Cancer stemness and metastasis: Therapeutic consequences and perspectives
Tóm tắt
Từ khóa
Tài liệu tham khảo
Brabletz, 2005, Opinion: migrating cancer stem cells – an integrated concept of malignant tumour progression, Nat Rev Cancer, 5, 744, 10.1038/nrc1694
Visvader, 2008, Cancer stem cells in solid tumours: accumulating evidence and unresolved questions, Nat Rev Cancer, 8, 755, 10.1038/nrc2499
Quintana, 2008, Efficient tumour formation by single human melanoma cells, Nature, 456, 593, 10.1038/nature07567
Mani, 2008, The epithelial-mesenchymal transition generates cells with properties of stem cells, Cell, 133, 704, 10.1016/j.cell.2008.03.027
Jiang, 2008, Hedgehog signaling in development and cancer, Dev Cell, 15, 801, 10.1016/j.devcel.2008.11.010
Koch, 2007, Notch and cancer: a double-edged sword, Cell Mol Life Sci, 64, 2746, 10.1007/s00018-007-7164-1
Ben-Porath, 2008, An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors, Nat Genet, 40, 499, 10.1038/ng.127
Thiery, 2002, Epithelial-mesenchymal transitions in tumour progression, Nat Rev Cancer, 2, 442, 10.1038/nrc822
Friedl, 2003, Tumour-cell invasion and migration: diversity and escape mechanisms, Nat Rev Cancer, 3, 362, 10.1038/nrc1075
Fodde, 2007, Wnt/beta-catenin signaling in cancer stemness and malignant behavior, Curr Opin Cell Biol, 19, 150, 10.1016/j.ceb.2007.02.007
Wicki, 2006, Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton, Cancer Cell, 9, 261, 10.1016/j.ccr.2006.03.010
Tsuji, 2009, Epithelial-mesenchymal transition and cell cooperativity in metastasis, Cancer Res, 69, 7135, 10.1158/0008-5472.CAN-09-1618
Tsuji, 2008, Epithelial-mesenchymal transition induced by growth suppressor p12CDK2-AP1 promotes tumor cell local invasion but suppresses distant colony growth, Cancer Res, 68, 10377, 10.1158/0008-5472.CAN-08-1444
Pantel, 2008, Detection, clinical relevance and specific biological properties of disseminating tumour cells, Nat Rev Cancer, 8, 329, 10.1038/nrc2375
Al-Hajj, 2003, Prospective identification of tumorigenic breast cancer cells, Proc Natl Acad Sci USA, 100, 3983, 10.1073/pnas.0530291100
Balic, 2006, Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype, Clin Cancer Res, 12, 5615, 10.1158/1078-0432.CCR-06-0169
Gudjonsson, 2002, Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties, Genes Dev, 16, 693, 10.1101/gad.952602
Alix-Panabieres, 2007, Detection and characterization of putative metastatic precursor cells in cancer patients, Clin Chem, 53, 537, 10.1373/clinchem.2006.079509
Watson, 2007, Isolation and molecular profiling of bone marrow micrometastases identifies TWIST1 as a marker of early tumor relapse in breast cancer patients, Clin Cancer Res, 13, 5001, 10.1158/1078-0432.CCR-07-0024
Munz, 2009, The emerging role of EpCAM in cancer and stem cell signaling, Cancer Res, 69, 5627, 10.1158/0008-5472.CAN-09-0654
Gires, 2009, On the abundance of EpCAM on cancer stem cells, Nat Rev Cancer, 9, 143, 10.1038/nrc2499-c1
Aktas, 2009, Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients, Breast Cancer Res, 11, R46, 10.1186/bcr2333
Taniguchi, 2000, Prognostic significance of reverse transcriptase-polymerase chain reaction measurement of carcinoembryonic antigen mRNA levels in tumor drainage blood and peripheral blood of patients with colorectal carcinoma, Cancer, 89, 970, 10.1002/1097-0142(20000901)89:5<970::AID-CNCR5>3.0.CO;2-S
Wind, 2009, Circulating tumour cells during laparoscopic and open surgery for primary colonic cancer in portal and peripheral blood, Eur J Surg Oncol, 35, 942, 10.1016/j.ejso.2008.12.003
Koch, 2001, Comparative analysis of tumor cell dissemination in mesenteric, central, and peripheral venous blood in patients with colorectal cancer, Arch Surg, 136, 85, 10.1001/archsurg.136.1.85
Johnstone, 2002, Apoptosis: a link between cancer genetics and chemotherapy, Cell, 108, 153, 10.1016/S0092-8674(02)00625-6
