An autocrine role for endothelin-1 in the regulation of proximal tubule NHE3

Preisig, 1987, Role of the Na/H antiporter in rat proximal tubule bicarbonate absorption, J Clin Invest, 80, 970, 10.1172/JCI113190 Amemiya, 1995, Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb, Kidney Int, 48, 1206, 10.1038/ki.1995.404 Wu, 1996, Role of NHE3 in mediating renal brush border Na+-H+ exchange. Adaptation to metabolic acidosis, J Biol Chem, 271, 32749, 10.1074/jbc.271.51.32749 Biemesderfer, 1993, NHE3: A Na/H exchanger isoform of renal brush border, Am J Physiol, 265, F736 Ambühl, 1996, Chronic metabolic acidosis increases NHE3 protein abundance in rat kidney, Am J Physiol, 271, F917 Amemiya, 1995, Acid incubation increases NHE-3 mRNA abundance in OKP cells, Am J Physiol, 269, C126, 10.1152/ajpcell.1995.269.1.C126 Preisig, 1988, Chronic metabolic acidosis causes an adaptation in the apical membrane Na/H antiporter and basolateral membrane Na(HCO3)3 symporter in the rat proximal convoluted tubule, J Clin Invest, 82, 1445, 10.1172/JCI113750 Chu, 1996, EndothelinB receptor activates NHE-3 by a Ca2+-dependent pathway in OKP cells, J Clin Invest, 97, 1454, 10.1172/JCI118567 Eiam-Ong, 1992, Endothelin-1 stimulates the Na+/H+ and Na+/HCO3− transporters in rabbit renal cortex, Kidney Int, 42, 18, 10.1038/ki.1992.255 Guntupalli, 1994, Effects of endothelin on rat renal proximal tubule Na+-Pi cotransport and Na+/H+ exchange, Am J Physiol, 266, F658 Peng, 2001, ETB receptor activation causes exocytic insertion of NHE3 in OKP cells, Am J Physiol, 280, F34 Peng, 1999, ETB receptor activation leads to activation and phosphorylation of NHE3, Am J Physiol, 276, C938, 10.1152/ajpcell.1999.276.4.C938 Laghmani, 2001, Endothelin-1/endothelin-B receptor-mediated increases in NHE3 activity in chronic metabolic acidosis, J Clin Invest, 107, 1563, 10.1172/JCI11234 Yanagisawa, 1988, A novel potent vasoconstrictor peptide produced by vascular endothelial cells, Nature, 332, 411, 10.1038/332411a0 Rubanyi, 1994, Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology, Pharmacol Rev, 46, 325 Suzuki, 1993, Endothelin-1 is produced and secreted by neonatal rat cardiac myocytes in vitro, Biochem Biophys Res Comm, 191, 823, 10.1006/bbrc.1993.1291 Goto, 1995, Endothelin versatility, Nature, 375, 539, 10.1038/375539a0 Sakai, 1996, Endogenous endothelin-1 participates in the maintenance of cardiac function in rats with congestive heart failure, Circulation, 93, 1214, 10.1161/01.CIR.93.6.1214 Sakai, 1996, Inhibition of myocardial endothelin pathway improves long-term survival in heart failure, Nature, 384, 353, 10.1038/384353a0 Shapiro, 1997, Pathogenesis of cardiac dysfunction during metabolic acidosis: therapeutic implications, Kidney Int, 52Suppl 61, S47 Zhou, 1991, Contractile dysfunction during metabolic acidosis: Role of impaired energy metabolism, Am J Physiol, 261, H1481 Morimoto, 1996, Extramyocardial acidosis impairs cardiac resuscitability in isolated, perfused, rat hearts, Crit Care Med, 24, 1719, 10.1097/00003246-199610000-00020 Kumar, 1986, 23Na NMR spectroscopy of proximal tubule suspensions, Kidney Int, 29, 747, 10.1038/ki.1986.61 Huang, 2000, G1 kinases and transforming growth factor-β signaling are associated with a growth pattern switch in diabetes-induced renal growth, Kidney Int, 58, 162, 10.1046/j.1523-1755.2000.00151.x Poggioli, 1992, Effects of angiotensin II and nonpeptide receptor antagonists on transduction pathways in rat proximal tubule, Am J Physiol, 263, C750, 10.1152/ajpcell.1992.263.4.C750 Shankland, 1994, Expression of transforming growth factor-β1 during diabetic renal hypertrophy, Kidney Int, 46, 430, 10.1038/ki.1994.291 Shankland, 1995, Expression of growth-related protooncogenes during diabetic renal hypertrophy, Kidney Int, 47, 782, 10.1038/ki.1995.119 Aruga, 2000, Chronic metabolic acidosis increases NaDC-1 mRNA and protein abundance in rat kidney, Kidney Int, 58, 206, 10.1046/j.1523-1755.2000.00155.x Laghmani, 1997, Chronic metabolic acidosis enhances NHE-3 protein abundance and transport activity in the rat thick ascending limb by increasing NHE-3 mRNA, J Clin Invest, 99, 24, 10.1172/JCI119128 Chen, 1993, Endothelin-1 mRNA in glomerular and epithelial cells of kidney, Am J Physiol, 265, F542 Sakurai, 1991, cDNA cloning, sequence analysis and tissue distribution of rat preproendothelin-1 mRNA, Biochem Biophys Res Comm, 175, 44, 10.1016/S0006-291X(05)81197-0 Ujiie, 1992, Messenger RNA expression and synthesis of endothelin-1 along rat nephron segments, J Clin Invest, 90, 1043, 10.1172/JCI115918 Alpern, 1997, The clinical spectrum of chronic metabolic acidosis: Homeostatic mechanisms produce significant morbidity, Am J Kidney Dis, 29, 291, 10.1016/S0272-6386(97)90045-7 Yang, 2000, Acid incubation causes exocytic insertion of NHE3 in OKP cells, Am J Physiol, 279, C410, 10.1152/ajpcell.2000.279.2.C410 Laghmani, 2002, Role of endothelin in proximal tubule proton secretion and the adaptation to a chronic metabolic acidosis, J Nephrol, 15, S75