Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial

The Lancet - Tập 359 - Trang 1541-1549 - 2002
Stephen B Hanauer1, Brian G Feagan2, Gary R Lichtenstein3, Lloyd F Mayer4, S Schreiber5, Jean Frederic Colombel6, Daniel Rachmilewitz7, Douglas C Wolf8, Allan Olson9, Weihang Bao9, Paul Rutgeerts10
1Department of Gastroenterology and Nutrition, University of Chicago Medical Center, Chicago, IL, USA
2London Health Sciences Center, University of Western Ontario, London, Ontario, Canada
3Department of Gastroenterology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
4Department of Clinical Immunology, Mount Sinai Medical Center, New York, NY, USA
5Klinikum der Christian-Albrechs-Universität, Kiel, Germany
6Hôpital Claude Huriez, CHU de Lille, Lille, France
7Division of Medicine, Tel-Aviv Sourasky Medical Center, Tel Aviv, Israel
8Atlanta Gastroenterology Associates, Atlanta, GA, USA
9Centocor, Malvern, PA, USA
10Afdeling Gastroenterologie, Universitair Ziekenhuis Gasthuisberg, Leuven, Belgium

Tài liệu tham khảo

Faubion, 2001, The natural history of corticosteroid therapy for inflammatory bowel disease: a population-based study, Gastroenterology, 121, 255, 10.1053/gast.2001.26279 Munkholm, 1994, Frequency of glucocorticoid resistance and dependency in Crohn's disease, Gut, 35, 360, 10.1136/gut.35.3.360 Steinhart, 2000, Maintenance therapy in Crohn's disease, Can J Gastroenterol Update Liver Inflammatory Bowel Dis (ULIBD), 14, 23 Sandborn, 2000, Azathioprine or 6-mercaptopurine for inducing remission of Crohn's disease, Cochrane Database Syst Rev, 2, CD000545 Feagan, 1995, Methotrexate for the treatment of Crohn's disease, N Engl J Med, 332, 292, 10.1056/NEJM199502023320503 Kindler, 1989, The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection, Cell, 56, 731, 10.1016/0092-8674(89)90676-4 Braegger, 1992, Tumour necrosis factor alpha in stool as a marker of intestinal inflammation, Lancet, 339, 89, 10.1016/0140-6736(92)90999-J Beese, 1994, Tumor necrosis factor alpha-producing cells in the intestinal mucosa of children with inflammatory bowel disease, Gastroenterology, 106, 1455, 10.1016/0016-5085(94)90398-0 MacDonald, 1990, Tumor necrosis factor-alpha and interferon gamma production measured at the single cell level in normal and inflamed human intestine, Clin Exp Immunol, 81, 301, 10.1111/j.1365-2249.1990.tb03334.x Schreiber, 1999, Tumour necrosis factor α and interleukin 1 β in relapse of Crohn's disease, Lancet, 359, 459, 10.1016/S0140-6736(98)03339-X Knight, 1993, Construction and initial characterization of a mouse-human chimeric anti-TNF antibody, Mol Immunol, 30, 1443, 10.1016/0161-5890(93)90106-L Targan, 1997, A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease, N Engl J Med, 337, 1029, 10.1056/NEJM199710093371502 Cohen, 2000, Infliximab in Crohn's disease: first anniversary clinical experience, Am J Gastroenterol, 95, 3469, 10.1111/j.1572-0241.2000.03363.x Ricart, 2001, Infliximab for Crohn's disease in clinical practice at the Mayo Clinic: the first 100 patients, Am J Gastroenterol, 96, 722, 10.1111/j.1572-0241.2001.03612.x Nikolaus, 2000, Mechanisms in failure of infliximab for Crohn's disease, Lancet, 356, 1475, 10.1016/S0140-6736(00)02871-3 Rutgeerts, 1999, Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease, Gastroenterology, 117, 761, 10.1016/S0016-5085(99)70332-X Best, 1976, Development of a Crohn's Disease Activity Index: National Cooperative Crohn's Disease Study, Gastroenterology, 70, 439, 10.1016/S0016-5085(76)80163-1 Irvine, 1994, Quality of life: a valid and reliable measure of therapeutic efficacy in the treatment of inflammatory bowel disease, Gastroenterology, 106, 287, 10.1016/0016-5085(94)90585-1 Keane, 2001, Tuberculosis associated with infliximab, a TNF-alpha neutralizing agent, N Engl J Med, 345, 1098, 10.1056/NEJMoa011110 Baker, 2001, Tuberculosis occurring in patients receiving the anti-TNF agent infliximab, Arthritis Rheum, 44, S105 Toy, 2000, Complete bowel obstruction following initial response to infliximab therapy for Crohn's disease: a series of a newly described complication, Gastroenterology, 118, A569, 10.1016/S0016-5085(00)84412-1 Maini, 1998, Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis, Arthritis Rheum, 41, 1552, 10.1002/1529-0131(199809)41:9<1552::AID-ART5>3.0.CO;2-W Schaible, 2000, Long term safety of infliximab, Can J Gastroenterol Update Liver Inflammatory Bowel Dis (ULIBD), 14, 29 Sachmechian, 2001, Malignancy following Remicade therapy: incidence and characteristics, Gastroenterology, 120, A619, 10.1016/S0016-5085(08)83081-8 Bernstein, 2001, Cancer risk in patients with inflammatory bowel disease, Cancer, 91, 854, 10.1002/1097-0142(20010215)91:4<854::AID-CNCR1073>3.0.CO;2-Z Greenstein, 1991, Lymphoma in inflammatory bowel disease, Cancer, 69, 1119, 10.1002/cncr.2820690510 Ekborn, 1990, Extracolonic malignancies in inflammatory bowel disease, Cancer, 67, 2015