Gene amplification in human neuroblastomas: Basic mechanisms and clinical implications

Brodeur, 1975, Specific chromosomal aberration in human neuroblastoma, Am J Hum Genet, 27, 20A Brodeur, 1977, Chromosomal aberrations in human neuroblastomas, Cancer, 40, 2256, 10.1002/1097-0142(197711)40:5<2256::AID-CNCR2820400536>3.0.CO;2-1 Brodeur, 1981, Cytogenetic features of human neuroblastomas and cell lines, Cancer Res, 41, 4678 Brodeur, 1982, Statistical analysis of cytogenetic abnormalities in human cancer cells, Cancer Genet Cytogenet, 7, 137, 10.1016/0165-4608(82)90010-3 Biedler, 1980, Human neuroblastoma cytogenetics: Search for significance of homogeneously staining regions and double minute chromosomes, 81 Gilbert, 1984, Human neuroblastomas and abnormalities of chromosomes 1 and 17, Cancer Res, 44, 5444 Cox, 1965, Minute chromatin bodies in malignant tumours of childhood, Lancet, ii, 55, 10.1016/S0140-6736(65)90131-5 Biedler, 1976, Metaphase chromosome anomaly: Association with drug resistance and cell-specific products, Science, 191, 185, 10.1126/science.942798 Biedler, 1976, A novel chromosome abnormality in human neuroblastoma and antifolate-resistant Chinese hamster cell lines in culture, J Natl Cancer Inst, 57, 683, 10.1093/jnci/57.3.683 1982 Cowell, 1982, Double minutes and homogeneously staining regions: Gene amplification in mammalian cells, Ann Rev Genet, 16, 21, 10.1146/annurev.ge.16.120182.000321 Schimke, 1984, Gene amplification in cultured animal cells, Cell, 37, 705, 10.1016/0092-8674(84)90406-9 Schwab, 1983, Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour, Nature, 305, 245, 10.1038/305245a0 Schwab, 1984, Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc, Nature, 308, 288, 10.1038/308288a0 Kohl, 1983, Transposition and amplification of oncogene related sequences in human neuroblastomas, Cell, 35, 359, 10.1016/0092-8674(83)90169-1 Montgomery, 1983, Specific DNA sequence amplification in human neuroblastoma cells, 80, 5724 Kanda, 1983, Isolation of amplified DNA sequences from IMR-32 human neuroblastoma cells: Facilitation by fluorescence-activated flow sorting of metaphase chromosomes, 80, 4069 Bahr, 1983, Homogeneously staining regions and double minutes in a human cell line: Chromatin organization and DNA content, J Natl Cancer Inst, 71, 657 Kaufman, 1979, Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes, 76, 5669 Milbrandt, 1981, Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene, 78, 6043 Montoya-Zavala, 1985, Similar 150-kilobase DNA sequences are amplified in independently derived methotrexate-resistant Chinese hamster cells, Mol Cell Biol, 5, 619, 10.1128/MCB.5.4.619 Roninson, 1983, Detection and mapping of homologous, repeated and amplified DNA sequences by DNA renaturation in agarose gels, Nucl Acids Res, 11, 5413, 10.1093/nar/11.16.5413 Kinzler, 1985, Amplification units containing human N-myc and C-myc genes Beverley, 1984, Unstable DNA amplifications in methotrexate-resistant Leishmania consist of extrachromosomal circles which relocalize during stabilization, Cell, 38, 431, 10.1016/0092-8674(84)90498-7 Roberts, 1983, A structure for amplified DNA, Cell, 33, 53, 10.1016/0092-8674(83)90334-3 Ardeshir, 1983, Structure of amplified DNA in different Syrian hamster cell lines resistant to N-(phosphonacetyl)-L-aspartate, Mol Cell Biol, 3, 2076, 10.1128/MCB.3.11.2076 Shiloh, 1985, Differential amplification, assembly and relocation of multiple DNA sequences in human neuroblastomas and neuroblastoma cell lines, 82, 3761 Carle, 1984, Separation of chromosomal DNA molecules from yeast by orthogonal-field-alternation gel electrophoresis, Nucl Acids Res, 12, 5647, 10.1093/nar/12.14.5647 Carle, 1985, An electrophoretic karyotype for yeast, 82, 3756 Balaban-Malenbaum, 1977, Double minute chromosomes and the homogeneously staining regions in chromosomes of a human neuroblastoma cell line, Science, 198, 739, 10.1126/science.71759 Balaban-Malenbaum, 1980, Relationship between homogeneously staining regions and double minute chromosomes in human neuroblastoma cell lines, 97 Balaban, 1982, Homogeneously staining regions in direct preparations from human neuroblastomas, Cancer Res, 42, 1838 Balaban-Malenbaum, 1980, The proposed