DLS and zeta potential – What they are and what they are not?

Treuel, 2014, Physicochemical characterization of nanoparticles and their behavior in the biological environment, Phys. Chem. Chem. Phys., 16, 15053, 10.1039/C4CP00058G Akbarzadeh, 2012, Magnetic nanoparticles: preparation, physical properties, and applications in biomedicine, Nanoscale Res. Lett., 7, 144, 10.1186/1556-276X-7-144 Bhattacharjee, 2012, Cytotoxicity and cellular uptake of tri-block copolymer nanoparticles with different size and surface characteristics, Part. Fibre Toxicol., 9, 11, 10.1186/1743-8977-9-11 Bhattacharjee, 2010, Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells, Part. Fibre Toxicol., 7, 25, 10.1186/1743-8977-7-25 Favi, 2015, Shape and surface effects on the cytotoxicity of nanoparticles: gold nanospheres versus gold nanostars, J. Biomed. Mater. Res. A, 103, 3449, 10.1002/jbm.a.35491 Jokerst, 2011, Nanoparticle PEGylation for imaging and therapy, Nanomedicine (London), 6, 715, 10.2217/nnm.11.19 Kong, 2011, Experimental considerations on the cytotoxicity of nanoparticles, Nanomedicine (London), 6, 929, 10.2217/nnm.11.77 Selim, 2012, Effect of the surface texture and crystallinity of ZnO nanoparticles on their toxicity, Mater. Sci. Eng. C, 32, 2356, 10.1016/j.msec.2012.07.007 Alshehri, 2012, Enhanced electrical conductivity of silver nanoparticles for high frequency electronic applications, ACS Appl. Mater. Interfaces, 4, 7007, 10.1021/am3022569 Shi, 2015, Photo-fluorescent and magnetic properties of iron oxide nanoparticles for biomedical applications, Nanoscale, 7, 8209, 10.1039/C5NR01538C Nealon, 2012, Magnetism in gold nanoparticles, Nanoscale, 4, 5244, 10.1039/c2nr30640a Chen, 2016, Nanochemistry and nanomedicine for nanoparticle-based diagnostics and therapy, Chem. Rev., 116, 2826, 10.1021/acs.chemrev.5b00148 Fröhlich, 2012, The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles, Int. J. Nanomedicine, 7, 5577, 10.2147/IJN.S36111 Bhattacharjee, 2013, Cytotoxicity of surface-functionalized silicon and germanium nanoparticles: the dominant role of surface charges, Nanoscale, 5, 4870, 10.1039/c3nr34266b Axson, 2015, Rapid kinetics of size and pH-dependent dissolution and aggregation of silver nanoparticles in simulated gastric fluid, J. Phys. Chem. C, 119, 20632, 10.1021/acs.jpcc.5b03634 Blanco, 2015, Principles of nanoparticle design for overcoming biological barriers to drug delivery, Nat. Biotechnol., 33, 941, 10.1038/nbt.3330 Singh, 2009, Nanoparticle-based targeted drug delivery, Exp. Mol. Pathol., 86, 215, 10.1016/j.yexmp.2008.12.004 Takedatsu, 2015, Nanomedicine and drug delivery strategies for treatment of inflammatory bowel disease, World J. Gastroenterol., 21, 11343, 10.3748/wjg.v21.i40.11343 Ritz, 2015, Protein corona of nanoparticles: distinct proteins regulate the cellular uptake, Biomacromolecules, 16, 1311, 10.1021/acs.biomac.5b00108 Lundqvist, 2013, Nanoparticles: tracking protein corona over time, Nat. Nanotechnol., 8, 701, 10.1038/nnano.2013.196 Digman, 2011, Lessons in fluctuation correlation spectroscopy, Annu. Rev. Phys. Chem., 62, 645, 10.1146/annurev-physchem-032210-103424 Dzakpasu, 2004, Dynamic light scattering microscopy. A novel optical technique to image submicroscopic motions. I: theory, Biophys. J., 87, 1279, 10.1529/biophysj.103.033837 Kalaitzaki, 2015, Biocompatible colloidal dispersions as potential formulations of natural pyrethrins: a