptor subunits in neocortex: organizational features related to cortical circuitry, function and disease, Trends Neurosci., 17, 428, 10.1016/0166-2236(94)90158-9 Kamatchi, 1995, GABAA receptor beta 1, beta 2, and beta 3 subunits: comparisons in DBA/2J and C57BL/6J mice, Biochim. Biophys. Acta, 1261, 134, 10.1016/0167-4781(95)00009-6 Kest, 1998, Differences in delta opioid receptor antinociception, binding, and mRNA levels between BALB/c and CXBK mice, Brain Res., 805, 131, 10.1016/S0006-8993(98)00696-9 Kovacs, 1996, Protection against non-NMDA receptor-mediated excitotoxicity by GYKI 52466 in mature telencephalic cultures of the rat, Neurobiology, 4, 59 Kraus, 1994, Kindling induces the long-lasting expression of a novel population of NMDA receptors in hippocampal region CA3, J. Neurosci., 14, 4196, 10.1523/JNEUROSCI.14-07-04196.1994 Kürschner, 1998, Kainate and AMPA receptor binding in seizure-prone and seizure-resistant inbred mouse strains, Brain Res., 780, 1, 10.1016/S0006-8993(97)01081-0 Lason, 1997, Seizure-related changes in the glutamate R2 and R5 receptor genes expression in the rat hippocampal formation, J. Neural Transm., 104, 125, 10.1007/BF01273175 Lehmann, 1993, 7-Chlorokynurenate prevents NMDA-induced and kainate-induced striatal lesions, Brain Res., 620, 1, 10.1016/0006-8993(93)90263-M Lipton, 1994, Excitatory amino acids as a final common pathway for neurologic disorders, N. Engl. J. Med., 330, 613, 10.1056/NEJM199403033300907 Marianowski, 1995, N-Methyl-d-aspartate receptor subunits NR1 and NR2C are overexpressed in the inferior colliculus of audiogenic mice, Neurosci. Lett., 189, 190, 10.1016/0304-3940(95)11454-5 Marks, 1996, ST/b and DBA/2 mice differ in brain alpha-bungarotoxin binding and alpha 7 nicotinic receptor subunit mRNA levels: a quantitative autoradiographic analysis, Mol. Brain Res., 39, 207, 10.1016/0169-328X(96)00027-7 Massieu, 1993, A comparative analysis of the neuroprotective properties of competitive and uncompetitive N-methyl-d-aspartate receptor antagonists in vivo: implications for the process of excitotoxic degeneration and its therapy, Neuroscience, 55, 883, 10.1016/0306-4522(93)90305-Y Mathern, 1998, Hippocampal AMPA and NMDA mRNA levels and subunit immunoreactivity in human temporal lobe epilepsy patients and a rodent model of chronic mesial limbic epilepsy, Epilepsy Res., 32, 154, 10.1016/S0920-1211(98)00048-5 Mattson, 1996, Excitotoxicity and excitoprotection in vitro, 1 Meldrum, 1990, Excitatory amino acid neurotoxicity and neurodegenerative disease, Trends Pharmacol. Sci., 11, 379, 10.1016/0165-6147(90)90184-A Meldrum, 1994, The role of glutamate in epilepsy and other CNS disorders, Neurology, 44, S14 Meldrum, 2000, Glutamate as a neurotransmitter in the brain: review of physiology and pathology, J. Nutr., 130, 1007S, 10.1093/jn/130.4.1007S Mikuni, 1999, Increased NR1-NR2A/B coassembly as a mechanism for rat chronic hippocampal epilepsy, Neurosci. Lett., 267, 165, 10.1016/S0304-3940(99)00355-9 Mikuni, 2000, NMDAR1 receptor proteins and mossy fibers in the fascia dentate during rat kainate hippocampal epileptogenesis, Exp. Neurol., 163, 271, 10.1006/exnr.2000.7356 Monyer, 1989, Glucose deprivation neuronal injury in cortical culture, Brain Res., 483, 347, 10.1016/0006-8993(89)90179-0 Monyer, 1994, Developmental and regional expression in the rat brain and functional properties of four NMDA receptors, Neuron, 12, 529, 10.1016/0896-6273(94)90210-0 Nadler, 1978, Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells, Nature, 271, 676, 10.1038/271676a0 Nadler, 1980, Loss and reacquisition of hippocampal synapses after selective destruction of CA3–CA4 afferents with kainic acid, Brain Res., 191, 387, 10.1016/0006-8993(80)91289-5 Nadler, 1980, Kainic acid neurotoxicity toward hippocampal formation: dependence on specific excitatory pathways, Brain Res., 195, 47, 10.1016/0006-8993(80)90865-3 Nadler, 1981, Kainic acid as a tool for the study of temporal lobe epilepsy, Life Sci., 29, 2031, 10.1016/0024-3205(81)90659-7 Nakanishi, 1992, Molecular diversity of glutamate receptors and implications for brain function, Science, 258, 597, 10.1126/science.1329206 Ng, 1994, Genotypic differences in brain dopamine receptor function in the DBA/2J and C57BL/6J inbred mouse strains, Eur. J. Pharmacol., 263, 349, 