origin of double minutes from homogeneously staining region (HSR)-marker chromosomes in human neuroblastoma hybrid cell lines, Cancer Genet Cytogenet, 2, 339, 10.1016/0165-4608(80)90065-5 Trent, 1984, Evidence for selection of homogeneously staining regions in a human melanoma cell line, Cancer Res, 44, 233 Emanuel, 1985, N-myc amplification in multiple HSRs in two human neuroblastomas, 82, 3736 Seeger, 1977, Morphology, growth, chromosomal pattern, and fibrinolytic activity of two new human neuroblastoma cell lines, Cancer Res, 37, 1364 LeBeau, 1984, Heritable fragile sites in cancer, Nature, 308, 607, 10.1038/308607a0 Hecht, 1984, Fragile sites and cancer breakpoints, Cancer Genet Cytogenet, 12, 179, 10.1016/0165-4608(84)90132-8 Yunis, 1984, Constitutive fragile sites and cancer, Science, 226, 1199, 10.1126/science.6239375 Brodeur, 1986, Molecular correlates of cytogenetic abnormalities in human cancer cells: Implications for oncogene activation Brodeur, 1984, Amplification of N-myc in untreated human neuroblastoma correlates with advanced disease stage, Science, 224, 1121, 10.1126/science.6719137 Seeger, 1985, Association of multiple copies of the N-myconcogene with rapid progression of neuroblastomas, N Engl J Med, 10.1056/NEJM198510313131802 Lee, 1984, Expression and amplification of the N-myc gene in primary retinoblastoma, Nature, 309, 458, 10.1038/309458a0 Schwenn, 1985, N-myc amplification and expression in a malignant schwannoma from a patient with neurofibromatosis Collins, 1982, Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line, Nature, 298, 679, 10.1038/298679a0 Dalla Favera, 1982, Onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient, Nature, 299, 61, 10.1038/299061a0 Nowell, 1983, Association of amplified oncogene c-myc with an abnormally banded chromosome 8 in a human leukaemia cell line, Nature, 306, 494, 10.1038/306494a0 Alitalo, 1983, Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in colon carcinoma, 80, 1707 Little, 1983, Amplification and expression of the c-myc oncogene in human lung cancer cell lines, Nature, 306, 194, 10.1038/306194a0 Saksela, 1985, Amplification of the c-myc oncogene in a subpopulation of human small cell lung cancer, Cancer Res, 45, 1823 Kozbor, 1984, Amplification of the c-myc oncogene in one of five human breast carcinoma cell lines, Cancer Res, 44, 438 Shibuya, 1985, Amplification and expression of a cellular oncogene (c-myc) in human gastric adenocarcinoma cells, Mol Cell Biol, 5, 414, 10.1128/MCB.5.2.414 Trent, 1985, Evidence for rearrangement and amplification of the c-myc cellular oncogene in a human glioblastoma Pelicci, 1984, Amplification of the c-myb oncogene in a case of human acute myelogenous leukemia, Science, 224, 1117, 10.1126/science.6585957 Alitalo, 1984, Aberrant expression of an amplified c-myb oncogene in two cell lines from a colon carcinoma, 81, 4534 Collins, 1983, Rearrangement and amplification of c-abl sequences in the human chronic myelogenous leukemia cell line K-562, 80, 4813 Selden, 1983, Amplified C-lambda and c-abl genes are on the same marker chromosome in K562 leukemia cells, 80, 7289 Marlino, 1984, Amplification and enhanced expression of the epidermal growth factor receptor gene in A431 human carcinoma cells, Science, 224, 417, 10.1126/science.6200934 Lin, 1984, Expression cloning of human EGF receptor complementary DNA: Gene amplification and three related messenger RNA products in A431 cells, Science, 224, 843, 10.1126/science.6326261 Ullrich, 1984, Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells, Nature, 309, 418, 10.1038/309418a0 Libermann, 1985, Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin, Nature, 313, 144, 10.1038/313144a0 Graham, 1985, Varying degrees of amplification of N-ras oncogene in the breast cancer cell line MCF-7, Cancer Res, 45, 2201 Filmus, 1985, Stability of e-K-ras amplification during progression in a patient with adenocarcinoma of the ovary, Cancer Res, 45, 4468 King, 1985, Amplification of a novel v-erbB-related gene in a human mammary carcinoma, Science, 229, 974, 10.1126/science.2992089 Schechter, 1985, The neu gene: An erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor, Science, 229, 976, 10.1126/science.2992090