Multifunctional electrospun nanofibers for wound application – Novel insights into the control of drug release and antimicrobial activity

Sun, 2014, bFGF-grafted electrospun fibrous scaffolds via poly (dopamine) for skin wound healing, J. Mater. Chem. B, 2, 3636, 10.1039/C3TB21814G Said, 2011, Antimicrobial PLGA ultrafine fibers: interaction with wound bacteria, Eur. J. Pharm. Biopharm., 79, 108, 10.1016/j.ejpb.2011.03.002 Ignatova, 2009, Electrospun non-woven nanofibrous hybrid mats based on chitosan and PLA for wound-dressing applications, Macromol. Biosci., 9, 102, 10.1002/mabi.200800189 Contardi, 2017, Transparent ciprofloxacin-povidone antibiotic films and nanofiber mats as potential skin and wound care dressings, Eur. J. Pharm. Sci., 104, 133, 10.1016/j.ejps.2017.03.044 Atiyeh, 2007, Effect of silver on burn wound infection control and healing: review of the literature, Burns, 33, 139, 10.1016/j.burns.2006.06.010 Azuma, 2015, Chitin, chitosan, and its derivatives for wound healing: Old and new materials, J. Funct. Biomater., 6, 104, 10.3390/jfb6010104 Min, 2004, Chitin and chitosan nanofibers: electrospinning of chitin and deacetylation of chitin nanofibers, Polymer, 45, 7137, 10.1016/j.polymer.2004.08.048 Wang, 2017, Functional electrospun fibers for the treatment of human skin wounds, Eur. J. Pharm. Biopharm., 119, 283, 10.1016/j.ejpb.2017.07.001 Ru, 2015, Suspended, shrinkage-free, electrospun PLGA nanofibrous scaffold for skin tissue engineering, ACS Appl. Mater. Interf., 7, 10872, 10.1021/acsami.5b01953 Planz, 2016, Three-dimensional hierarchical cultivation of human skin cells on bio-adaptive hybrid fibers, Integr. Biol., 8, 775, 10.1039/C6IB00080K Tığlı, 2011, Cellular behavior on epidermal growth factor (EGF)-immobilized PCL/gelatin nanofibrous scaffolds, J. Biomater. Sci. Polym. Ed., 22, 207, 10.1163/092050609X12591500475424 Liu, 2010, Electrospun PLGA/collagen nanofibrous membrane as early-stage wound dressing, J. Membr. Sci., 355, 53, 10.1016/j.memsci.2010.03.012 Semnani, 2017, Evaluation of PCL/chitosan electrospun nanofibers for liver tissue engineering, Int. J. Polym. Mater. Polym. Biomater., 66, 149, 10.1080/00914037.2016.1190931 Ozkan, 2018, Antibacterial performance of PCL-chitosan core-shell scaffolds, J. Nanosci. Nanotechnol., 18, 2415, 10.1166/jnn.2018.14378 Tardajos, 2018, Chitosan functionalized poly-ε-caprolactone electrospun fibers and 3D printed scaffolds as antibacterial materials for tissue engineering applications, Carbohydr. Polym., 191, 127, 10.1016/j.carbpol.2018.02.060 Urbanek, 2017, The effect of polarity in the electrospinning process on PCL/chitosan nanofibres' structure, properties and efficiency of surface modification, Polymer, 124, 168, 10.1016/j.polymer.2017.07.064 Neves, 2011, Chitosan/Poly(ɛ-caprolactone) blend scaffolds for cartilage repair, Biomaterials, 32, 1068, 10.1016/j.biomaterials.2010.09.073 Liverani, 2017, Incorporation of bioactive glass nanoparticles in electrospun PCL/chitosan fibers by using benign solvents, Bioact. Mater., 3, 55, 10.1016/j.bioactmat.2017.05.003 Van der Schueren, 2012, Polycaprolactone/chitosan blend nanofibres electrospun from an acetic acid/formic acid solvent system, Carbohydr. Polym., 88, 1221, 10.1016/j.carbpol.2012.01.085 Malheiro, 2010, New poly(ε-caprolactone)/chitosan blend fibers for tissue engineering applications, Acta Biomater., 6, 418, 10.1016/j.actbio.2009.07.012 Boukamp, 1988, Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line, J. Cell Biol., 106, 761, 10.1083/jcb.106.3.761 Planz, 2017, Establishment of a cell-based wound healing assay for bio-relevant testing of wound therapeutics, J. Pharmacol. Toxicol. Methods, 89, 19, 10.1016/j.vascn.2017.10.003 Shalumon, 2010, Single step electrospinning of chitosan/poly (caprolactone) nanofibers using formic acid/acetone solvent mixture, Carbohydr. Polym., 80, 413, 10.1016/j.carbpol.2009.11.039 Pelipenko, 2013, The topography of electrospun nanofibers and its impact on the growth and mobility of keratinocytes, Eur. J. Pharm. Biopharm., 84, 401, 10.1016/j.ejpb.2012.09.009 Smith, 2009, Nanostructured polymer scaffolds for tissue engineering and regenerative medicine, WIRESNanomed. Nanobiotechnol., 1, 226, 10.1002/wnan.26 Ebner, 2002, Topical use of dexpanthenol in skin disorders, Am. J. Clin. Dermatol., 3, 427, 10.2165/00128071-200203060-00005 Arima, 2007, Effect of wettability and surface functional groups on protein adsorption and cell adhesion using well-defined mixed self-assembled monolayers, Biomaterials, 28, 3074, 10.1016/j.biomaterials.2007.03.013 Seif, 2015, Overcoming drug crystallization in electrospun fibers – elucidating key parameters and developing strategies for drug delivery, Int. J. Pharm., 478, 390, 10.1016/j.ijpharm.2014.11.045 Howling, 2001, The effect of chitin and chitosan on the proliferation of human skin fibroblasts and keratinocytes in vitro, Biomaterials, 22, 2959, 10.1016/S0142-9612(01)00042-4 Wiegand, 2010, Molecular-weight-dependent toxic effects of chitosans on the human keratinocyte cell line HaCaT, Skin Pharmacol. Physiol., 23, 164, 10.1159/000276996 James, 2008, Biofilms in chronic wounds, Wound Repair Regen., 16, 37, 10.1111/j.1524-475X.2007.00321.x Trøstrup, 2013, What is new in the understanding of non healing wounds epidemiology, pathophysiology, and therapies, Ulcers, 2013, 10.1155/2013/625934