A Phase II study of Bcl-2 antisense (oblimersen sodium) combined with gemtuzumab ozogamicin in older patients with acute myeloid leukemia in first relapse
Tài liệu tham khảo
Estey, 2000, How I treat older patients with AML, Blood, 96, 1670, 10.1182/blood.V96.5.1670
Berger, 2002, Licensure of gemtuzumab ozogamicin for the treatment of selected patients 60 years of age or older with acute myeloid leukemia in first relapse, Invest New Drugs, 20, 395, 10.1023/A:1020658028082
Bross, 2001, Approval summary: gemtuzumab ozogamicin in relapsed acute myeloid leukemia, Clin Cancer Res, 7, 1490
Larson, 2002, Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin), Leukemia, 16, 1627, 10.1038/sj.leu.2402677
Karakas, 1998, High expression of bcl-2 mRNA as a determinant of poor prognosis in acute myeloid leukemia, Ann Oncol, 9, 159, 10.1023/A:1008255511404
Reed, 2003, Apoptosis-targeted therapies for cancer, Cancer Cell, 3, 17, 10.1016/S1535-6108(02)00241-6
Wu, 1996, Apoptotic death of tumor cells correlates with chemosensitivity, independent of p53 or bcl-2, Clin Cancer Res, 2, 623
Reed, 1999, Dysregulation of apoptosis in cancer, J Clin Oncol, 17, 2941, 10.1200/JCO.1999.17.9.2941
Cory, 2003, The Bcl-2 family: roles in cell survival and oncogenesis, Oncogene, 22, 8590, 10.1038/sj.onc.1207102
Adams, 2003, Ways of dying: multiple pathways to apoptosis, Genes Dev, 17, 2481, 10.1101/gad.1126903
Kim, 2002, Current status of the molecular mechanisms of anticancer drug-induced apoptosis. The contribution of molecular-level analysis to cancer chemotherapy, Cancer Chemother Pharmacol, 50, 343, 10.1007/s00280-002-0522-7
Makin, 2002, Targeting apoptosis in cancer chemotherapy, Expert Opin Ther Targets, 6, 73, 10.1517/14728222.6.1.73
Klasa, 2002, Oblimersen Bcl-2 antisense: facilitating apoptosis in anticancer treatment, Antisense Nucleic Acid Drug Dev, 12, 193, 10.1089/108729002760220798
Khodadoust, 2001, Bcl-2 Antisense oligodeoxynucleotide (Genasense) enhances gemtuzumab ozogamicin (Mylotarg)-induced cytotoxicity in acute myeloid leukemia, Blood, 98, 102a
Sievers, 2001, Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse, J Clin Oncol, 19, 3244, 10.1200/JCO.2001.19.13.3244
Bickel, 1977
Garrido, 2001, Blasts from elderly acute myeloid leukemia patients are characterized by low levels of culture- and drug-induced apoptosis, Leuk Res, 25, 23, 10.1016/S0145-2126(00)00083-7
Vey, 1999, Effect of complete remission on survival in patients with acute myelogenous leukemia receiving first salvage therapy, Blood, 93, 3149, 10.1182/blood.V93.9.3149
Marcucci, 2003, Phase 1 and pharmacodynamic studies of G3139, a Bcl-2 antisense oligonucleotide, in combination with chemotherapy in refractory or relapsed acute leukemia, Blood, 101, 425, 10.1182/blood-2002-06-1899
Marcucci, 2003, Pharmacologic and biologic assessment of Genasense (GNS, oblimersen sodium), a pro-apoptotic to Bcl-2 oligonucleotide, in combination with daunorubicin and cytarabine: a Phase I study in previously untreated elderly acute myeloid leukemia (AML), Blood, 102, 874a
Marcucci, 2005, Phase I study of oblimersen sodium, an antisense to Bcl-2, in untreated older patients with acute myeloid leukemia: pharmacokinetics, pharmacodynamics and clinical activity, J Clin Oncol, 23, 3404, 10.1200/JCO.2005.09.118
Kirkwood, 2005, Long-term survival results of a randomized multinational Phase 3 trial of dacarbazine (DTIC) with or without Bcl-2 antisense (oblimersen sodium) in patients (pts) with advanced malignant melanoma (MM), J Clin Oncol, 23, 711s, 10.1200/jco.2005.23.16_suppl.7506
Rai, 2004, Phase 3 randomized trial of fludarabine/cyclophosphamide chemotherapy with or without oblimersen sodium (Bcl-2 antisense; genasense; G3139) for patients with relapsed or refractory chronic lymphocytic leukemia (CLL), Blood, 104, 100a, 10.1182/blood.V104.11.338.338
Leith, 1997, Acute myeloid leukemia in the elderly: assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A southwest oncology group study, Blood, 89, 3323, 10.1182/blood.V89.9.3323