SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function
Tài liệu tham khảo
Agarwal, 2011, Resveratrol and life extension, Ann. N Y Acad. Sci., 1215, 138, 10.1111/j.1749-6632.2010.05850.x
Banks, 2008, SirT1 gain of function increases energy efficiency and prevents diabetes in mice, Cell Metab., 8, 333, 10.1016/j.cmet.2008.08.014
Barger, 2008, Short-term consumption of a resveratrol-containing nutraceutical mixture mimics gene expression of long-term caloric restriction in mouse heart, Exp. Gerontol., 43, 859, 10.1016/j.exger.2008.06.013
Barger, 2008, A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice, PLoS ONE, 3, e2264, 10.1371/journal.pone.0002264
Baur, 2006, Therapeutic potential of resveratrol: the in vivo evidence, Nat. Rev. Drug Discov., 5, 493, 10.1038/nrd2060
Baur, 2006, Resveratrol improves health and survival of mice on a high-calorie diet, Nature, 444, 337, 10.1038/nature05354
Baur, 2010, Dietary restriction: standing up for sirtuins, Science, 329, 1012, 10.1126/science.329.5995.1012
Beher, 2009, Resveratrol is not a direct activator of SIRT1 enzyme activity, Chem. Biol. Drug Des., 74, 619, 10.1111/j.1747-0285.2009.00901.x
Bjorklund, 2011, Resveratrol induces SIRT1- and energy-stress-independent inhibition of tumor cell regrowth after low-dose platinum treatment, Cancer Chemother. Pharmacol., 68, 1459, 10.1007/s00280-011-1640-x
Boily, 2008, SirT1 regulates energy metabolism and response to caloric restriction in mice, PLoS One, 3, e1759, 10.1371/journal.pone.0001759
Boily, 2009, SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol, Oncogene, 28, 2882, 10.1038/onc.2009.147
Bordone, 2005, Calorie restriction, SIRT1 and metabolism: understanding longevity, Nat. Rev. Mol. Cell Biol., 6, 298, 10.1038/nrm1616
Bordone, 2007, SIRT1 transgenic mice show phenotypes resembling calorie restriction, Aging Cell, 6, 759, 10.1111/j.1474-9726.2007.00335.x
Borra, 2005, Mechanism of human SIRT1 activation by resveratrol, J. Biol. Chem., 280, 17187, 10.1074/jbc.M501250200
Brasnyo, 2011, Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients, Br. J. Nutr., 106, 383, 10.1017/S0007114511000316
Breen, 2008, Stimulation of muscle cell glucose uptake by resveratrol through sirtuins and AMPK, Biochem. Biophys. Res. Commun., 374, 117, 10.1016/j.bbrc.2008.06.104
Canto, 2009, AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity, Nature, 458, 1056, 10.1038/nature07813
Centeno-Baez, 2011, Resveratrol inhibition of inducible nitric oxide synthase in skeletal muscle involves AMPK but not SIRT1, Am. J. Physiol. Endocrinol. Metab., 301, E922, 10.1152/ajpendo.00530.2010
Chen, 2005, Increase in activity during calorie restriction requires Sirt1, Science, 310, 1641, 10.1126/science.1118357
Cheng, 2003, Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice, Proc. Natl. Acad. Sci. USA, 100, 10794, 10.1073/pnas.1934713100
Cohen, 2004, Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase, Science, 305, 390, 10.1126/science.1099196
Crandall, 2012, Pilot study of resveratrol in older adults with impaired glucose tolerance, J. Gerontol. A. Biol. Sci. Med. Sci., 10.1093/gerona/glr235
Csiszar, 2009, Resveratrol induces mitochondrial biogenesis in endothelial cells, Am. J. Physiol. Heart Circ. Physiol., 297, H13, 10.1152/ajpheart.00368.2009
Dai, 2010, SIRT1 activation by small molecules: kinetic and biophysical evidence for direct interaction of enzyme and activator, J. Biol. Chem., 285, 32695, 10.1074/jbc.M110.133892
Dasgupta, 2007, Resveratrol stimulates AMP kinase activity in neurons, Proc. Natl. Acad. Sci. USA, 104, 7217, 10.1073/pnas.0610068104