structural and efficacy study, Langmuir, 31, 5722, 10.1021/acs.langmuir.5b00246 Satoh, 1999, Brownian dynamics simulations of ferromagnetic colloidal dispersions in a simple shear flow, J. Colloid Interface Sci., 209, 44, 10.1006/jcis.1998.5826 Dalstein, 2015, Revealing the interplay between adsorbed molecular layers and gold nanoparticles by linear and nonlinear optical properties, J. Phys. Chem. C, 119, 17146, 10.1021/acs.jpcc.5b03601 Lim, 2013, Characterization of magnetic nanoparticle by dynamic light scattering, Nanoscale Res. Lett., 8, 381, 10.1186/1556-276X-8-381 Delgado, 2007, Measurement and interpretation of electrokinetic phenomena, J. Colloid Interface Sci., 309, 194, 10.1016/j.jcis.2006.12.075 Rademeyer, 2015, Microfluidic system for high throughput characterisation of echogenic particles, Lab Chip, 15, 417, 10.1039/C4LC01206B Fan, 2014, Light scattering and surface plasmons on small spherical particles, Light Sci. Appl. (Nat.), 3, e179, 10.1038/lsa.2014.60 Ross, 2012, Mie scattering by soft core-shell particles and its applications to ellipsometric light scattering, Phys. Rev. E, 85, 056710, 10.1103/PhysRevE.85.056710 Hong, 2006, Size dependence of optical properties and internal structure of plasma grown carbonaceous nanoparticles studied by in situ Rayleigh-Mie scattering ellipsometry, J. Appl. Phys., 100, 064303, 10.1063/1.2338132 Yguerabide, 1998, Light-scattering submicroscopic particles as highly fluorescent analogs and their use as tracer labels in clinical and biological applications: I. Theory, Anal. Biochem., 262, 137, 10.1006/abio.1998.2759 Uemura, 1978, Application of light scattering from dielectric cylinder based upon Mie and Rayleigh-Gans-Born theories to polymer systems. I. Scattering from a glass fiber, Polym. J., 10, 341, 10.1295/polymj.10.341 Meller, 1998, Localized dynamic light scattering: a new approach to dynamic measurements in optical microscopy, Biophys. J., 74, 1541, 10.1016/S0006-3495(98)77866-X Lorber, 2012, Protein analysis by dynamic light scattering: methods and techniques for students, Biochem. Mol. Biol. Educ., 40, 372, 10.1002/bmb.20644 Gilroy, 2011, Viscosity of aqueous DNA solutions determined using dynamic light scattering, Analyst, 136, 4159, 10.1039/c1an15475c Naiim, 2015, Multiangle dynamic light scattering for the improvement of multimodal particle size distribution measurements, Soft Matter, 11, 28, 10.1039/C4SM01995D Santiago, 2008, Dynamic light scattering and optical absorption spectroscopy study of pH and temperature stabilities of the extracellular hemoglobin of Glossoscolex paulistus, Biophys. J., 94, 2228, 10.1529/biophysj.107.116780 Filipe, 2010, Critical evaluation of nanoparticle tracking analysis (NTA) by NanoSight for the measurement of nanoparticles and protein aggregates, Pharm. Res., 27, 796, 10.1007/s11095-010-0073-2 Bolintineanu, 2014, Particle dynamics modeling methods for colloid suspensions, Comput. Part. Mech., 1, 321, 10.1007/s40571-014-0007-6 Min, 2008, The role of interparticle and external forces in nanoparticle assembly, Nat. Mater., 7, 527, 10.1038/nmat2206 Lesniak, 2012, Effects of the presence or absence of a protein corona on silica nanoparticle uptake and impact on cells, ACS Nano, 6, 5845, 10.1021/nn300223w Wan, 2015, The “sweet” side of the protein corona: effects of glycosylation on nanoparticle–cell interactions, ACS Nano, 9, 2157, 10.1021/nn506060q Fleischer, 2014, Nanoparticle–cell