Negative life events and stress sensitivity in youth’s daily life: an ecological momentary assessment study

Social psychiatry - Tập 57 - Trang 1641-1657 - 2022
Christian Rauschenberg1,2, Julia C. C. Schulte-Strathaus1,2, Jim van Os3,4, Matthieu Goedhart5,6, Jan N. M. Schieveld7, Ulrich Reininghaus2,8,9
1Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands
2Department of Public Mental Health, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
3Department of Psychiatry, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht, The Netherlands
4Psychosis Studies Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK
5Tilburg School of Humanities, Tilburg University, Tilburg, The Netherlands
6Mutsaers Foundation and Educational Institute Wijnberg, Venlo, The Netherlands
7Division of Child and Adolescent Psychiatry, Department of Psychiatry and Psychology, Maastricht University Medical Centre (MUMC+), Maastricht, The Netherlands
8ESRC Centre for Society and Mental Health, King’s College London, London, UK
9Centre for Epidemiology and Public Health, Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK

Tóm tắt

Negative life events (LEs) are associated with mental health problems in youth. However, little is known about underlying mechanisms. The aim of the study was to investigate whether exposure to LEs modifies stress sensitivity in youth’s daily life. Ecological Momentary Assessment (EMA) was used to assess stress sensitivity (i.e., association of momentary stress with (i) negative affect and (ii) psychotic experiences) in 99 adolescents and young adults (42 service users, 17 siblings, and 40 controls; Mage 15 years). Before EMA, exposure to LEs (e.g., intrusive threats, experience of loss, serious illness) was assessed. Lifetime as well as previous-year exposure to LEs modified stress sensitivity in service users: they experienced more intense negative affect and psychotic experiences in response to stress when high vs. low exposure levels were compared. In contrast, controls showed no differences in stress sensitivity by exposure levels. Looking at specific types of LEs, controls showed less intense negative affect in response to stress when high vs. low exposure levels to threatening events during the last year, but not lifetime exposure, were compared. In siblings, no evidence was found that LEs modified stress sensitivity. Stress sensitivity may constitute a putative risk mechanism linking LEs and mental health in help-seeking youth, while unfavourable effects of LEs on stress sensitivity may attenuate over time or do not occur in controls and siblings. Targeting individuals’ sensitivity to stress in daily life using novel digital interventions may be a promising approach towards improving youth mental health.

