FibroScan-AST (FAST) score for the non-invasive identification of patients with non-alcoholic steatohepatitis with significant activity and fibrosis: a prospective derivation and global validation study

The Lancet Gastroenterology & Hepatology - Tập 5 - Trang 362-373 - 2020
Philip N Newsome1,2,3, Magali Sasso4, Jonathan J Deeks1,5, Angelo Paredes6,7, Jérôme Boursier8,9, Wah-Kheong Chan10, Yusuf Yilmaz11,12, Sébastien Czernichow13, Ming-Hua Zheng14,15, Vincent Wai-Sun Wong16, Michael Allison17, Emmanuel Tsochatzis18, Quentin M Anstee19,20, David A Sheridan21, Peter J Eddowes22, Indra N Guha22, Jeremy F Cobbold23, Valérie Paradis24, Pierre Bedossa20,25, Véronique Miette4
1National Institute for Health Research Biomedical Research Centre at University Hospitals Birmingham NHS Foundation Trust and the University of Birmingham, Birmingham, UK
2Centre for Liver and Gastrointestinal Research, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK
3Liver Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
4R&D Department, Echosens, Paris, France
5Test Evaluation Research Group, Institute of Applied Health Research, University of Birmingham, Birmingham, UK
6Brooke Army Medical Center, Fort Sam, Houston, TX. USA
7Uniformed Services University of the Health Sciences, Bethesda, MD USA
8Department of Hepato-Gastroenterology, Angers University Hospital, Angers, France
9HIFIH Laboratory UPRES EA3859, SFR4208, Angers University, Angers, France
10Gastroenterology and Hepatology Unit, Gastrointestinal Endoscopy Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
11Liver Research Unit, Institute of Gastroenterology, Marmara University, Istanbul, Turkey
12Department of Gastroenterology, School of Medicine, Marmara University, Istanbul, Turkey
13Department of Nutrition, Hôpital Européen Georges-Pompidou (APHP), University of Paris, Paris, France
14NAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
15Institute of Hepatology, Wenzhou Medical University, Wenzhou, China
16Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
17Department of Medicine, Cambridge Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
18UCL Institute for Liver and Digestive Health, Royal Free Hospital and UCL, London, UK
19Institute of Cellular Medicine–Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
20Newcastle NIHR Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, UK
21Institute of Translational and Stratified Medicine, University of Plymouth, Plymouth, UK
22NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, UK
23NIHR Oxford Biomedical Research Centre and Oxford Liver Unit, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK
24Pathology Department, Hôpital Beaujon, APHP, Clichy, France
25Liverpat, Paris, France

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