Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial
Sheena McCormack1,2, David T Dunn1, Monica Desai1,3, David I Dolling1, Mitzy Gafos1, Richard Gilson4,5, Ann K Sullivan6, Amanda Clarke7, Iain Reeves8, Gabriel Schembri9, Nicola Mackie10, Christine Bowman11, Charles J Lacey12, Vanessa Apea13, Michael Brady14, Julie Fox15, Stephen Taylor16, Simone Antonucci2, Saye H Khoo17, James Rooney18
1MRC Clinical Trials Unit at UCL, London, UK
256 Dean Street, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK
3HIV & STI Department, Public Health England Centre for Infectious Disease Surveillance and Control, London, UK
4The Mortimer Market Centre, Central and North West London NHS Foundation Trust, London, UK
5Research Department of Infection and Population Health, University College London, London, UK
6St Stephen's Centre, Chelsea and Westminster Healthcare NHS Foundation Trust, London, UK
7Claude Nicol Centre, Royal Sussex County Hospital, Brighton & Sussex University Hospitals NHS Trust, Brighton, UK
8Homerton University Hospital NHS Foundation Trust, London, UK
9Manchester Centre for Sexual Health, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK
10St Mary's Hospital, Imperial College Healthcare NHS Foundation Trust, London, UK
11Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
12York Teaching Hospital and Hull York Medical School, University of York, York, UK
13Ambrose King Centre and Barts Sexual Health Centre, Barts Health NHS Trust, London, UK
14King’s College Hospital NHS Foundation Trust, London, UK
15Guy’s and St Thomas’ NHS Foundation Trust, London, UK
16Birmingham Heartlands Hospital, Heart of England NHS Foundation Trust, Birmingham, UK
17University of Liverpool, Liverpool, UK
18Gilead Sciences, Foster City, CA, USA