Stassi, 2003, Thyroid cancer resistance to chemotherapeutic drugs via autocrine production of interleukin-4 and interleukin-10, Cancer res, 63, 6784
Dancescu, 1992, Interleukin 4 protects chronic lymphocytic leukemic B cells from death by apoptosis and upregulates Bcl-2 expression, J Exp Med, 176, 1319, 10.1084/jem.176.5.1319
Conticello, 2004, IL-4 protects tumor cells from anti-CD95 and chemotherapeutic agents via up-regulation of antiapoptotic proteins, J Immunol, 172, 5467, 10.4049/jimmunol.172.9.5467
Prokopchuk, 2005, Interleukin-4 enhances proliferation of human pancreatic cancer cells: evidence for autocrine and paracrine actions, Br J Cancer, 92, 921, 10.1038/sj.bjc.6602416
Todaro, 2007, Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4, Cell Stem Cell, 1, 389, 10.1016/j.stem.2007.08.001
Diehn, 2009, Association of reactive oxygen species levels and radioresistance in cancer stem cells, Nature, 458, 780, 10.1038/nature07733
Tammam, 2009, Down-regulation of the Notch pathway mediated by a gamma-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia, Br J Pharmacol, 158, 1183, 10.1111/j.1476-5381.2009.00389.x
Feldmann, 2008, An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer, Mol Cancer Ther, 7, 2725, 10.1158/1535-7163.MCT-08-0573
Rudin, 2009, Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449, N Engl J Med, 361, 1173, 10.1056/NEJMoa0902903
Bar, 2007, Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma, Stem Cells, 25, 2524, 10.1634/stemcells.2007-0166
Jiang, 2008, Role of mTOR in anticancer drug resistance: perspectives for improved drug treatment, Drug Resist Updat, 11, 63, 10.1016/j.drup.2008.03.001
Yilmaz, 2006, Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells, Nature, 441, 475, 10.1038/nature04703
Zhou, 2007, Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance, Proc Natl Acad Sci USA, 104, 16158, 10.1073/pnas.0702596104
Dubrovska, 2009, The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations, Proc Natl Acad Sci USA, 106, 268, 10.1073/pnas.0810956106
Mueller, 2009, Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer, Gastroenterology, 137, 1102, 10.1053/j.gastro.2009.05.053
Gupta, 2009, Identification of selective inhibitors of cancer stem cells by high-throughput screening, Cell, 138, 645, 10.1016/j.cell.2009.06.034
Beug, 2009, Breast cancer stem cells: eradication by differentiation therapy?, Cell, 138, 623, 10.1016/j.cell.2009.08.007
Sell, 2004, Stem cell origin of cancer and differentiation therapy, Crit Rev Oncol Hematol, 51, 1, 10.1016/j.critrevonc.2004.04.007
Hague, 1996, The role of butyrate in human colonic epithelial cells: an energy source or inducer of differentiation and apoptosis?, Proc Nutr Soc, 55, 937, 10.1079/PNS19960090
Plimack, 2007, Decitabine and its role in the treatment of hematopoietic malignancies, Leuk Lymphoma, 48, 1472, 10.1080/10428190701471981
Cheng, 2004, Preferential response of cancer cells to zebularine, Cancer cell, 6, 151, 10.1016/j.ccr.2004.06.023
Marquez, 2005, Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy, Ann NY Acad Sci, 1058, 246, 10.1196/annals.1359.037
Duvic, 2007, Vorinostat: a new oral histone deacetylase inhibitor approved for cutaneous T-cell lymphoma, Expert Opin Investig Drugs, 16, 1111, 10.1517/13543784.16.7.1111
Benedetti, 2000, Gene therapy of experimental brain tumors using neural progenitor cells, Nat Med, 6, 447, 10.1038/74710
Aboody, 2000, Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas, Proc Natl Acad Sci USA, 97, 12846, 10.1073/pnas.97.23.12846
Aboody, 2006, Development of a tumor-selective approach to treat metastatic cancer, PLoS One, 1, e23, 10.1371/journal.pone.0000023
Aboody, 2006, Targeting of melanoma brain metastases using engineered neural stem/progenitor cells, Neurooncology, 8, 119
Fodde, 2006, Stem cells and metastatic cancer: fatal attraction?, PLoS Med, 3, e482, 10.1371/journal.pmed.0030482