Tài liệu tham khảo

McGorry PD et al (2006) Clinical staging of psychiatric disorders: a heuristic framework for choosing earlier, safer and more effective interventions. Aust N Z J Psychiatry 40(8):616–622 Kessler RC et al (2005) Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 62(6):593–602 Malla A et al (2016) From early intervention in psychosis to youth mental health reform: a review of the evolution and transformation of mental health services for young people. Soc Psychiatry Psychiatr Epidemiol 51(3):319–326 McGorry PD, van Os J (2013) Redeeming diagnosis in psychiatry: timing versus specificity. Lancet 381(9863):343–345 van Os J, Reininghaus U (2016) Psychosis as a transdiagnostic and extended phenotype in the general population. World Psychiatry 15(2):118–124 Beards S et al (2013) Life events and psychosis: a review and meta-analysis. Schizophr Bull 39(4):740–747 Jenness JL et al (2019) Dynamic associations between stressful life events and adolescent internalizing psychopathology in a multiwave longitudinal study. J Abnorm Psychol 128(6):596 March-Llanes J et al (2017) Stressful life events during adolescence and risk for externalizing and internalizing psychopathology: a meta-analysis. Eur Child Adolesc Psychiatry 26(12):1409–1422 Boardman JD, Alexander KB, Stallings MC (2011) Stressful life events and depression among adolescent twin pairs. Biodemography Soc Biol 57(1):53–66 Pries LK et al (2020) Association of recent stressful life events with mental and physical health in the context of genomic and exposomic liability for schizophrenia. JAMA Psychiat 77(12):1296–1304 McLaughlin KA et al (2012) Childhood adversities and first onset of psychiatric disorders in a national sample of US adolescents. Arch Gen Psychiatry 69(11):1151–1160 Humphreys KL et al (2019) Stressful life events, ADHD symptoms, and brain structure in early adolescence. J Abnorm Child Psychol 47(3):421–432 Liu RT, Miller I (2014) Life events and suicidal ideation and behavior: a systematic review. Clin Psychol Rev 34(3):181–192 Beards S et al (2020) Threatening life events and difficulties and psychotic disorder. Schizophr Bull 46(4):814–822 Ayesa-Arriola R et al (2020) The synergetic effect of childhood trauma and recent stressful events in psychosis: associated neurocognitive dysfunction. Acta Psychiatr Scand 141(1):43–51 Elmore AL, Crouch E (2020) The association of adverse childhood experiences with anxiety and depression for children and youth, 8 to 17 years of age. Acad Pediatr 20(5):600–608 Schwager S, Rothermund K (2013) Counter-regulation triggered by emotions: Positive/negative affective states elicit opposite valence biases in affective processing. Cogn Emot 27(5):839–855 Collip D, Myin-Germeys I, Van Os J (2008) Does the concept of “sensitization” provide a plausible mechanism for the putative link between the environment and schizophrenia? Schizophr Bull 34(2):220–225 Howes OD, Murray RM (2014) Schizophrenia: an integrated sociodevelopmental-cognitive model. Lancet 383(9929):1677–1687 Myin-Germeys I et al (2018) Experience sampling methodology in mental health research: new insights and technical developments. World Psychiatry 17(2):123–132 Rauschenberg C et al (2017) Stress sensitivity as a putative mechanism linking childhood trauma and psychopathology in youth’s daily life. Acta Psychiatr Scand 136(4):373–388 Rauschenberg C et al (2021) Bullying victimization and stress sensitivity in help-seeking youth: findings from an experience sampling study. Eur Child Adolesc Psychiatry 30(4):591–605 Brugha T et al (1985) The List of Threatening Experiences: a subset of 12 life event categories with considerable long-term contextual threat. Psychol Med 15(1):189–194 Brugha T, Cragg D (1990) The List of Threatening Experiences: the reliability and validity of a brief life events questionnaire. Acta Psychiatr Scand 82(1):77–81 Beck A, Steer R, Brown G (1996) Manual for the Beck depression inventory-II (BDI-II), vol 10. Pearson, London, UK Osman A et al (2004) Reliability and validity of the Beck depression inventory–II with adolescent psychiatric inpatients. Psychol Assess 16(2):120 Osman A et al (2008) Psychometric properties of the Beck Depression Inventory-II in nonclinical adolescent samples. J Clin Psychol 64(1):83–102 van der Ploeg H (1982) De zelf-beoordelings vragenlijst (STAI-DY). Tijdschr Psychiatr 24:576–588 Spielberger CD, Gorsuch RL (1983) State-trait anxiety inventory for adults: Manual and sample: manual, instrument and scoring guide. Consulting Psychologists Press Julian LJ (2011) Measures of anxiety: state-trait anxiety inventory (STAI), Beck anxiety inventory (BAI), and Hospital anxiety and Depression scale-anxiety (HADS-A). Arthritis