de Moura, 2010, Mitochondrial dysfunction in neurodegenerative diseases and cancer, Environ. Mol. Mutagen., 51, 391
Dong, 2011, SIRT1 is associated with a decrease in acute insulin secretion and a sex specific increase in risk for type 2 diabetes in Pima Indians, Mol. Genet. Metab., 104, 661, 10.1016/j.ymgme.2011.08.001
Donmez, 2010, Aging and disease: connections to sirtuins, Aging Cell, 9, 285, 10.1111/j.1474-9726.2010.00548.x
Donmez, 2010, SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10, Cell, 142, 320, 10.1016/j.cell.2010.06.020
Feige, 2008, Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation, Cell Metab., 8, 347, 10.1016/j.cmet.2008.08.017
Figueiredo, 2009, Aging impairs skeletal muscle mitochondrial bioenergetic function, J. Gerontol. A Biol. Sci. Med. Sci., 64, 21, 10.1093/gerona/gln048
Fillmore, 2010, Chronic AMP-activated protein kinase activation and a high-fat diet have an additive effect on mitochondria in rat skeletal muscle, J. Appl. Physiol., 109, 511, 10.1152/japplphysiol.00126.2010
Finsterer, 2004, Mitochondriopathies, Eur. J. Neurol., 11, 163, 10.1046/j.1351-5101.2003.00728.x
Firestein, 2008, The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth, PLoS ONE, 3, e2020, 10.1371/journal.pone.0002020
Fischer-Posovszky, 2010, Resveratrol regulates human adipocyte number and function in a Sirt1-dependent manner, Am. J. Clin. Nutr., 92, 5, 10.3945/ajcn.2009.28435
Frezza, 2007, Organelle isolation: functional mitochondria from mouse liver, muscle and cultured fibroblasts, Nat. Protoc., 2, 287, 10.1038/nprot.2006.478
Fulco, 2008, Comparing and contrasting the roles of AMPK and SIRT1 in metabolic tissues, Cell Cycle, 7, 3669, 10.4161/cc.7.23.7164
Fulco, 2008, Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt, Dev. Cell, 14, 661, 10.1016/j.devcel.2008.02.004
Gerhart-Hines, 2007, Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha, EMBO J., 26, 1913, 10.1038/sj.emboj.7601633
Gledhill, 2007, Mechanism of inhibition of bovine F1-ATPase by resveratrol and related polyphenols, Proc. Natl. Acad. Sci. USA, 104, 13632, 10.1073/pnas.0706290104
Gomes, 2012, Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis, Biochim. Biophys. Acta, 1822, 185, 10.1016/j.bbadis.2011.10.008
Gracia-Sancho, 2010, Activation of SIRT1 by resveratrol induces KLF2 expression conferring an endothelial vasoprotective phenotype, Cardiovasc. Res., 85, 514, 10.1093/cvr/cvp337
Haigis, 2010, Mammalian sirtuins: biological insights and disease relevance, Annu. Rev. Pathol., 5, 253, 10.1146/annurev.pathol.4.110807.092250
Hawley, 2010, Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation, Cell Metab., 11, 554, 10.1016/j.cmet.2010.04.001
He, 2010, Resveratrol prevents RANKL-induced osteoclast differentiation of murine osteoclast progenitor RAW 264.7 cells through inhibition of ROS production, Biochem. Biophys. Res. Commun., 401, 356, 10.1016/j.bbrc.2010.09.053
Herranz, 2010, Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer, Nat Commun, 1, 3, 10.1038/ncomms1001
Horvath, 2011, GPA protects the nigrostriatal dopamine system by enhancing mitochondrial function, Neurobiol. Dis., 43, 152, 10.1016/j.nbd.2011.03.005
Hou, 2008, SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase, J. Biol. Chem., 283, 20015, 10.1074/jbc.M802187200
Howitz, 2003, Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan, Nature, 425, 191, 10.1038/nature01960
Hwang, 2009, Pharmacological stimulation of NADH oxidation ameliorates obesity and related phenotypes in mice, Diabetes, 58, 965, 10.2337/db08-1183