interactions: molecular structure of the protein corona and cellular outcomes, Acc. Chem. Res., 47, 2651, 10.1021/ar500190q Milani, 2012, Reversible versus irreversible binding of transferrin to polystyrene nanoparticles: soft and hard corona, ACS Nano, 6, 2532, 10.1021/nn204951s Liu, 2013, Protein corona formation for nanomaterials and proteins of a similar size: hard or soft corona?, Nanoscale, 5, 1658, 10.1039/c2nr33611a Lazzari, 2012, Colloidal stability of polymeric nanoparticles in biological fluids, J. Nanopart. Res., 14, 920, 10.1007/s11051-012-0920-7 Khan, 2015, Kinetics of protein adsorption on gold nanoparticle with variable protein structure and nanoparticle size, J. Chem. Phys., 143, 164709, 10.1063/1.4934605 Alexis, 2008, Factors affecting the clearance and biodistribution of polymeric nanoparticles, Mol. Pharm., 5, 505, 10.1021/mp800051m Salvati, 2013, Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface, Nat. Nanotechnol., 8, 137, 10.1038/nnano.2012.237 Hawe, 2011, Taylor dispersion analysis compared to dynamic light scattering for the size analysis of therapeutic peptides and proteins and their aggregates, Pharm. Res., 28, 2302, 10.1007/s11095-011-0460-3 Dobrovolskaia, 2014, Protein corona composition does not accurately predict hematocompatibility of colloidal gold nanoparticles, Nanomedicine: NBM, 10, 1453, 10.1016/j.nano.2014.01.009 Hadjidemetriou, 2016, Time-evolution of in vivo protein corona onto blood-circulating PEGylated liposomal doxorubicin (DOXIL) nanoparticles, Nanoscale, 8, 6948, 10.1039/C5NR09158F Boal, 2000, Self-assembly of nanoparticles into structured spherical and network aggregates, Nature, 404, 746, 10.1038/35008037 Urena-Benavides, 2012, Static light scattering of triaxial nanoparticle suspensions in the Rayleigh-Gans-Debye regime: application to cellulose nanocrystals, RSC Adv., 2, 1096, 10.1039/C1RA00391G de Kort, 2015, Nanoparticle diffusometry for quantitative assessment of submicron structure in food biopolymer networks, Trends Food Sci. Technol., 42, 13, 10.1016/j.tifs.2014.11.003 Ling, 2013, A colorimetric method for the molecular weight determination of polyethylene glycol using gold nanoparticles, Nanoscale Res. Lett., 8, 538, 10.1186/1556-276X-8-538 Amin, 2014, Protein aggregation, particle formation, characterization & rheology, Curr. Opin. Colloid Interface Sci., 19, 438, 10.1016/j.cocis.2014.10.002 Maulucci, 2005, Particle size distribution in DMPC vesicles solutions undergoing different sonication times, Biophys. J., 88, 3545, 10.1529/biophysj.104.048876 Varga, 2014, Towards traceable size determination of extracellular vesicles, J. Extracell. Vesicles, 3, 10.3402/jev.v3.23298 Mastan, 2015, A molecular weight distribution polydispersity equation for the ATRP system: quantifying the effect of radical termination, Macromolecules, 48, 6440, 10.1021/acs.macromol.5b01525 Pohl, 2012, Ultra-rapid absorption of recombinant human insulin induced by zinc chelation and surface charge masking, J. Diabetes Sci. Technol., 6, 755, 10.1177/193229681200600404 Finnigan, 1970, Light scattering from benzene, toluene, carbon disulphide and carbon tetrachloride, Chem. Phys. Lett., 6, 141, 10.1016/0009-2614(70)80200-7 Noday, 2009, Viscosity of cryoprotective agents near glass transition: a new device, technique, and data on DMSO, DP6, and VS55, Exp. Mech., 49, 663, 10.1007/s11340-008-9191-8 Chanamai, 2000, Creaming stability of