10.1016/0922-4106(94)90043-4 Obenaus, 1993, Loss of glutamate decarboxylase mRNA-containing neurons in the rat dentate gyrus following pilocarpine-induced seizures, J. Neurosci., 13, 4470, 10.1523/JNEUROSCI.13-10-04470.1993 Ozawa, 1998, Glutamate receptors in the mammalian central nervous system, Prog. Neurobiol., 54, 581, 10.1016/S0301-0082(97)00085-3 Pollard, 1993, Alterations of the GluR-B AMPA receptor subunit flip/flop expression in kainate-induced epilepsy and ischemia, Neuroscience, 57, 545, 10.1016/0306-4522(93)90004-Y Prehn, 1995, Are NMDA or AMPA/kainate receptor antagonists more efficacious in the delayed treatment of excitotoxic neuronal injury?, Eur. J. Pharmacol., 292, 179 Puchalski, 1994, Selective RNA editing and subunit assembly of native glutamate receptors, Neuron, 13, 131, 10.1016/0896-6273(94)90464-2 Racine, 1972, Modification of seizure activity by electrical stimulation. II. Motor seizure, Electroencephalogr. Clin. Neurophysiol., 32, 281, 10.1016/0013-4694(72)90177-0 Reilly, 2000, GABA (A) receptor beta (2) subunit mRNA content is differentially regulated in ethanol-dependent DBA/2J and C57BL/6J mice, Neurochem. Int., 37, 443, 10.1016/S0197-0186(00)00055-3 Ribak, 1979, Inhibitory, GABAergic nerve terminals decrease at sites of focal epilepsy, Science, 205, 211, 10.1126/science.109922 Rogers, 1998, Glutamate receptor GluR1 expression is altered selectively by chronic audiogenic seizures in the Frings mouse brain, J. Neurobiol., 35, 209, 10.1002/(SICI)1097-4695(199805)35:2<209::AID-NEU7>3.0.CO;2-8 Rothman, 1987, Excitotoxicity and the NMDA receptor, Trends Neurosci., 10, 299, 10.1016/0166-2236(87)90177-9 Schauwecker, 1997, Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches, Proc. Natl. Acad. Sci. USA, 94, 4103, 10.1073/pnas.94.8.4103 Schauwecker, 2000, Genetic dissection of the signals that induce synaptic reorganization, Exp. Neurol., 161, 139, 10.1006/exnr.1999.7251 Schauwecker, 2000, Seizure-induced neuronal death is associated with induction of c-Jun N-terminal kinase and is dependent on genetic background, Brain Res., 884, 116, 10.1016/S0006-8993(00)02888-2 Schauwecker, 2002, Complications associated with genetic background effects in models of experimental epilepsy, Prog. Brain Res., 135, 139, 10.1016/S0079-6123(02)35014-3 P.E. Schauwecker, Modulation of cell death by mouse genotype: differential vulnerability to excitatory amino acid induced lesions, Exp. Neurol (2002) in press. Schoepp, 1996, Selective protection against AMPA- and kainate-evoked neurotoxicity by (3S,4aR,6R,8aR)-6-[2-(1(2)H-tetrazole-5-yl)ethyl]decahyd roisoquinoline-3-carboxylic acid (LY293558) and its racemate (LY215490), J. Neural Transm., 103, 905, 10.1007/BF01291781 Schwob, 1980, Widespread patterns of neuronal damage following systemic or intracerebral injections of kainic acid: a histological study, Neuroscience, 9, 991, 10.1016/0306-4522(80)90181-5 Seeburg, 1993, The TINS/TiPS lecture. The molecular biology of mammalian glutamate receptor channels, Trends Neurosci., 16, 359, 10.1016/0166-2236(93)90093-2 Sogawa, 2001, Timing of cognitive deficits following neonatal seizures: relationship to histological changes in the hippocampus, Dev. Brain Res., 131, 73, 10.1016/S0165-3806(01)00265-6 Sommer, 1991, RNA editing in brain controls a determinant of ion flow in glutamate-gated channels, Cell, 67, 11, 10.1016/0092-8674(91)90568-J Sommer, 1992, Glutamate receptor channels—novel properties and new clones, Trends Pharmacol. Sci., 13, 291, 10.1016/0165-6147(92)90088-N Sommer, 2001, Kainate-induced epilepsy alters protein expression of AMPA receptor subunits GluR1, GluR2 and AMPA receptor binding protein in the rat hippocampus, Acta Neuropathol., 101, 460, 10.1007/s004010000310 Sperk, 1983, Kainic acid induced seizures: neurochemical and histopathological changes, Neuroscience, 10, 1301, 10.1016/0306-4522(83)90113-6 Virgili, 1992, Protection from kainic acid neuropathological syndrome by NMDA receptor antagonists: effect of MK-801 and CGP 39551 on neurotransmitter and glial markers, Neuropharmacology, 31, 469, 10.1016/0028-3908(92)90085-4 Wenthold, 1992, Immunochemical characterization of the non-NMDA glutamate receptor using subunit-specific antibodies. Evidence for a hetero-oligomeric structure in rat brain, J. Biol. Chem., 267, 501, 10.1016/S0021-9258(18)48523-7