SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function
Nathan L. Price1, Ana P. Gomes1,2, Alvin J.Y. Ling1, Filipe V. Duarte2, Alejandro Martin-Montalvo3, Brian J. North1, Beamon Agarwal4, Lan Ye4, Giorgio Ramadori5, Joao S. Teodoro2, Basil P. Hubbard1, Ana T. Varela2, James G. Davis4, Behzad Varamini4, Angela Hafner1, Ruin Moaddel6, Anabela P. Rolo2,7, Roberto Coppari5,8, Carlos M. Palmeira2,9, Rafael de Cabo3
1Glenn Labs for the Biological Mechanisms of Aging, Harvard Medical School, Boston, MA 02115, USA
2Center for Neurosciences and Cell Biology, 3004-517 Coimbra, Portugal
3Laboratory of Experimental Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA
4Perelman School of Medicine, University of Pennsylvania, Philadelphia PA 19104, USA
5Department of Internal Medicine, Division of Hypothalamic Research, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
6Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA
7Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal
8Dipartimento di Medicina Sperimentale e Clinica, Universita' Politecnica delle Marche, Ancona 60020, Italy
9Department of Life Sciences, Faculty of Science and Technology, University of Coimbra, 3004-517 Coimbra, Portugal
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Cell Metabolism
Tập 15
675-690
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