flocculated monodisperse oil-in-water emulsions, J. Colloid Interface Sci., 225, 214, 10.1006/jcis.2000.6766 Panchal, 2014, Analyzing subvisible particles in protein drug products: a comparison of dynamic light scattering (DLS) and resonant mass measurement (RMM), AAPS J., 16, 440, 10.1208/s12248-014-9579-6 Müller, 2014, The effect of particle agglomeration on the formation of a surface-connected compartment induced by hydroxyapatite nanoparticles in human monocyte-derived macrophages, Biomaterials, 35, 1074, 10.1016/j.biomaterials.2013.10.041 Zheng, 2016, A simple and fast method to study the hydrodynamic size difference of protein disulfide isomerase in oxidized and reduced form using gold nanoparticles and dynamic light scattering, Analyst, 141, 934, 10.1039/C5AN02248G Karow, 2015, Resolving power of dynamic light scattering for protein and polystyrene nanoparticles, Pharm. Dev. Technol., 20, 84, 10.3109/10837450.2014.910808 Meng, 2013, Aggregation rate and fractal dimension of fullerene nanoparticles via simultaneous multiangle static and dynamic light scattering measurement, J. Colloid Interface Sci., 392, 27, 10.1016/j.jcis.2012.09.088 Gei, 2015, Resch-Genger, effect of fluorescent staining on size measurements of polymeric nanoparticles using DLS and SAXS, Anal. Methods, 7, 9785, 10.1039/C5AY02005K Murdock, 2008, Characterization of nanomaterial dispersion in solution prior to in vitro exposure using dynamic light scattering technique, Toxicol. Sci., 101, 239, 10.1093/toxsci/kfm240 Liu, 2011, Analysis of nanoparticle agglomeration in aqueous suspensions via constant-number Monte Carlo simulation, Environ. Sci. Technol., 45, 9284, 10.1021/es202134p De Jong, 2008, Drug delivery and nanoparticles: applications and hazards, Int. J. Nanomedicine, 3, 133, 10.2147/IJN.S596 Zhou, 2015, Concomitant Raman spectroscopy and dynamic light scattering for characterization of therapeutic proteins at high concentrations, Anal. Biochem., 472, 7, 10.1016/j.ab.2014.11.016 Niu, 2015, Highly symmetric gold nanostars: crystallographic control and surface-enhanced Raman scattering property, J. Am. Chem. Soc., 137, 10460, 10.1021/jacs.5b05321 Zhang, 2013, The road for nanomaterials industry: a review of carbon nanotube production, post-treatment, and bulk applications for composites and energy storage, Small, 9, 1237, 10.1002/smll.201203252 Nair, 2008, Dynamics of surfactant-suspended single-walled carbon nanotubes in a centrifugal field, Langmuir, 24, 1790, 10.1021/la702516u Lee, 2014, Self-propelling nanomotors in the presence of strong Brownian forces, Nano Lett., 14, 2407, 10.1021/nl500068n Kaszuba, 2007, Resolving concentrated particle size mixtures using dynamic light scattering, Part. Part. Syst. Charact., 24, 159, 10.1002/ppsc.200601035 de Kanter, 2016, Enabling the measurement of particle sizes in stirred colloidal suspensions by embedding dynamic light scattering into an automated probe head, Measurement, 80, 92, 10.1016/j.measurement.2015.11.024 Bouri, 2015, A novel approach to size separation of gold nanoparticles by capillary electrophoresis-evaporative light scattering detection, RSC Adv., 5, 16672, 10.1039/C4RA17217E Duan, 2011, Viscosity affected by nanoparticle aggregation in Al2O3-water nanofluids, Nanoscale Res. Lett., 6, 1, 10.1186/1556-276X-6-248 Grouchko, 2014, Merging of metal nanoparticles driven by selective wettability of silver nanostructures, Nat. Commun., 5 