Identification and Characterization of Genes Susceptible to Transcriptional Cross-Talk between the Hypoxia and Dioxin Signaling Cascades
Tóm tắt
Từ khóa
Tài liệu tham khảo
Gu, Y-Z., Hogenesch, J., and Bradfield, C. (2000)The PAS Superfamily: Sensors of Environmental and Developmental Signals. pp 519−561, Academic Press, New York.
Schmidt J. V., 1993, J. Biol. Chem., 268
Semenza, G. L., Agani, F., Booth, G., Forsythe, J., Iyer, N., Jiang, B. H., Leung, S., Roe, R., Wiener, C., and Yu, A. (1997) Structural and functional analysis of hypoxia-inducible factor 1.Kidney Int.51, 553−555.
Reyes H., 1992, Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor. Science 256, 1193−1195
Wang G. L., 1995, Proc. Natl. Acad. Sci. U.S.A. 92
Bradfield C. A., 1988, A competitive binding assay for 2,3,7,8-tetrachlorodibenzo-p-dioxin and related ligands of the Ah receptor. Mol. Pharmacol. 34, 682−688
Ma Q., 1997, J. Biol. Chem., 272
Whitlock J. P., 1989, Induction of hepatic cytochrome P450 gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Mol. Biol. Med. 6, 169−178
Wang G. L., 1993, J. Biol. Chem., 268
Bruick R. K., 2001, A conserved family of prolyl-4-hydroxylases that modify HIF. Science 294, 1337−1340
Brunelle J. K., 2005, Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation. Cell Metab. 1, 409−414
Guzy R. D., 2005, Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing. Cell Metab. 1, 401−408
Mansfield K. D., 2005, Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation. Cell. Metab. 1, 393−399
Mole D. R., 2001, IUBMB Life., 52, 47
Minchenko A., 1994, Cell. Mol. Biol. Res., 40, 39
Chan W. K., 1999, J. Biol. Chem., 274
Gassmann M., 1997, Oxygen- and dioxin-regulated gene expression in mouse hepatoma cells. Kidney Int. 51, 567−574
Gradin K., 1996, Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor. Mol. Cell. Biol. 16, 5221−5231
Nie M., 2001, Environ. Toxicol. Pharmacol., 10, 27
Pollenz, R. S., Davarinos, N. A., and Shearer, T. P. (1999) Analysis of aryl hydrocarbon receptor-mediated signaling during physiological hypoxia reveals lack of competition for the aryl hydrocarbon nuclear translocator transcription factor.Mol. Pharmacol.56, 1127−1137.
Ihaka R., 1996, J. Comp. Graph. Stats., 5
Wu Z., 2004, A model based background adjustment for oligonucleotide expression arrays
Vengellur A., 2003, Gene expression profiling of the hypoxia signaling pathway in hypoxia inducible factor 1 null mouse embryonic fibroblasts. Gene Expression 11, 181−197
Quandt K., 1995, MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res. 23, 4878−4884
Sun Y. V., 2004, Comparative analysis of dioxin response elements in human, mouse and rat genomic sequences. Nucleic Acids Res. 32, 4512−4523
Burgoon L. D., 2006, dbZach: A MIAME-compliant toxicogenomic supportive relational database. Toxicol. Sci. 90, 558−568
Wingender E., 2004, Silico Biol., 4, 61
Herrero J., 2003, GEPAS: a web-based resource for microarray gene expression data analysis. Nucleic Acids Res. 31, 3461−3467
Wang L., 2004, Transcriptional crosstalk between nuclear receptors and cytokine signal transduction pathways in immunity. Cell. Mol. Immunol. 1, 416−24
Chang H., 2003, J. Biomed. Sci., 10
Ebert B. L., 1995, J. Biol. Chem., 270
Yan S-F, 1999, J. Biol. Chem., 274
Fradette C., 2004, Effect of hypoxia on cytochrome P450 activity and expression. Curr. Drug Metab. 5, 257−71
Harstad E. B., 2006, Liver deformation in Ahr-null mice: evidence for aberrant hepatic perfusion in early development. Mol. Pharmacol. 69, 1534−1541
Lund A. K., 2003, Cardiac hypertrophy in aryl hydrocarbon receptor null mice is correlated with elevated angiotensin II, endothelin-1, and mean arterial blood pressure. Toxicol. Appl. Pharmacol. 193, 177−187
Lund A. K., 2006, Characterizing the role of endothelin-1 in the progression of cardiac hypertrophy in aryl hydrocarbon receptor (AhR) null mice. Toxicol. Appl. Pharmacol. 212, 127−135
Thackaberry E. A., 2002, Aryl hydrocarbon receptor null mice develop cardiac hypertrophy and increased hypoxia-inducible factor-1alpha in the absence of cardiac hypoxia. Cardiovasc. Toxicol. 2, 263−274
Abbreviations AHR, aryl hydrocarbon receptor