CK2 phosphorylation of the PRH/Hex homeodomain functions as a reversible switch for DNA binding
Tóm tắt
Từ khóa
Tài liệu tham khảo
Whitmarsh, 2000, Regulation of transcription factor function by phosphorylation, Cell Mol. Life Sci., 57, 1172, 10.1007/PL00000757
Ahmed, 2002, Joining the cell survival squad: an emerging role for protein kinase CK2, Trends Cell Biol., 12, 226, 10.1016/S0962-8924(02)02279-1
Meggio, 2003, One-thousand-and-one substrates of protein kinase CK2?, FASEB J., 17, 349, 10.1096/fj.02-0473rev
Litchfield, 2003, Protein kinase CK2: structure, regulation and role in cellular decisions of life and death, Biochem. J., 369, 1, 10.1042/bj20021469
Jaffe, 1997, A role for phosphorylation by casein kinase II in modulating Antennapedia activity in Drosophila, Genes Dev., 11, 1327, 10.1101/gad.11.10.1327
Li, 1999, Allosteric regulation of even-skipped repression activity by phosphorylation, Mol. Cell, 3, 77, 10.1016/S1097-2765(00)80176-8
Maizel, 2002, Engrailed homeoprotein secretion is a regulated process, Development, 129, 3545, 10.1242/dev.129.15.3545
Bourbon, 1995, Phosphorylation of the Drosophila engrailed protein at a site outside its homeodomain enhances DNA binding, J. Biol. Chem., 270, 11130, 10.1074/jbc.270.19.11130
Fienberg, 1999, Phylogenetically conserved CK-II phosphorylation site of the murine homeodomain protein Hoxb-6, J. Exp. Zool., 285, 76, 10.1002/(SICI)1097-010X(19990415)285:1<76::AID-JEZ9>3.0.CO;2-K
Coqueret, 1998, DNA binding by cut homeodomain proteins is down-modulated by casein kinase II, J. Biol. Chem., 273, 2561, 10.1074/jbc.273.5.2561
Kasahara, 1999, Identification of the in vivo casein kinase II phosphorylation site within the homeodomain of the cardiac tisue-specifying homeobox gene product Csx/Nkx2.5, Mol. Cell Biol., 19, 526, 10.1128/MCB.19.1.526
Ford, 2000, Cell cycle-regulated phosphorylation of the human SIX1 homeodomain protein, J. Biol. Chem., 275, 22245, 10.1074/jbc.M002446200
Crompton, 1992, Identification of a novel vertebrate homeobox gene expressed in haematopoietic cells, Nucleic Acids Res., 20, 5661, 10.1093/nar/20.21.5661
Soufi, 2008, PRH/Hex: an oligomeric transcription factor and multifunctional regulator of cell fate, Biochem. J., 412, 399, 10.1042/BJ20080035
Brickman, 2000, Hex is a transcriptional repressor that contributes to anterior identity and suppresses Spemann organiser function, Development, 127, 2303, 10.1242/dev.127.11.2303
Foley, 2005, Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex, Genes Dev., 19, 387, 10.1101/gad.1279405
Ho, 1999, A role for the extraembryonic yolk syncytial layer in patterning the zebrafish embryo suggested by properties of the hex gene, Curr. Biol., 9, 1131, 10.1016/S0960-9822(99)80485-0
Thomas, 1998, Hex: a homeobox gene revealing peri-implantation asymmetry in the mouse embryo and an early transient marker of endothelial cell precursors, Development, 125, 85, 10.1242/dev.125.1.85
Bogue, 2003, Impaired B cell development and function in mice with a targeted disruption of the homeobox gene Hex, Proc. Natl Acad. Sci. USA, 100, 556, 10.1073/pnas.0236979100
Guo, 2003, The homeoprotein Hex is required for hemangioblast differentiation, Blood, 102, 2428, 10.1182/blood-2003-02-0634
Jayaraman, 2000, The homeodomain protein PRH influences the differentiation of haematopoietic cells, Leuk. Res., 24, 1023, 10.1016/S0145-2126(00)00072-2
Mack, 2002, Down-regulation of the myeloid homeobox protein Hex is essential for normal T-cell development, Immunology, 107, 444, 10.1046/j.1365-2567.2002.01523.x
Topisirovic, 2003, The proline-rich homeodomain protein, PRH, is a tissue-specific inhibitor of eIF4E-dependent cyclin D1 mRNA transport and growth, EMBO J., 22, 689, 10.1093/emboj/cdg069