Ivanov, 2008, Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression, Exp. Cell Res., 314, 1163, 10.1016/j.yexcr.2007.12.012
Jager, 2007, AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha, Proc. Natl. Acad. Sci. USA, 104, 12017, 10.1073/pnas.0705070104
Jang, 1997, Cancer chemopreventive activity of resveratrol, a natural product derived from grapes, Science, 275, 218, 10.1126/science.275.5297.218
Kaeberlein, 2005, Substrate-specific activation of sirtuins by resveratrol, J. Biol. Chem., 280, 17038, 10.1074/jbc.M500655200
Kao, 2010, Resveratrol protects human endothelium from H(2)O(2)-induced oxidative stress and senescence via SirT1 activation, J. Atheroscler. Thromb., 17, 970, 10.5551/jat.4333
Kim, 2007, SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis, EMBO J., 26, 3169, 10.1038/sj.emboj.7601758
Kim, 2011, SIRT1 activation by resveratrol ameliorates cisplatin-induced renal injury through deacetylation of p53, Am. J. Physiol. Renal Physiol., 301, F427, 10.1152/ajprenal.00258.2010
Knight, 2011, Mediobasal hypothalamic SIRT1 is essential for resveratrol's effects on insulin action in rats, Diabetes, 60, 2691, 10.2337/db10-0987
Lagouge, 2006, Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha, Cell, 127, 1109, 10.1016/j.cell.2006.11.013
Lan, 2008, SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation, J. Biol. Chem., 283, 27628, 10.1074/jbc.M805711200
Li, 2010, Resveratrol inhibits renal fibrosis in the obstructed kidney: potential role in deacetylation of Smad3, Am. J. Pathol., 177, 1065, 10.2353/ajpath.2010.090923
Lin, 2010, Resveratrol modulates tumor cell proliferation and protein translation via SIRT1-dependent AMPK activation, J. Agric. Food Chem., 58, 1584, 10.1021/jf9035782
Lowell, 2005, Mitochondrial dysfunction and type 2 diabetes, Science, 307, 384, 10.1126/science.1104343
Mader, 2010, Identification of a novel proapoptotic function of resveratrol in fat cells: SIRT1-independent sensitization to TRAIL-induced apoptosis, FASEB J., 24, 1997, 10.1096/fj.09-142943
McBurney, 2003, The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis, Mol. Cell. Biol., 23, 38, 10.1128/MCB.23.1.38-54.2003
Minor, 2011, SRT1720 improves survival and healthspan of obese mice, Sci. Rep., 1, 70, 10.1038/srep00070
Morino, 2006, Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction, Diabetes, 55, S9, 10.2337/db06-S002
Oberdoerffer, 2008, SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging, Cell, 135, 907, 10.1016/j.cell.2008.10.025
Ohguchi, 2010, SIRT1 modulates expression of matrix metalloproteinases in human dermal fibroblasts, Br. J. Dermatol., 163, 689, 10.1111/j.1365-2133.2010.09825.x
Pacholec, 2010, SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1, J. Biol. Chem., 285, 8340, 10.1074/jbc.M109.088682
Park, 2010, Role of resveratrol in FOXO1-mediated gluconeogenic gene expression in the liver, Biochem. Biophys. Res. Commun., 403, 329, 10.1016/j.bbrc.2010.11.028
Park, 2012, Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases, Cell, 148, 421, 10.1016/j.cell.2012.01.017
Pearson, 2008, Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span, Cell Metab., 8, 157, 10.1016/j.cmet.2008.06.011
Pfluger, 2008, Sirt1 protects against high-fat diet-induced metabolic damage, Proc. Natl. Acad. Sci. USA, 105, 9793, 10.1073/pnas.0802917105
Qin, 2006, Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction, J. Biol. Chem., 281, 21745, 10.1074/jbc.M602909200
Ramadori, 2009, Central administration of resveratrol improves diet-induced diabetes, Endocrinology, 150, 5326, 10.1210/en.2009-0528
Rasbach, 2010, PGC-1alpha regulates a HIF2alpha-dependent switch in skeletal muscle fiber types, Proc. Natl. Acad. Sci. USA, 107, 21866, 10.1073/pnas.1016089107
