Meta-analysis identifies six new susceptibility loci for atrial fibrillation

Nature Genetics - Tập 44 Số 6 - Trang 670-675 - 2012
Patrick T. Ellinor1, Kathryn L. Lunetta2, Christine M. Albert3, Nicole L. Glazer4, Marylyn D. Ritchie5, Albert Hofman6, Dan E. Arking7, Martina Müller‐Nurasyid8, Bouwe P. Krijthe9, Steven A. Lubitz1, Joshua C. Bis4, Mina K. Chung10, Marcus Dörr11, Kouichi Ozaki12, Jason D. Roberts13, J. G. Smith14, Arne Pfeufer15, Moritz F. Sinner16, Kirsten Ohm Kyvik17, Jingzhong Ding18, Nicholas L. Smith4, Jonathan Smith10, Michiel Rienstra1, Kenneth Rice19, David R. Van Wagoner10, Jared W. Magnani16, Reza Wakili8, Sebastian Clauß8, Jerome I. Rotter20, Gerhard Steinbeck8, Lenore J. Launer21, R. W. Davies22, Matthew Borkovich13, Tamara B. Harris21, Honghuang Lin23, Uwe Völker24, Henry Völzke25, David J. Milan26, Eric Boerwinkle27, Lin Y. Chen28, Elsayed Z. Soliman29, Benjamin F. Voight30, Li Guo4, Aravinda Chakravarti7, Michiaki Kubo31, Usha B. Tedrow32, Roberto Jorge da Silva Franco33, Paul M. Ridker32, David Conen34, Tatsuhiko Tsunoda35, Tetsushi Furukawa36, Nona Sotoodehnia4, Simiao Xu2, Naoyuki Kamatani37, Daniel Lévy16, Yusuke Nakamura38, Babar Parvez39, Saagar Mahida1, Karen L. Furie3, Nathan A. Bihlmeyer3, Raafia Muhammad39, Bruce M. Psaty4, Thomas Meitinger15, Siegfried Perz40, H‐Erich Wichmann41, Jacqueline R. Center42, W.H. Linda Kao43, Sekar Kathiresan30, Dan M. Roden39, André G. Uitterlinden42, Fernando Rivadeneira42, Barbara McKnight19, Marketa Sjögren44, Anne B. Newman45, Yongmei Liu46, Michael H. Gollob13, Olle Melander44, Toshihiro Tanaka12, Bruno H. Stricker42, Stephan B. Felix11, Álvaro Alonso47, Dawood Darbar39, John Barnard48, Daniel I. Chasman33, Susan R. Heckbert49, Emelia J. Benjamin23, Vilmundur Guðnason50, Stefan Kääb8
1Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts, USA
2Department of Biostatistics, School of Public Health, Boston University, Boston, Massachusetts, USA
3Harvard Medical School Boston Massachusetts USA
4Department of Medicine, Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA
5Center for Systems Genomics, Pennsylvania State University, University Park, Pennsylvania, USA
6Icelandic Heart Association Research Institute, Kopavogur, Iceland
7McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
8Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-University, Munich, Germany
9Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
10Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio, USA
11Department of Internal Medicine B, Ernst Moritz Arndt University Greifswald, Greifswald, Germany
12Laboratory for Cardiovascular Diseases, RIKEN Center for Genomic Medicine, Kanagawa, Japan
13Arrhythmia Research Laboratory, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
14Department of Cardiology, Lund University, Lund, Sweden
15Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg Germany
16National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, USA
17Department of Biostatistical Sciences, Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
18Sticht Center on Aging, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA
19Department of Biostatistics, University of Washington, Seattle, Washington, USA.
20Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA
21Laboratory of Epidemiology, Demography, and Biometry, Intramural Research Program, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA
22Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
23Department of Medicine, Cardiology Section, Boston University School of Medicine, Boston, Massachusetts, USA
24Interfaculty Institute for Genetics and Functional Genomics, Ernst Moritz Arndt University Greifswald, Greifswald, Germany
25Institute for Community Medicine, Ernst Moritz Arndt University Greifswald, Greifswald, Germany
26Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, Massachusetts, USA.
27Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, USA
28Cardiovascular Division, Department of Medicine, Cardiac Arrhythmia Center, University of Minnesota Medical School, Minneapolis, Minnesota, USA
29Epidemiological Cardiology Research Center (EPICARE), Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
30Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA;
31Laboratory for Genotyping Development, RIKEN Center for Genomic Medicine, Kanagawa, Japan
32Division of Cardiology, Brigham and Women’s Hospital, Boston, Massachusetts, USA
33Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA
34Department of Medicine, University Hospital, Basel, Switzerland
35Laboratory for Medical Informatics, RIKEN Center for Genomic Medicine, Kanagawa, Japan
36Department of Bio-informational Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan
37Laboratory for Statistical Analysis, RIKEN Center for Genomic Medicine, Kanagawa, Japan
38Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan
39Department of Medicine, Vanderbilt University School of Medicine Nashville, Tennessee, USA
40Institute for Biological and Medical Imaging, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany
41Chair of Epidemiology, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany
42Netherlands Consortium for Healthy Aging (NCHA), The Netherlands
43Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland, USA
44Department of Clinical Sciences, Lund University, Malmo, Sweden
45Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
46Department of Epidemiology & Prevention, Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA
47Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
48Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA
49Group Health Research Institute, Group Health Cooperative, Seattle, Washington, USA
50Faculty of Medicine, University of Iceland, Reykjavik, Iceland

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Nature Genetics

Tập 44 Số 6

670-675

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