Discovery of new indomethacin-based analogs with potentially selective cyclooxygenase-2 inhibition and observed diminishing to PGE2 activities

European Journal of Medicinal Chemistry - Tập 141 - Trang 306-321 - 2017
Shaymaa E. Kassab1, Mohammed A. Khedr2, Hamed I. Ali2,3, Mohamed M. Abdalla4
1Pharmaceutical Chemistry Department, Faculty of Pharmacy, Damanhour University, Damanhour, El-Buhaira, 22516, Egypt
2Pharmaceutical Chemistry Department, Faculty of Pharmacy, Helwan University, Ein Helwan, Cairo 11795, Egypt
3Department of Pharmaceutical Sciences, Texas A&M University Irma Lerma Rangel College of Pharmacy, Kingsville 78363, Texas, USA
4Research Unit, Saco Pharm. Co., 6th of October City, Giza 68330, Egypt

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