Hagendorfer, 2012, Characterization of silver nanoparticle products using asymmetric flow field flow fractionation with a multidetector approach – a comparison to transmission electron microscopy and batch dynamic light scattering, Anal. Chem., 84, 2678, 10.1021/ac202641d Zhao, 2015, Thermal responsive fluorescent nanocomposites based on carbon dots, RSC Adv., 5, 15187, 10.1039/C4RA13417F Kim, 2015, TEM based high resolution and low-dose scanning electron nanodiffraction technique for nanostructure imaging and analysis, Micron, 71, 39, 10.1016/j.micron.2015.01.002 Zhou, 2004, In situ UHV-TEM investigation of the kinetics of initial stages of oxidation on the roughened Cu(110) surface, Surf. Sci., 559, 100, 10.1016/j.susc.2004.04.046 Mansfield, 2015, POZylation: a new approach to enhance nanoparticle diffusion through mucosal barriers, Nanoscale, 7, 13671, 10.1039/C5NR03178H Klapetek, 2011, Atomic force microscopy analysis of nanoparticles in non-ideal conditions, Nanoscale Res. Lett., 6, 1, 10.1186/1556-276X-6-514 Lamprecht, 2014, Applications of biosensing atomic force microscopy in monitoring drug and nanoparticle delivery, Expert Opin. Drug Deliv., 11, 1237, 10.1517/17425247.2014.917078 Fielding, 2012, Correcting for a density distribution: particle size analysis of core–shell nanocomposite particles using disk centrifuge photosedimentometry, Langmuir, 28, 2536, 10.1021/la204841n Krpetić, 2013, High-resolution sizing of monolayer-protected gold clusters by differential centrifugal sedimentation, ACS Nano, 7, 8881, 10.1021/nn403350v Ziegler, 2005, Comparison of cascade impaction and laser diffraction for particle size distribution measurements, J. Aerosol Med., 18, 311, 10.1089/jam.2005.18.311 Sabuncu, 2012, Probing nanoparticle interactions in cell culture media, Colloids Surf. B: Biointerfaces, 95, 96, 10.1016/j.colsurfb.2012.02.022 Maiorano, 2010, Effects of cell culture media on the dynamic formation of protein–nanoparticle complexes and influence on the cellular response, ACS Nano, 4, 7481, 10.1021/nn101557e Singh, 2006, Study of smoke aerosols under a controlled environment by using dynamic light scattering, Appl. Opt., 45, 2217, 10.1364/AO.45.002217 Durian, 1991, Multiple light-scattering probes of foam structure and dynamics, Science, 252, 686, 10.1126/science.252.5006.686 Kaszuba, 2010, High-concentration zeta potential measurements using light-scattering techniques, Philos. Transact. A Math. Phys. Eng. Sci., 368, 4439, 10.1098/rsta.2010.0175 Montes Ruiz-Cabello, 2014, Electric double-layer potentials and surface regulation properties measured by colloidal-probe atomic force microscopy, Phys. Rev. E, 90, 012301, 10.1103/PhysRevE.90.012301 Chen, 2013, Anisotropic Debye model for the thermal boundary conductance, Phys. Rev. B, 87, 125426, 10.1103/PhysRevB.87.125426 Vidal-Iglesias, 2012, Understanding the Nernst equation and other electrochemical concepts: an easy experimental approach for students, J. Chem. Educ., 89, 936, 10.1021/ed2007179 Thakkar, 2011, Formulation and characterization of lipid-based drug delivery system of raloxifene-microemulsion and self-microemulsifying drug delivery system, J. Pharm. Bioallied Sci., 3, 442, 10.4103/0975-7406.84463 Ito, 2004, Comparison of nanoparticle size and electrophoretic mobility measurements using a carbon-nanotube-based coulter counter, dynamic light scattering, transmission electron microscopy, and phase analysis light