Topisirovic, 2003, Aberrant eukaryotic translation initiation factor 4E-dependent mRNA transport impedes hematopoietic differentiation and contributes to leukemogenesis, Mol. Cell Biol., 23, 8992, 10.1128/MCB.23.24.8992-9002.2003
George, 2003, The homeobox gene Hex induces T-cell-derived lymphomas when overexpressed in hematopoietic precursor cells, Oncogene, 22, 6764, 10.1038/sj.onc.1206822
Denson, 2000, Divergent homeobox gene hex regulates promoter of the Na(+)-dependent bile acid cotransporter, Am. J. Physiol. Gastrointest. Liver Physiol., 279, G347, 10.1152/ajpgi.2000.279.2.G347
Soufi, 2006, Oligomerisation of the developmental regulator proline rich homeodomain (PRH/Hex) is mediated by a novel proline-rich dimerisation domain, J. Mol. Biol., 358, 943, 10.1016/j.jmb.2006.02.020
Topcu, 1999, The promyelocytic leukemia protein PML interacts with the proline-rich homeodomain protein PRH: a RING may link hematopoiesis and growth control, Oncogene, 18, 7091, 10.1038/sj.onc.1203201
Guiral, 2001, PRH represses transcription in hematopoietic cells by at least two independent mechanisms, J. Biol. Chem., 276, 2961, 10.1074/jbc.M004948200
Swingler, 2004, The proline-rich homeodomain protein recruits members of the Groucho/Transducin-like enhancer of split protein family to co-repress transcription in hematopoietic cells, J. Biol. Chem., 279, 34938, 10.1074/jbc.M404488200
Desjobert, 2009, The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE corepressors, Biochem. J., 417, 121, 10.1042/BJ20080872
Tanaka, 1999, cDNA cloning and expression of rat homeobox gene, Hex, and functional characterization of the protein, Biochem. J., 339, 111, 10.1042/bj3390111
Schaefer, 2001, Functional interaction of Jun and homeodomain proteins, J. Biol. Chem., 276, 43074, 10.1074/jbc.M102552200
Minami, 2004, Interaction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signaling, J. Biol. Chem., 279, 20626, 10.1074/jbc.M308730200
Kasamatsu, 2004, Identification of the transactivating region of the homeodomain protein, hex, J. Biochem. (Tokyo), 135, 217, 10.1093/jb/mvh025
Bess, 2003, The transcriptional repressor protein PRH interacts with the proteasome, Biochem. J., 374, 667, 10.1042/bj20030769
Grbavec, 1999, Groucho/transducin-like enhancer of split (TLE) family members interact with the yeast transcriptional co-repressor SSN6 and mammalian SSN6- related proteins: implications for evolutionary conservation of transcription repression mechanisms, Biochem. J., 337, 13, 10.1042/bj3370013
Butcher, 2003, Purification of the proline-rich homeodomain protein, J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 786, 3, 10.1016/S1570-0232(02)00740-7
Soufi, 2006, Purification and characterisation of the PRH homeodomain: Removal of the N-terminal domain of PRH increases the PRH homeodomain-DNA interaction, Int. J. Biol. Macromol., 39, 45, 10.1016/j.ijbiomac.2006.01.004
Vilk, 1999, Inducible expression of protein kinase CK2 in mammalian cells. Evidence for functional specialization of CK2 isoforms, J. Biol. Chem., 274, 14406, 10.1074/jbc.274.20.14406
Graham, 2000, The regulatory beta subunit of protein kinase CK2 mediates formation of tetrameric CK2 complexes, J. Biol. Chem., 275, 5003, 10.1074/jbc.275.7.5003
Vilk, 1999, Inducible expression of protein kinase CK2 in mammalian cells. Evidence for functional specialization of CK2 isoforms, J. Biol. Chem., 274, 14406, 10.1074/jbc.274.20.14406
Pfaffl, 2001, A new mathematical model for relative quantification in real-time RT-PCR, Nucleic Acids Res., 29, e45, 10.1093/nar/29.9.e45
Nakagawa, 2003, HEX acts as a negative regulator of angiogenesis by modulating the expression of angiogenesis-related gene in endothelial cells in vitro, Arterioscler. Thromb. Vasc. Biol., 23, 231, 10.1161/01.ATV.0000052670.55321.87
Gille, 2006, Structural interpretation of mutations and SNPs using STRAP-NT, Protein Sci., 15, 208, 10.1110/ps.051882006
DeLano, 2002, The PyMOL Molecular Graphics System