Rodgers, 2005, Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1, Nature, 434, 113, 10.1038/nature03354
Rolo, 2000, Bile acids affect liver mitochondrial bioenergetics: possible relevance for cholestasis therapy, Toxicol. Sci., 57, 177, 10.1093/toxsci/57.1.177
Rolo, 2003, Mitochondrially mediated synergistic cell killing by bile acids, Biochim. Biophys. Acta, 1637, 127, 10.1016/S0925-4439(02)00224-7
Rutanen, 2010, SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity, Diabetes, 59, 829, 10.2337/db09-1191
Ruzankina, 2007, Relationships between stem cell exhaustion, tumour suppression and ageing, Br. J. Cancer, 97, 1189, 10.1038/sj.bjc.6604029
Ruzankina, 2007, Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss, Cell Stem Cell, 1, 113, 10.1016/j.stem.2007.03.002
Sahin, 2011, Telomere dysfunction induces metabolic and mitochondrial compromise, Nature, 470, 359, 10.1038/nature09787
Scarpulla, 2011, Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network, Biochim. Biophys. Acta, 1813, 1269, 10.1016/j.bbamcr.2010.09.019
Sequeira, 2008, sirt1-null mice develop an autoimmune-like condition, Exp. Cell Res., 314, 3069, 10.1016/j.yexcr.2008.07.011
Shindler, 2010, Oral resveratrol reduces neuronal damage in a model of multiple sclerosis, J. Neuroophthalmol., 30, 328, 10.1097/WNO.0b013e3181f7f833
Smith, 2009, Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo, BMC Syst. Biol., 3, 31, 10.1186/1752-0509-3-31
Srere, 1963, The citrate condensing enzyme of pigeon breast muscle and moth flight muscle, Acta Chem. Scand., 17, S129, 10.3891/acta.chem.scand.17s-0129
Sulaiman, 2010, Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy, Am. J. Physiol. Heart Circ. Physiol., 298, H833, 10.1152/ajpheart.00418.2009
Tanno, 2010, Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure, J. Biol. Chem., 285, 8375, 10.1074/jbc.M109.090266
Um, 2010, AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol, Diabetes, 59, 554, 10.2337/db09-0482
Ungvari, 2009, Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells, Am. J. Physiol. Heart Circ. Physiol., 297, H1876, 10.1152/ajpheart.00375.2009
Valenzano, 2006, Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate, Curr. Biol., 16, 296, 10.1016/j.cub.2005.12.038
Vetterli, 2011, Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism, J. Biol. Chem., 286, 6049, 10.1074/jbc.M110.176842
Wallace, 2005, A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine, Annu. Rev. Genet., 39, 359, 10.1146/annurev.genet.39.110304.095751
Wallace, 2010, Mitochondrial DNA mutations in disease and aging, Environ. Mol. Mutagen., 51, 440
Wenz, 2009, Increased muscle PGC-1alpha expression protects from sarcopenia and metabolic disease during aging, Proc. Natl. Acad. Sci. USA, 106, 20405, 10.1073/pnas.0911570106
Xia, 2011, Resveratrol attenuates apoptosis of pulmonary microvascular endothelial cells induced by high shear stress and proinflammatory factors, Hum. Cell, 24, 127, 10.1007/s13577-011-0031-2
Yang, 2010, Effects of resveratrol on NO secretion stimulated by insulin and its dependence on SIRT1 in high glucose cultured endothelial cells, Endocrine, 37, 365, 10.1007/s12020-010-9314-8
Yoshizaki, 2010, SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity, Am. J. Physiol. Endocrinol. Metab., 298, E419, 10.1152/ajpendo.00417.2009
Zhang, 2006, Resveratrol inhibits insulin responses in a SirT1-independent pathway, Biochem. J., 397, 519, 10.1042/BJ20050977
Zini, 1999, Effects of resveratrol on the rat brain respiratory chain, Drugs Exp. Clin. Res., 25, 87