Care Res 63(S11):S467–S472 Konings M et al (2006) Validity and reliability of the CAPE: a self-report instrument for the measurement of psychotic experiences in the general population. Acta Psychiatr Scand 114(1):55–61 Reininghaus U et al (2016) Psychological processes underlying the association between childhood trauma and psychosis in daily life: an experience sampling study. Psychol Med 46(13):2799–2813 Matsunaga M (2007) Familywise error in multiple comparisons: disentangling a knot through a critique of O’Keefe’s arguments against alpha adjustment. Commun Methods Meas 1(4):243–265 Reuben A et al (2016) Lest we forget: comparing retrospective and prospective assessments of adverse childhood experiences in the prediction of adult health. J Child Psychol Psychiatry 57(10):1103–1112 Gayer-Anderson C et al (2020) A comparison between self-report and interviewer-rated retrospective reports of childhood abuse among individuals with first-episode psychosis and population-based controls. J Psychiatr Res 123:145–150 Vaessen T et al (2018) Overall cortisol, diurnal slope, and stress reactivity in psychosis: An experience sampling approach. Psychoneuroendocrinology 96:61–68 Onnela J-P, Rauch SL (2016) Harnessing smartphone-based digital phenotyping to enhance behavioral and mental health. Neuropsychopharmacology 41(7):1691–1696 McLaughlin KA (2019) Early life stress and psychopathology. In: The Oxford handbook of stress and mental health. Oxford University Press, Oxford, UK McShane BB et al (2019) Abandon statistical significance. Am Stat 73(sup1):235–245 Ioannidis JPA (2018) The proposal to lower P value thresholds to .005. JAMA 319(14):1429–1430 Hurlbert SH, Levine RA, Utts J (2019) Coup de Grâce for a tough old bull: “statistically significant” expires. Am Stat 73(sup1):352–357 Klippel A, Schick A, MyinGermeys I, Rauschenberg C, Vaessen T, Reininghaus U (2021) Modelling the temporal interplay between stress and affective disturbances in pathways to psychosis: an experience sampling study. Psychol Med 1–10. https://doi.org/10.1017/S0033291720004894 LeMoult J et al (2020) Meta-analysis: exposure to early life stress and risk for depression in childhood and adolescence. J Am Acad Child Adolesc Psychiatry 59(7):842–855 Lardinois M et al (2011) Childhood trauma and increased stress sensitivity in psychosis. Acta Psychiatr Scand 123(1):28–35 Askeland KG et al (2020) Life events and adolescent depressive symptoms: Protective factors associated with resilience. PLoS ONE 15(6):e0234109 Crush E et al (2018) Protective factors for psychotic symptoms among poly-victimized children. Schizophr Bull 44(3):691–700 Fritz J et al (2018) A systematic review of amenable resilience factors that moderate and/or mediate the relationship between childhood adversity and mental health in young people. Front Psych 9:230 Kuranova A et al (2020) Don’t worry, be happy: protective factors to buffer against distress associated with psychotic experiences. Schizophr Res 223:79–86 Perchtold CM et al (2019) Humorous cognitive reappraisal: More benign humour and less" dark" humour is affiliated with more adaptive cognitive reappraisal strategies. PLoS ONE 14(1):e0211618 Kashdan TB, Rottenberg J (2010) Psychological flexibility as a fundamental aspect of health. Clin Psychol Rev 30(7):865–878 Fonseca S et al (2020) The buffer role of psychological flexibility against the impact of major life events on depression symptoms. Clin Psychol 24(1):82–90 Lazarus RS, Folkman S (1984) Coping and adaptation. In: The handbook of behavioral medicine. Wiley, New Jersey, USA Vassos E, Sham P, Kempton M, Trotta A, Stilo SA, Gayer-Anderson C, Di Forti M, Lewis CM, Murray RM, Morgan C (2020) The Maudsley environmental risk score for psychosis. Psychol Med 50(13):2213–2220. https://doi.org/10.1017/S0033291719002319 Kotov R et al (2017) The Hierarchical Taxonomy of Psychopathology (HiTOP): a dimensional alternative to traditional nosologies. J Abnorm Psychol 126(4):454 Rauschenberg C, Boecking B, Paetzold I, Schruers K, Schick A, van Amelsvoort T, Reininghaus U (2021) A compassion-focused ecological momentary intervention for enhancing resilience in help-seeking youth: uncontrolled pilot study. JMIR Mental Health 8(8): Myin-Germeys I et al (2016) Ecological momentary interventions in psychiatry. Curr Opin Psychiatry 29(4):258–263 Schick A, Paetzold I, Rauschenberg C, Hirjak D, Banaschewski T, Meyer-Lindenberg A, Boehnke JR, Benjamin B, Reininghaus U (2021) Effects of a novel, transdiagnostic, hybrid ecological momentary intervention for improving resilience in youth (EMIcompass): protocol for an exploratory randomized controlled trial. JMIR Res Protoc 10(12): https://doi.org/10.2196/27462