scattering, Langmuir, 20, 6940, 10.1021/la049524t Shilov, 2004, Electroacoustic theory for concentrated colloids with overlapped DLs at arbitrary κa: I. Application to nanocolloids and nonaqueous colloids, J. Colloid Interface Sci., 277, 347, 10.1016/j.jcis.2004.04.052 Uskoković, 2010, Zeta-potential and particle size analysis of human amelogenins, J. Dent. Res., 89, 149, 10.1177/0022034509354455 Kirkwood, 2015, Using isoelectric point to determine the pH for initial protein crystallization trials, Bioinformatics, 31, 1444, 10.1093/bioinformatics/btv011 Salis, 2011, Measurements and theoretical interpretation of points of zero charge/potential of BSA protein, Langmuir, 27, 11597, 10.1021/la2024605 Nägele, 1989, The transient zeta potential of hydrating cement, Chem. Eng. Sci., 44, 1637, 10.1016/0009-2509(89)80006-5 Patel, 2011, Nanosuspension: an approach to enhance solubility of drugs, J. Adv. Pharm. Technol. Res., 2, 81, 10.4103/2231-4040.82950 Missana, 2000, On the applicability of DLVO theory to the prediction of clay colloids stability, J. Colloid Interface Sci., 230, 150, 10.1006/jcis.2000.7003 Leite, 2012, Theoretical models for surface forces and adhesion and their measurement ssing atomic force microscopy, Int. J. Mol. Sci., 13, 12773, 10.3390/ijms131012773 Kim, 2014, Surface treatment of silica nanoparticles for stable and charge-controlled colloidal silica, Int. J. Nanomedicine, 9, 29 Almeida, 2015, Evaluation of the stability of concentrated emulsions for lemon beverages using sequential experimental designs, PLoS One, 10, e0118690, 10.1371/journal.pone.0118690 Kouchakzadeh, 2010, Optimization of PEGylation conditions for BSA nanoparticles using response surface methodology, AAPS PharmSciTech, 11, 1206, 10.1208/s12249-010-9487-8 Pillai, 2016, Electrostatic titrations reveal surface compositions of mixed, on-nanoparticle monolayers comprising positively and negatively charged ligands, J. Phys. Chem. C, 120, 4139, 10.1021/acs.jpcc.5b12599 Clavier, 2015, Surface charging behavior of nanoparticles by considering site distribution and density, dielectric constant and pH changes - a Monte Carlo approach, Phys. Chem. Chem. Phys., 17, 4346, 10.1039/C4CP04733H Di Marco, 2007, Physicochemical characterization of ultrasmall superparamagnetic iron oxide particles (USPIO) for biomedical application as MRI contrast agents, Int. J. Nanomedicine, 2, 609 Hedberg, 2013, Surface-protein interactions on different stainless steel grades: effects of protein adsorption, surface changes and metal release, J. Mater. Sci. Mater. Med., 24, 1015, 10.1007/s10856-013-4859-8 Tucker, 2015, Laser Doppler electrophoresis applied to colloids and surfaces, Curr. Opin. Colloid Interface Sci., 20, 215, 10.1016/j.cocis.2015.07.001 Satzer, 2016, Protein adsorption onto nanoparticles induces conformational changes: particle size dependency, kinetics, and mechanisms, Eng. Life Sci., 16, 238, 10.1002/elsc.201500059 Dobrovolskaia, 2013, Understanding the correlation between in vitro and in vivo immunotoxicity tests for nanomedicines, J. Control. Release, 172, 456, 10.1016/j.jconrel.2013.05.025 Kim, 2014, Suppression of nanoparticle cytotoxicity approaching in vivo serum concentrations: limitations of in vitro testing for nanosafety, Nanoscale, 6, 14180, 10.1039/C4NR04970E Lu, 2011, In vitro-in vivo correlation: perspectives on model development, Int. J. Pharm., 418, 142, 10.1016/j.ijpharm.2011.01.010